Central Nervous System Involvement: Causes & Reasons

Possible Causes for Central Nervous System Involvement

To report two cases of hypereosinophilic syndrome (HES) with central nervous system involvement and explore its possible pathogenesis. [ncbi.nlm.nih.gov]

The central nervous system (CNS) may be affected in those cases of peripheral eosinophila without a secondary cause (hypereosinophilic syndrome, HES). [ncbi.nlm.nih.gov]

1 had cardiac and central nervous system involvement; and 1 had skin involvement. [ncbi.nlm.nih.gov]

Secondary Hypereosinophilic Syndrome

Other common complications include central or peripheral nervous system involvement, hepato- and/or splenomegaly, and coagulation disorders. [orpha.net]

In this paper, we describe a case of idiopathic HES with cardiac, pulmonary, and central nervous system involvement. [karger.com]

Clinical manifestations of HES depend on the organ system involved, and the skin, heart, lungs, and central or peripheral nervous system are involved in >50% of patients. [jrd.or.kr]

Acute Hepatic Porphyria

All components of the peripheral nervous system and the central nervous system may be involved. Motor neuropathy is common with severe and prolonged attacks. [msdmanuals.com]

The probable mechanism includes the syndrome of inappropriate antidiuretic hormone secretion (SIADH) due to central nervous system (CNS) involvement, gastrointestinal or renal [ncbi.nlm.nih.gov]

Central nervous system involvement may cause seizures or mental disturbances (eg, apathy, depression, agitation, frank psychosis, hallucinations). [msdmanuals.com]

Malignant Angioendotheliomatosis

Although the disease primarily involves the vasculature of the skin and central nervous system, vascular involvement of other organs may occur and may produce a variety of [ncbi.nlm.nih.gov]

Multiple organ systems are involved and the clinical presentation resembles a systemic necrotizing vasculitis with skin and central nervous system most commonly involved. [ncbi.nlm.nih.gov]

Blue Rubber Bleb Nevus Syndrome

We report a rare case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement. [ncbi.nlm.nih.gov]

However, well-documented central nervous system angiomata are rarely encountered. We present herein the case of a young adult with central nervous system involvement. [jamanetwork.com]

The central nervous system involvement is seldom reported, and neurological symptoms at onset in adulthood are extremely rare. [ncbi.nlm.nih.gov]

Lupus Encephalitis

Central nervous system (CNS) involvement has been emphasised as one of the major lupus manifestations since the first descriptions of the disease and is among the leading [lupusuk.org.uk]

Karassa FB, Ioannidis JP, Touloumi G, Boki KA, Moutsopoulos HM (2000) Risk factors for central nervous system involvement in systemic lupus erythematosus. [journals.plos.org]

In six children, headache was the initial symptom of central nervous system involvement. [journals.sagepub.com]

Systemic Lupus Erythematosus with Organ/System Involvement

Abstract Central nervous system involvement is a common but rarely reviewed feature of pediatric systemic lupus erythematosus (SLE). [ncbi.nlm.nih.gov]

Only one patient had associated central nervous system involvement at that time. All patients were positive for IgM and IgG anticardiolipin antibodies. [ncbi.nlm.nih.gov]

OBJECTIVE: To describe the psychiatric presentation, serologic findings, and neuroimaging patterns in children and adolescents with central nervous system involvement with [ncbi.nlm.nih.gov]

Bickerstaff Brainstem Encephalitis

system involvement with cortical, subcortical and cerebellar lesions on brain magnetic resonance imaging (MRI), and was eventually diagnosed with BBE. [psasir.upm.edu.my]

nervous system involvement in the Miller Fisher syndrome. [collections.lib.utah.edu]

It is considered to be a variant of Miller Fisher syndrome and Guillain-Barré syndrome but is differentiated from the two by the presence of central nervous system involvement [ncbi.nlm.nih.gov]

Lymphomatoid Granulomatosis

An extensive systemic work-up ruled out other site(s) of involvement. [ncbi.nlm.nih.gov]

Because central nervous system (CNS) involvement of LYG has been known to show poor prognosis, the establishment of an effective treatment for CNS LYG with mild adverse effects [ncbi.nlm.nih.gov]

It predominantly affects the lungs, skin, liver, kidneys, spleen, and central nervous system. Testicular involvement has never previously been described. [ncbi.nlm.nih.gov]

Pulmonary Lymphomatoid Granulomatosis

In some young patient with LYG were detected central nervous system involvement or skin involvement without pulmonary involvement. [siicsalud.com]

Many patients die as a result of pulmonary hemorrhage, central nervous system involvement, or transformation to an aggressive lymphoma. [synapse.koreamed.org]

