Create issue ticket

31 Possible Causes for Central Nervous System Disorder, Hyperintensities in the Globus Pallidus (T2-Weighted), Mental Retardation

Did you mean: Central Nervous System Disorder, Hyperintensities in the Globus Pallidus (T2-Weighted, Mental Retardation

  • Hallervorden-Spatz Syndrome

    Clinical presentations include dystonia, dysarthria, dementia, severe mental retardation and ataxia with rare features as rigidity, choreoathetosis, seizures, optic atrophy[medresearch.in] , Nervous System Diseases Nervous System Diseases Neurodegenerative Diseases Heredodegenerative Disorders, Nervous System Central Nervous System Diseases Movement Disorders[hon.ch] This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov]

  • Alexander Disease

    The patient initially presented at 9 months of age, with profound mental retardation and a history of seizures.[ncbi.nlm.nih.gov] […] the central nervous system.[naset.org] In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[ncbi.nlm.nih.gov]

  • Fucosidosis

    The early symptom of anterior beaking of the vertebral bodies, in combination with mental retardation and angiokeratoma corporis diffusum, can suggest the possibility of type[ncbi.nlm.nih.gov] The disorder affects dogs between 18 months and 4 years of age. Clinically, the disease is characterised by a decrease in central nervous system functions.[vetgen.com] Figure 2: Magnetic resonance imaging brain T2-weighted axial image showing hypointensity of globus pallidus bilaterally and the subcortical hyperintensity (a), T1-weighted[pediatricneurosciences.com]

  • Binswanger Disease

    What are Neurological Disorders? Neurological disorders are diseases of the central and peripheral nervous system.[plusonefoundation.org] The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] 386 Hydrocephalus and retarded myelination 388 Mental retardation physically handicapped 390 Pelizaeus Merzbacher 392 Pelizaeus Merzbacher 394 Metachromatic leukodystrophy[books.google.de]

  • Neurodegeneration with Brain Iron Accumulation

    nervous system (CNS).[ncbi.nlm.nih.gov] Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] retardation, retinitis pigmentosa and iron accumulation in the brain.[ncbi.nlm.nih.gov]

  • Neurofibromatosis Type 1

    All patients with uncontrolled seizures had severe mental retardation, and three of these had malformations of cortical development.[ncbi.nlm.nih.gov] While NF1 primarily affects the central and peripheral nervous system, multisystem involvement is the rule, with dermatologic, cardiovascular, gastrointestinal, and orthopedic[ncbi.nlm.nih.gov] Rarely, hyperintensities and mild mass effect have been reported in the globus pallidus on T1-weighted images.[emedicine.com]

  • Mercury Poisoning

    Mercury's harmful effects that may be passed from the mother to the fetus include brain damage, mental retardation, incoordination, blindness, seizures, and inability to speak[web.archive.org] Delayed toxicity symptoms ( 1 month) are typical of organic mercury poisoning and usually involve the central nervous system.[floridahealth.gov] The T2-weighted MRI images of the patient's brain initially showed multiple hyperintense lesions in cerebral white matter, left globus pallidus, and putamen, which also improved[ncbi.nlm.nih.gov]

  • 2-Hydroxyglutaric Aciduria

    Central nervous system tumors are encountered in children with other metabolic neurodegenerative disorders.[ncbi.nlm.nih.gov] In 43 patients (77%) the globus pallidus was more hyperintense on the T2-weighted MR images than the caudate nucleus and putamen ( , Fig 5 ).[pubs.rsna.org] Patients present a very slowly progressive deterioration with cerebellar ataxia, mild or severe mental retardation, and various other clinical signs including extrapyramidal[ncbi.nlm.nih.gov]

  • Kernicterus

    These central nervous system (CNS) sequelae reflect the regional topography of bilirubin-induced neuropathology, which involves the globus pallidus, subthalamic nucleus, brain-stem[blogs.nejm.org] In the appropriate clinical context, bilateral globus pallidus T2-weighted and FLAIR signal hyperintensity is supportive of a diagnosis of kernicterus in an infant.[imj.ie] retardation.[medicinenet.com]

  • Woodhouse Sakati Syndrome

    The rare, genetically determined group of diseases characterized by pathological accumulation of iron in the central nervous system and progressive, typically movement disorder's[pubtransformer.com] Axial FLAIR- (A) and GRE T2-weighted (B) MRI discloses ‘ eye-of- the-tiger ’ sign, defined as a medial area of hyperintense signal within an hypointense signal in globus pallidus[scielo.br] A syndrome of hypogonadism, alopecia, diabetes mellitus, mental retardation, deafness, and ECG abnormalities.[doi.org]

Similar symptoms