Central Nervous System Involvement: Causes & Reasons

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Possible Causes for Central Nervous System Involvement

Acute Hepatic Porphyria

All components of the peripheral nervous system and the central nervous system may be involved. Motor neuropathy is common with severe and prolonged attacks. [msdmanuals.com]

The probable mechanism includes the syndrome of inappropriate antidiuretic hormone secretion (SIADH) due to central nervous system (CNS) involvement, gastrointestinal or renal [ncbi.nlm.nih.gov]

Central nervous system involvement may cause seizures or mental disturbances (eg, apathy, depression, agitation, frank psychosis, hallucinations). [msdmanuals.com]

Malignant Angioendotheliomatosis

Although the disease primarily involves the vasculature of the skin and central nervous system, vascular involvement of other organs may occur and may produce a variety of [ncbi.nlm.nih.gov]

Multiple organ systems are involved and the clinical presentation resembles a systemic necrotizing vasculitis with skin and central nervous system most commonly involved. [ncbi.nlm.nih.gov]

Blue Rubber Bleb Nevus Syndrome

We report a rare case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement. [ncbi.nlm.nih.gov]

Central nervous system involvement in BRBNS is not often reported, and most cases of BRBNS are sporadic. [ncbi.nlm.nih.gov]

Blue rubber bleb nevus syndrome with central nervous system involvement. Pediatr Neurol 2000;22:410–412. 2. Satya-Murti S, Navada S, Eames F. [n.neurology.org]

Bickerstaff Brainstem Encephalitis

system involvement with cortical, subcortical and cerebellar lesions on brain magnetic resonance imaging (MRI), and was eventually diagnosed with BBE. [psasir.upm.edu.my]

nervous system involvement in the Miller Fisher syndrome. [collections.lib.utah.edu]

[…] and peripheral nervous system involvement. [ncbi.nlm.nih.gov]

Systemic Lupus Erythematosus with Organ/System Involvement

Abstract Central nervous system involvement is a common but rarely reviewed feature of pediatric systemic lupus erythematosus (SLE). [ncbi.nlm.nih.gov]

Only one patient had associated central nervous system involvement at that time. All patients were positive for IgM and IgG anticardiolipin antibodies. [ncbi.nlm.nih.gov]

OBJECTIVE: To describe the psychiatric presentation, serologic findings, and neuroimaging patterns in children and adolescents with central nervous system involvement with [ncbi.nlm.nih.gov]

Lupus Encephalitis

In six children, headache was the initial symptom of central nervous system involvement. [journals.sagepub.com]

With severe central nervous system involvement, CSF levels of nitric oxide are found to be elevated and can help to monitor LC progression. [symptoma.com]

Sixteen children had seizures, and 12 children had seizures as the initial central nervous system involvement. [journals.sagepub.com]

Pulmonary Lymphomatoid Granulomatosis

In some young patient with LYG were detected central nervous system involvement or skin involvement without pulmonary involvement. [siicsalud.com]

Many patients die as a result of pulmonary hemorrhage, central nervous system involvement, or transformation to an aggressive lymphoma. [synapse.koreamed.org]

Isolated central nervous system involvement by lymphomatoid granulomatosis in an adolescent: A case report and review of literature. [surgicalneurologyint.com]

Lymphomatoid Granulomatosis

The clinical features reflect systemic multi-organ disease with lung, skin, and central nervous system involvement. [secure.ssa.gov]

It predominantly affects the lungs, skin, liver, kidneys, spleen, and central nervous system. Testicular involvement has never previously been described. [ncbi.nlm.nih.gov]

Because central nervous system (CNS) involvement of LYG has been known to show poor prognosis, the establishment of an effective treatment for CNS LYG with mild adverse effects [ncbi.nlm.nih.gov]

Orbital Burkitt's Lymphoma

Fourteen (88%) of the patients had systemic involvement, of which the most common locations were central nervous system (6/16), lymphatics (6/16), bone marrow (6/16), and [ncbi.nlm.nih.gov]

nervous system involvement Acute paraplegia, urinary and fecal incontinence are symptoms due to spinal cord compression. [explainmedicine.com]

nervous system lymphoma in a patient with orbital non-Hodgkin’s lymphoma is 5.9%,(12) and the most common form of central nervous system involvement in lymphoma is leptomeningeal [djo.harvard.edu]

CINCA Syndrome

Some patients present with the full early-onset pathognomonic clinical picture, with central nervous system involvement and early onset arthropathies. [orpha.net]

nervous system involvement. [ncbi.nlm.nih.gov]