Isolated central nervous system involvement by lymphomatoid granulomatosis in an adolescent: A case report and review of literature. [ncbi.nlm.nih.gov]

Orbital Burkitt's Lymphoma

Fourteen (88%) of the patients had systemic involvement, of which the most common locations were central nervous system (6/16), lymphatics (6/16), bone marrow (6/16), and [ncbi.nlm.nih.gov]

nervous system involvement Acute paraplegia, urinary and fecal incontinence are symptoms due to spinal cord compression. [explainmedicine.com]

nervous system lymphoma in a patient with orbital non-Hodgkin’s lymphoma is 5.9%,(12) and the most common form of central nervous system involvement in lymphoma is leptomeningeal [djo.harvard.edu]

CINCA Syndrome

Some patients present with the full early-onset pathognomonic clinical picture, with central nervous system involvement and early onset arthropathies. [orpha.net]

nervous system involvement. [ncbi.nlm.nih.gov]

Result It exhibits a typical triad: generalized urticaria and maculopapular rash was present at birth, central nervous system involvement with chronic meningitis and joint [jacionline.org]

Late-Onset Pompe Disease

Central nervous system and cerebrovascular involvement The central and peripheral nervous systems are also involved in LOPD. [ncbi.nlm.nih.gov]

Central nervous system involvement in late-onset Pompe disease: clues from neuroimaging and neuropsychological analysis. Eur J Neurol. 2019;26(3):442–e35. [ojrd.biomedcentral.com]

Central nervous system involvement in late-onset Pompe disease: clues from neuroimaging and neuropsychological analysis. [ncbi.nlm.nih.gov]

Neurologic Manifestation of Whipple Disease

Central Nervous System involvement is not uncommon and it may precede other disease manifestations, appear after treatment and improvement of gastrointestinal signs or rarely [benthamopen.com]

Lumbar puncture was done to look for central nervous system involvement, and PCR for Tropheryma whipplei in the CSF was positive. [shmabstracts.com]

More than 70 leading experts provide comprehensive, current information on all infections—both neural-specific and systemic—that involve the central nervous system. [books.google.com]

Malignant Atrophic Papulosis

nervous system involvement in a child. [scholars.northwestern.edu]

She died as a result of central nervous system involvement from Degos' disease. [ncbi.nlm.nih.gov]

Malignant atrophic papulosis (Kohlmeier-Degos disease) is reported for the first time with pathologic verification of central nervous system involvement in a child. [ncbi.nlm.nih.gov]

Congenital Merosin-Positive Muscular Dystrophy

nervous system involvement. [pubfacts.com]

[…] we describe a 3-year-old Mediterranean child with clinical and histopathological signs of CMD, normal expression of merosin, severe clinical and radiological evidence of central [ncbi.nlm.nih.gov]

In general, central nervous system involvement is not present. There is also evidence for still unclassified forms. [ncbi.nlm.nih.gov]

Xanthoma Disseminatum

Ocular, liver, bone marrow, respiratory, skeletal, and central nervous system involvement may accompany the classic findings of the disease. [ncbi.nlm.nih.gov]

Central nervous system involvement is rare and usually occurs in the systemic variety. [ncbi.nlm.nih.gov]

We describe an illustrative case with extensive mucocutaneous, ocular, laryngeal, pituitary and central nervous system involvement, which responded to treatment with cyclophosphamide [ncbi.nlm.nih.gov]

Malignant Meningeal Lymphoma

PURPOSE: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. [ncbi.nlm.nih.gov]

Korsager S, Laursen B, Mortensen TM: Dementia and central nervous system involvement in chronic lymphocytic leukemia. [link.springer.com]

Tuberculosis of Nervous System

Do Not Do Recommendation For people with HIV (human immunodeficiency virus) and active TB (tuberculosis)without central nervous system involvement, do not routinely extend [nice.org.uk]

Abstract The incidence of tuberculosis in the United States is increasing in all age groups; 5% of all of these patients have central nervous system involvement. [ncbi.nlm.nih.gov]

Central nervous system involvement is one of the most serious forms of this infection, acting as a prominent cause of morbidity and mortality in developing countries. [journals.lww.com]

Rosai-Dorfman Disease

Central nervous system (CNS) involvement is infrequent and typically manifests as an isolated lesion. [ncbi.nlm.nih.gov]

Rosai-Dorfman disease with multiple lesions primarily involving the central nervous system is rare. [ncbi.nlm.nih.gov]

Central nervous system involvement is extremely rare, particularly cases with multiple intracranial masses. [ncbi.nlm.nih.gov]

