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40 Possible Causes for Central Retinal Pigment Epithelium Changes

  • Familial Adenomatous Polyposis

    Congenital hypertrophy of the retinal pigment epithelium (CHRPE). These are benign pigment changes in the retina of your eye. Dental abnormalities.[mayoclinic.org] Rarely, FAP can cause cancer to develop in your thyroid gland, central nervous system, adrenal glands, liver or other organs. Noncancerous (benign) skin tumors.[mayoclinic.org]

  • Macular Dystrophy with Central Cone Involvement

    pigment epithelium and/or choroid changes, pale or atrophic peripapillary area, pale optic disk, relatively spared periphery, and slightly or moderately attenuated vessels[uniprot.org] […] area of the retina which provides detailed central vision) called drusen between the retinal pigment epithelium and the underlying choroid.[swvc.net] Subsequently, changes around the fovea develop, with a granular appearance of the retinal pigment epithelium (RPE).[atlasrleye.com]

  • Choroid Hemangioma

    change and pigmentation.[ncbi.nlm.nih.gov] Dilated fundus exam of the left eye ( Fig. 1 ) revealed a 2DD orange-red elevated lesion superior temporal to the optic nerve head with overlying retinal pigment epithelium[ncbi.nlm.nih.gov] An associated 3–4 DD central serous retinal detachment was also noted. Several ancillary tests were performed.[ncbi.nlm.nih.gov]

  • Retinal Detachment

    […] progressive retinal atrophy a disease of the retinal pigmented epithelium, generally in middle-aged Labrador retrievers, Border collies, Golden retrievers, Irish setters,[medical-dictionary.thefreedictionary.com] There are pigmentary changes in the tapetal fundus, with attenuation of retinal vasculature, and atrophy of the optic disk.[medical-dictionary.thefreedictionary.com] Retinal also combines with opsins in the retinal cones to form the three pigments responsible for color vision. retinal absence inherited as a recessive character in foals. central[medical-dictionary.thefreedictionary.com]

  • Serpiginous Choroiditis

    Despite anti-inflammatory treatment and successful macular hole surgery the visual function remained significantly impaired by secondary central retinal pigment epithelium[evidences.carpha.bvsalud.org] pigment epithelium.[bjo.bmj.com] changes.[evidences.carpha.bvsalud.org]

  • Retinal Telangiectasia

    Fifteen of 20 initially untreated eyes with type IIA IJRT developed either central retinal pigment epithelium membranes or subretinal neovascularization with loss of vision[journals.lww.com] Vision loss was caused by progressive telangiectatic changes and intraretinal edema.[journals.lww.com]

  • North Carolina Macular Dystrophy

    Grade II exhibits central confluent drusen with or without pigmentary changes, retinal pigment epithelium atrophy, disciform scar formation or neovascularization.[ophthalmicphotography.info] Subsequently, changes around the fovea develop, with a granular appearance of the retinal pigment epithelium (RPE).[atlasrleye.com] The clinical findings have been classified into different grades: In Grade I, fine drusen-like lesions at the level of the retinal pigmented epithelium are found in the central[ophthalmicphotography.info]

  • Toxic Retinopathy

    OCT (fig. 1 ) revealed subfoveal changes in the outer retina and the retinal pigment epithelium layer.[karger.com] No visual field or electrophysiology testing was performed; however, a visual field test performed by her optician was normal except for few central changes.[karger.com]

  • Central Serous Chorioretinopathy

    central visual acuity secondary to macular detachment Reduced central visual acuity secondary to progressive retinal pigment epithelium changes The main goal of the diagnostic[decisionmakerplus.net] On optical coherence tomography (OCT) we measured central retinal thickness (CRT), the outer nuclear layer (ONL), presence of subfoveolar detachment of retinal pigment epithelium[ncbi.nlm.nih.gov] Morphological changes in the retinal pigment epithelium of spectral domain OCT in the unaffected eyes with idiopathic central serous chorioretinopathy.[web.archive.org]

  • Spinocerebellar Ataxia Type 20

    Fundus examination showed mild retinal pigment epithelium (RPE) changes at the macula.[iovs.arvojournals.org] AF imaging showed a central hyperfluorescence. The 45 year old proband from family 2 had a visual acuity of 200/20 and dyschromatopsia.[iovs.arvojournals.org]

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