Central nervous system involvement is revealed by chronic headaches due to chronic meningitis with granulocytes. In the severe forms, intellectual deficit can occur. [orpha.net]

Neurologic Manifestation of Whipple Disease

Lumbar puncture was done to look for central nervous system involvement, and PCR for Tropheryma whipplei in the CSF was positive. [shmabstracts.com]

Central Nervous System involvement is not uncommon and it may precede other disease manifestations, appear after treatment and improvement of gastrointestinal signs or rarely [benthamopen.com]

More than 70 leading experts provide comprehensive, current information on all infections—both neural-specific and systemic—that involve the central nervous system. [books.google.com]

Xanthoma Disseminatum

Ocular, liver, bone marrow, respiratory, skeletal, and central nervous system involvement may accompany the classic findings of the disease. [ncbi.nlm.nih.gov]

Central nervous system involvement is rare and usually occurs in the systemic variety. [ncbi.nlm.nih.gov]

We describe an illustrative case with extensive mucocutaneous, ocular, laryngeal, pituitary and central nervous system involvement, which responded to treatment with cyclophosphamide [ncbi.nlm.nih.gov]

Malignant Atrophic Papulosis

nervous system involvement in a child. [scholars.northwestern.edu]

She died as a result of central nervous system involvement from Degos' disease. [ncbi.nlm.nih.gov]

Malignant atrophic papulosis (Kohlmeier-Degos disease) is reported for the first time with pathologic verification of central nervous system involvement in a child. [ncbi.nlm.nih.gov]

Congenital Merosin-Positive Muscular Dystrophy

In general, central nervous system involvement is not present. There is also evidence for still unclassified forms. [ncbi.nlm.nih.gov]

nervous system involvement. [ncbi.nlm.nih.gov]

Merosin positive congenital muscular dystrophy with severe involvement of the central nervous system. [pubfacts.com]

Miller-Fisher Syndrome

However some features of the disease are still debated, particularly regarding possible central nervous system involvement. [moh-it.pure.elsevier.com]

nervous system involvement in the Miller Fisher syndrome. [journals.lww.com]

However there are occasional reports of central nervous system involvement. [ncbi.nlm.nih.gov]

Malignant Meningeal Lymphoma

PURPOSE: Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. [ncbi.nlm.nih.gov]

Korsager S, Laursen B, Mortensen TM: Dementia and central nervous system involvement in chronic lymphocytic leukemia. [link.springer.com]

Behçet Disease

A rare combination of both cerebral venous thrombosis and parenchymal central nervous system involvement was identified by neuroimaging. [ncbi.nlm.nih.gov]

Recurrent mucocutaneous lesions may be the only symptoms in mild cases, but articular, ocular, vascular, and/or gastrointestinal and central nervous system involvement may [ncbi.nlm.nih.gov]

Brain Central nervous system involvement is one of the most dangerous manifestations of Behcet’s. [hopkinsvasculitis.org]

Bloch Sulzberger Syndrome

How well a person does depends on the severity of central nervous system involvement and eye problems. [nlm.nih.gov]

nervous system involvement and eye problems. [ufhealth.org]

[…] www.ipif.org National Organization for Rare Disorders -- rarediseases.org/rare-diseases/incontinentia-pigmenti Outlook (Prognosis) How well a person does depends on the severity of central [ufhealth.org]

Spinal Pachymeningitis

nervous system involvement of AASV. [ncbi.nlm.nih.gov]

PMID: 19928692 IgG4-related sclerosing pachymeningitis: a previously unrecognized form of central nervous system involvement in IgG4-related sclerosing disease. [humpath.com]

Chan SK, Cheuk W, Chan KT, Chan JK (2009) IgG4-related sclerosing pachymeningitis: a previously unrecognized form of central nervous system involvement in IgG4-related sclerosing [springermedizin.de]

Rosai-Dorfman Disease

Central nervous system involvement is extremely rare, particularly cases with multiple intracranial masses. [ncbi.nlm.nih.gov]

Rosai-Dorfman disease with multiple lesions primarily involving the central nervous system is rare. [ncbi.nlm.nih.gov]

Central nervous system (CNS) involvement is infrequent and typically manifests as an isolated lesion. [ncbi.nlm.nih.gov]

Mitochondrial Complex 3 Deficiency Nuclear Type 1

OBJECTIVE To report a rare manifestation of CoQ(10) deficiency with isolated mitochondrial myopathy without central nervous system involvement. [unboundmedicine.com]

Cancer and the Central Nervous System Involvement E-2292 134 Posttreatment Neurologic Sequelae of Pediatric Central Nervous System Tumors E-2297 135 Muscle and Nerve Development [books.google.com]

