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163 Possible Causes for Central Scotoma, Optic Disc Pallor

  • Foster-Kennedy Syndrome

    The original description of the Foster Kennedy syndrome included the clinical triad of optic disc pallor in one eye, optic disc edema in the other eye, and reduced olfaction[ncbi.nlm.nih.gov] scotoma.[symptoma.com] An 11-year-old boy with a juvenile nasopharyngeal angiofibroma developed optic disc pallor in one eye and optic disc edema in the other eye (Foster Kennedy Syndrome [FKS])[ncbi.nlm.nih.gov]

  • Autosomal Dominant Optic Atrophy

    These patients typically present in the first decade of life with slightly subnormal acuity, dyschromatopsia, central visual field loss, and optic disc pallor.[practicalreviews.com] Early loss of inferior temporal RNFL in ADOA is related to superotemporal central scotoma.[ncbi.nlm.nih.gov] Humphrey visual field test shows cecocentral scotoma in right eye and central scotoma in left eye.[eyewiki.org]

  • Leber's Hereditary Optic Neuropathy

    Fundoscopic examination showed hyperemic papilla on the right eye and optic disc pallor on the left eye.[ncbi.nlm.nih.gov] The central scotoma gradually improved, and the visual acuity had recovered to 0.3 in August 2007.[ncbi.nlm.nih.gov] After subsequent development of bilateral optic disc pallor, we concluded that the patient had LHON. mtDNA analysis was conducted using non-radioisotopic single-strand conformational[ncbi.nlm.nih.gov]

  • Toxic Retinopathy

    disc pallor .[ejournalofophthalmology.com] (failure to see the dot suggests a central scotoma).[patient.info] disc pallor after few weeks to months. 16.[slideshare.net]

  • Primary Optic Atrophy

    Optic disc pallor is one of the defining characteristics of Dominant Optic Atropy.[webeye.ophth.uiowa.edu] scotoma OS Orthophoric Minimal amplitude horizontal pendular 10 CF 5′ CF 5′ 0 0 Diffuse optic atrophy OU Central scotomas OU Orthophoric None 11 20/200 20/100 Small discs[iovs.arvojournals.org] scotomas in the perimetry and pseudoedema of the optic disc, followed by optic atrophy.[link.springer.com]

  • Toxic Amblyopia

    Ophthalmoscopic changes are restricted at first to slight redness of the temporal margins of the optic discs; minimal pallor is observed at a later stage.[notesread.com] An initially small central or pericentral scotoma slowly enlarges, typically involving both the fixation and the blind spot (centrocecal scotoma), and progressively interferes[merckmanuals.com] pallor.[emedicine.medscape.com]

  • Papilledema

    Atropic Papilledema  Onset of optic disc pallor (secondary optic atrophy) .  Decrease in disc haemorrhage.  Narrowing of blood vessels and their ensheating.  Optic disc[slideshare.net] […] fields still showed persistent but incomplete binasal central scotomas.[surgicalneurologyint.com] disc elevation and blurred margins, but no hemorrhages or cotton wool spots In atrophic phase (optic nerve axons have died), optic disc shows mixture of pallor and swelling[kellogg.umich.edu]

  • Glaucoma

    disc pallor in humans. 1 - 5 Current pathophysiologic concepts of early glaucoma are based primarily on experimentally induced elevations of ocular pressure in laboratory[doi.org] Ophthalmological examination revealed 0.15 Snellen visual acuity, and fundoscopy revealed nearly total cupping and pallor of the optic disc and multiple retinal hemorrhagic[ncbi.nlm.nih.gov] The eye doctor will also look for other clues such as pallor (pale color), notches in the rim of the optic nerve head, small disc hemorrhages (blood on the edge of the nerve[emedicinehealth.com]

  • Optic Atrophy

    CONCLUSIONS: Deeply buried ODD may be associated with NAION causing irreversible visual loss and optic disc pallor, a condition easily mistaken for atypical ON.[ncbi.nlm.nih.gov] Symmetric thinned peripapillary RNFL was detected in the proband, whose visual field abnormalities were limited to central scotomas and were without mean deviation worsening[ncbi.nlm.nih.gov] Clinical features of ADOA include a slowly progressive bilateral loss of visual acuity, constriction of peripheral visual fields, central scotomas, and color vision abnormalities[ncbi.nlm.nih.gov]

  • Occlusion of the Ophthalmic Artery

    Detailed fundus examination in these patients showed a diffuse pallor of the optic disc with marked attenuation of arterioles and diffuse retinal pigmentary (RPE) changes,[ojoonline.org] Ophthalmoscopy revealed primary optic atrophy, arterial attenuation, mild pallor of the retina in the posterior pole, and a reddish-brown discoloration approximately two-third[healio.com] Figure 1: Color Fundus photograph (montage view) of the patient 1 (a) and patient 3 (b), showing the presence of diffuse disc pallor (asterisk), attenuated blood vessels ([ojoonline.org]

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