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3,938 Possible Causes for Central Nervous System Involvement

  • Blue Rubber Bleb Nevus Syndrome

    We report a rare case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement.[ncbi.nlm.nih.gov] The central nervous system involvement is seldom reported, and neurological symptoms at onset in adulthood are extremely rare.[ncbi.nlm.nih.gov] Central nervous system involvement in BRBNS is not often reported, and most cases of BRBNS are sporadic.[ncbi.nlm.nih.gov]

  • Lupus Encephalitis

    Central nervous system (CNS) involvement has been emphasised as one of the major lupus manifestations since the first descriptions of the disease and is among the leading[lupusuk.org.uk] With severe central nervous system involvement, CSF levels of nitric oxide are found to be elevated and can help to monitor LC progression.[symptoma.com] Karassa FB, Ioannidis JP, Touloumi G, Boki KA, Moutsopoulos HM (2000) Risk factors for central nervous system involvement in systemic lupus erythematosus.[journals.plos.org]

  • Malignant Angioendotheliomatosis

    Although the disease primarily involves the vasculature of the skin and central nervous system, vascular involvement of other organs may occur and may produce a variety of[ncbi.nlm.nih.gov] Multiple organ systems are involved and the clinical presentation resembles a systemic necrotizing vasculitis with skin and central nervous system most commonly involved.[ncbi.nlm.nih.gov] All patients presented with symptoms referable to central nervous system (CNS) involvement. In two patients, the diagnosis was made on brain biopsy specimens.[ncbi.nlm.nih.gov]

  • CINCA Syndrome

    Some patients present with the full early-onset pathognomonic clinical picture, with central nervous system involvement and early onset arthropathies.[orpha.net] nervous system involvement.[ncbi.nlm.nih.gov] Central nervous system involvement is revealed by chronic headaches due to chronic meningitis with granulocytes. In the severe forms, intellectual deficit can occur.[orpha.net]

  • Congenital Merosin-Positive Muscular Dystrophy

    nervous system involvement.[pubfacts.com] […] we describe a 3-year-old Mediterranean child with clinical and histopathological signs of CMD, normal expression of merosin, severe clinical and radiological evidence of central[ncbi.nlm.nih.gov] In general, central nervous system involvement is not present. There is also evidence for still unclassified forms.[ncbi.nlm.nih.gov]

  • Erdheim-Chester Disease

    In ECD, central nervous system (CNS) and orbital lesions are frequent, and more than half of ECD pa tients carry the V600E mutation of the protooncogene BRAF.[ncbi.nlm.nih.gov] The exceptionally long history is particularly notable, given that ECD is a life-threatening disorder and there is a recognised association between central nervous system[ncbi.nlm.nih.gov] Central nervous system involvement, particularly of the spine, is rare.[ncbi.nlm.nih.gov]

  • Lymphomatoid Granulomatosis

    An extensive systemic work-up ruled out other site(s) of involvement.[ncbi.nlm.nih.gov] Because central nervous system (CNS) involvement of LYG has been known to show poor prognosis, the establishment of an effective treatment for CNS LYG with mild adverse effects[ncbi.nlm.nih.gov] The clinical features reflect systemic multi-organ disease with lung, skin, and central nervous system involvement.[secure.ssa.gov]

  • Malignant Atrophic Papulosis

    She died as a result of central nervous system involvement from Degos' disease.[ncbi.nlm.nih.gov] nervous system involvement in a child.[scholars.northwestern.edu] Malignant atrophic papulosis (Kohlmeier-Degos disease) is reported for the first time with pathologic verification of central nervous system involvement in a child.[ncbi.nlm.nih.gov]

  • Familial Hemophagocytic Lymphohistiocytosis

    The presence of central nervous system involvement has a profound impact on the prognosis, treatment, and clinical outcome of the disease.[ncbi.nlm.nih.gov] Central nervous system involvement of HLH can cause catastrophic results.[ncbi.nlm.nih.gov] Conclusions: Physicians managing patients with HLH must be vigilant about the possibility of central nervous system involvement including stroke.[ingentaconnect.com]

  • Whipple Disease

    Central nervous system involvement, including severe cognitive deterioration, may precede systemic manifestations, appear during the course of the disease, or even be the[ncbi.nlm.nih.gov] The central nervous system (CNS) is involved in 3 situations: CNS involvement in classic WD, CNS relapse in previously treated WD, and isolated CNS infection.[ncbi.nlm.nih.gov] A subset of patients with the disease may either initially have or eventually develop symptoms of central nervous system involvement.[ncbi.nlm.nih.gov]

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