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15 Possible Causes for Central Nervous System Disorder, Hyperintensities in the Globus Pallidus (T2-Weighted), Peripheral Sensory Neuropathy

Did you mean: Central Nervous System Disorder, Hyperintensities in the Globus Pallidus (T2-Weighted, Peripheral Sensory Neuropathy

  • Mercury Poisoning

    Delayed toxicity symptoms ( 1 month) are typical of organic mercury poisoning and usually involve the central nervous system.[floridahealth.gov] The T2-weighted MRI images of the patient's brain initially showed multiple hyperintense lesions in cerebral white matter, left globus pallidus, and putamen, which also improved[ncbi.nlm.nih.gov] Very dangerous, it meant that the hatters were subject to erethism, a neurological disorder which affects the whole central nervous system.[dailymail.co.uk]

  • Wernicke Encephalopathy

    In many patients with no symptoms of peripheral neuropathy, examination may reveal diminished or absent ankle jerks and patchy distal sensory loss.[clinicaladvisor.com] […] lesions of the central nervous system after exhaustion of B-vitamin reserves, Wernicke's disease Wernicke's disease (disorder) Wernicke's encephalopathy Statements Identifiers[wikidata.org] […] in the globus pallidus.[ncbi.nlm.nih.gov]

  • Neuromyelitis Optica

    Other peripheral neuropathies Antimyelin-associated glycoprotein (MAG) neuropathy is an antibody-mediated demyelinating neuropathy clinically characterised by distal, symmetric[doi.org] Overview Neuromyelitis optica (NMO) is a central nervous system disorder that primarily affects the eye nerves (optic neuritis) and the spinal cord (myelitis).[mayoclinic.org] To aid in diagnosis, other MR imaging features include the following: cerebral atrophy; hyperintensities on T2-weighted images in the dentate nuclei, globus pallidus, substantia[pubs.rsna.org]

  • McLeod Neuroacanthocytosis Syndrome

    The latter disorders are characterized by a peripheral neuropathy and sensory ataxia due to dorsal column degeneration, but movement disorders and cognitive impairment are[scienceopen.com] McLeod neuroacanthocytosis syndrome (MLS) is a multisystem disorder with central nervous system (CNS), neuromuscular, and hematologic manifestations in males.[rareconnect.org] neuropathy and sensory ataxia due to dorsal column degeneration, but without movement disorders.[ojrd.biomedcentral.com]

  • Alpers Syndrome

    Ataxia neuropathy spectrum (ANS) Characterized by sensory or cerebellar ataxia and peripheral sensory neuropathy, although approximately two-thirds also develop epilepsy,[radiopaedia.org] […] and that (ii) central nervous system and further organ affection may only develop in the time course of the disease.[ncbi.nlm.nih.gov] The right parietal cortex appears normal in the T2-weighted images.[ajnr.org]

  • Axonal Neuropathy

    […] system. 1,2 The disease stems from gigaxonin gene mutations resulting in disorganization of axonal intermediate filaments. 2 Pronounced peripheral motor and sensory neuropathy[appliedradiology.com] This disorder is characterized by abnormalities in the peripheral and central nervous systems including low muscle tone (hypotonia), muscle weakness, decreased reflexes, impaired[rarediseases.org] AIDS peripheral neuropathy Direct infection of peripheral nerves by HIV, resulting in sensory and motor changes due to destruction of axons or their myelin covering.[medical-dictionary.thefreedictionary.com]

  • Autosomal Dominant Progressive External Ophthalmoplegia Type 6

    neuropathy resulting in reduced/absent deep tendon reflexes and sensory impairment.[mendelian.co] Central nervous system imaging in mitochondrial disorders. Can J Neurol Sci 2009;36:143-153. PubMed Abstract. 8. Finsterer J. Mitochondrial neuropathy.[bcmj.org] T2-weighted axial MR image demonstrates bilateral hyperintense signal abnormalities in the globus pallidus (arrows).[collections.lib.utah.edu]

  • Creutzfeldt Jakob Disease

    CJD E200K–129M patients also show signs of motor and sensory peripheral neuropathy rarely found in sCJD patients.[doi.org] The presence of 14-3-3 proteins in CSF strongly suggests CJD, but this protein may be seen in other central nervous system disorders and is not pathognomonic of CJD [ 25 ][doi.org] Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org]

  • Disorder of Manganese Transport

    Peripheral neuropathy Peripheral neuropathy, as demonstrated by hyporeflexia and peripheral sensory changes is characteristic of the two core neuroacanthocytosis syndromes[movementdisorders.org] Implications of manganese in diseases, especially central nervous system disorders. In: Yasui M, Strong MJ, Ota K, et al, eds. Mineral and Metal Neurotoxicology.[ajnr.org] Furthermore, abnormally high/low trace metal content in the central nervous system has been associated with a variety of neurological disorders, for example Parkinson's disease[docs.lib.purdue.edu]

  • Infantile Symmetrical Thalamic Degeneration

    Clinically, vitamin E deficiency causes a sensory peripheral neuropathy, ataxia, retinitis pigmentosa, and skeletal and cardiac myopathy.[neuropathology-web.org] INTRODUCTION Degenerative disorders of the central nervous system encompass a wide range of genetic and metabolic conditions, which result in progressive neurologic disability[neupsykey.com] T2-weighted MR images show characteristically symmetrical hyperintense lesions in the cerebral white matter, globus pallidus, thalamus, midbrain, and pons, as well as bilateral[ajnr.org]

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