Hemophagocytic Lymphohistiocytosis

The presence of central nervous system involvement has a profound impact on the prognosis, treatment, and clinical outcome of the disease. [ncbi.nlm.nih.gov]

Central nervous system involvement of HLH can cause catastrophic results. [ncbi.nlm.nih.gov]

Conclusions: Physicians managing patients with HLH must be vigilant about the possibility of central nervous system involvement including stroke. [ingentaconnect.com]

Mitochondrial Complex 3 Deficiency Nuclear Type 1

OBJECTIVE To report a rare manifestation of CoQ(10) deficiency with isolated mitochondrial myopathy without central nervous system involvement. [unboundmedicine.com]

Cancer and the Central Nervous System Involvement E-2292 134 Posttreatment Neurologic Sequelae of Pediatric Central Nervous System Tumors E-2297 135 Muscle and Nerve Development [books.google.com]

OBJECTIVE: To report a rare manifestation of CoQ(10) deficiency with isolated mitochondrial myopathy without central nervous system involvement. [unboundmedicine.com]

Whipple Disease

Central nervous system involvement, including severe cognitive deterioration, may precede systemic manifestations, appear during the course of the disease, or even be the [ncbi.nlm.nih.gov]

The central nervous system (CNS) is involved in 3 situations: CNS involvement in classic WD, CNS relapse in previously treated WD, and isolated CNS infection. [ncbi.nlm.nih.gov]

A subset of patients with the disease may either initially have or eventually develop symptoms of central nervous system involvement. [ncbi.nlm.nih.gov]

Behçet Disease

A rare combination of both cerebral venous thrombosis and parenchymal central nervous system involvement was identified by neuroimaging. [ncbi.nlm.nih.gov]

Recurrent mucocutaneous lesions may be the only symptoms in mild cases, but articular, ocular, vascular, and/or gastrointestinal and central nervous system involvement may [ncbi.nlm.nih.gov]

Brain Central nervous system involvement is one of the most dangerous manifestations of Behcet’s. [hopkinsvasculitis.org]

Juvenile Xanthogranuloma

Central nervous system involvement is a poor prognostic factor. [ncbi.nlm.nih.gov]

Solitary lesions in the spinal column are an especially rare presentation of this disease, and central nervous system involvement can portend a poor prognosis. [ncbi.nlm.nih.gov]

Which is the most common extracutaneous site of involvement? Eyes Central nervous system Lungs Bone Liver Board review style answer #1 A. [pathologyoutlines.com]

Cerebral Angiitis

licensee BioMed Central Ltd. 2012 Received: 7 February 2012 Accepted: 15 May 2012 Published: 13 September 2012 Abstract Introduction Central nervous system involvement [jmedicalcasereports.biomedcentral.com]

References 1 An unusual central nervous system involvement in rheumatoid arthritis: combination of pachymeningitis and cerebral vasculitis, Rheumatol Int, 2009, vol. 29 (pg [academic.oup.com]

A case of primary Sjögren’s syndrome presenting primarily with central nervous system vasculitic involvement. Rheumatol Int 2012;32(3): 805–807. [pubs.rsna.org]

Bloch Sulzberger Syndrome

How well a person does depends on the severity of central nervous system involvement and eye problems. [nlm.nih.gov]

nervous system involvement and eye problems. [ufhealth.org]

[…] www.ipif.org National Organization for Rare Disorders -- rarediseases.org/rare-diseases/incontinentia-pigmenti Outlook (Prognosis) How well a person does depends on the severity of central [ufhealth.org]

Miller-Fisher Syndrome

However some features of the disease are still debated, particularly regarding possible central nervous system involvement. [moh-it.pure.elsevier.com]

However there are occasional reports of central nervous system involvement. [ncbi.nlm.nih.gov]

nervous system involvement in the Miller Fisher syndrome. [collections.lib.utah.edu]

Neurosyphilis

[…] in central nervous system (CNS) disorders. [ncbi.nlm.nih.gov]

There is evidence for neurosyphilis being associated with the central nervous system vasculitis involving medium and small vessels. [ncbi.nlm.nih.gov]

Central nervous system involvement by this infection is referred to as neurosyphilis. [docneuro.com]

Hemangiomatosis

Described here is a case of diffuse neonatal hemangiomatosis with predominant central nervous system involvement. [ncbi.nlm.nih.gov]

[…] of the central nervous system. [jamanetwork.com]

One infant developed thrombocytopenia and bleeding while the other infant with more widely diffuse lesions succumbed to extensive central nervous system involvement. [pediatrics.aappublications.org]