OBJECTIVE: To report a rare manifestation of CoQ(10) deficiency with isolated mitochondrial myopathy without central nervous system involvement. [unboundmedicine.com]

Tuberculosis of Nervous System

Abstract The incidence of tuberculosis in the United States is increasing in all age groups; 5% of all of these patients have central nervous system involvement. [ncbi.nlm.nih.gov]

Do Not Do Recommendation For people with HIV (human immunodeficiency virus) and active TB (tuberculosis)without central nervous system involvement, do not routinely extend [nice.org.uk]

Central nervous system involvement is one of the most serious forms of this infection, acting as a prominent cause of morbidity and mortality in developing countries. [journals.lww.com]

Hemophagocytic Lymphohistiocytosis

The presence of central nervous system involvement has a profound impact on the prognosis, treatment, and clinical outcome of the disease. [ncbi.nlm.nih.gov]

These subdural effusions were the only objective documentations of central nervous system involvement, along with an increased cerebrospinal fluid protein level. [ncbi.nlm.nih.gov]

Diagnosis is challenging because it mimics severe sepsis by demonstrating hepatomegaly, splenomegaly, persistent fever, central nervous system involvement, and cytopenias. [ncbi.nlm.nih.gov]

Leptomeningeal Metastasis

Non-Hodgkin's lymphoma which occasionally involves the central nervous system, occurs more often in high-grade cases and implicates a poor prognosis. [ncbi.nlm.nih.gov]

Central nervous system involvement is unusual and particularly the occurrence of leptomeningeal metastasis (LM) is extremely rare, with few cases described in the medical [ncbi.nlm.nih.gov]

High-dose therapy with hematopoietic cell transplantation for patients with central nervous system involvement by non-Hodgkin's lymphoma. [link.springer.com]

Juvenile Xanthogranuloma

Solitary lesions in the spinal column are an especially rare presentation of this disease, and central nervous system involvement can portend a poor prognosis. [ncbi.nlm.nih.gov]

Central nervous system involvement is a poor prognostic factor. [ncbi.nlm.nih.gov]

Less commonly JXG may involve locations such as the lung, liver, adrenal gland, appendix, bones, bone marrow, pituitary gland, central nervous system, kidney, heart, small [histio.org]

Cerebral Angiitis

licensee BioMed Central Ltd. 2012 Received: 7 February 2012 Accepted: 15 May 2012 Published: 13 September 2012 Abstract Introduction Central nervous system involvement [jmedicalcasereports.biomedcentral.com]

References 1 An unusual central nervous system involvement in rheumatoid arthritis: combination of pachymeningitis and cerebral vasculitis, Rheumatol Int, 2009, vol. 29 (pg [academic.oup.com]

[Isolated vasculitis of the central nervous system and involvement of the 8th cranial nerve: rare manifestations of acquired immunodeficiency syndrome]. [frontiersin.org]

Whipple Disease

A subset of patients with the disease may either initially have or eventually develop symptoms of central nervous system involvement. [ncbi.nlm.nih.gov]

Long-term antibiotic therapy is required, and relapses are common, especially with central nervous system involvement. [ncbi.nlm.nih.gov]

Prognosis Untreated WD is relentlessly progressive and leads to death either by wasting or by central nervous system involvement. [orpha.net]

Neurosyphilis

[…] in central nervous system (CNS) disorders. [ncbi.nlm.nih.gov]

Central nervous system involvement by this infection is referred to as neurosyphilis. [docneuro.com]

There is evidence for neurosyphilis being associated with the central nervous system vasculitis involving medium and small vessels. [ncbi.nlm.nih.gov]

Central European Encephalitis

Magnetic resonance imaging (MRI) of the patient's cranium and spine revealed characteristic central nervous system involvement. [ncbi.nlm.nih.gov]

A small proportion have a monophasic illness, which usually has central nervous system involvement. [patient.info]

[…] case of TBE reported in the central part of Hokkaido Island, and describe the fatal clinical course of a patient who presented with meningoencephalomyelitis, which partly involved [ncbi.nlm.nih.gov]

Kerosene Poisoning

Others features noted were central nervous system involvement (14.5%), vomiting (20%), and fever 16 (29.1%). There were 3 deaths giving the mortality of 5.5%. [ncbi.nlm.nih.gov]

[…] kerosene on the central nervous system. [ncbi.nlm.nih.gov]

All patients with central nervous system complications had severe pulmonary involvement, suggesting a close relationship between the severity of pulmonary involvement and [ncbi.nlm.nih.gov]