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42 Possible Causes for Central Sharp-and-Slow-Waves

  • Epilepsy

    EEG at 11 months showed right central high voltage slowing and sharp waves, and at 2.5 years, was unremarkable.[brain.oxfordjournals.org]

  • Ohtahara Syndrome

    EEG at 11 months showed right central high voltage slowing and sharp waves, and at 2.5 years, was unremarkable.[dx.doi.org]

  • Panayiotopoulos Syndrome

    The electroencephalogram manifestations are severe with long runs of high amplitude occipital sharp and slow waves.[adc.bmj.com] Although called centrotemporal spikes, these are mainly high amplitude sharp and slow wave complexes localised in the C3/C4 (high central) in 30 % of patients and C5/C6 (low[omicsonline.org] They often appear when the eyes are closed because they are activated by the elimination of fixation and central vision (fixation-off sensitivity). 4 6 7 Spikes in the centrotemporal[adc.bmj.com]

  • Rolandic Epilepsy

    Although called centrotemporal spikes, these are mainly high amplitude sharp and slow wave complexes localised in the C3/C4 (high central) in 30 % of patients and C5/C6 (low[omicsonline.org] The interictal EEG in Panayiotopoulos syndrome commonly reveals functional, mainly multifocal, high-amplitude sharp- and slow-wave complexes, with great variability at various[emedicine.com] It is important to perform a wake–sleep EEG because the spike-wave discharges are activated as the patient enters the sleep phase of the study.[omicsonline.org]

  • Brain Neoplasm

    Continuum (Minneap Minn). 2015 Apr;21(2 Neuro-oncology):480-6. doi: 10.1212/01.CON.0000464183.35322.5f. Abstract Neurologists are often on the front lines of diagnosis for primary and metastatic brain tumors. Patients with brain tumors typically have multiple comorbidities and pain generators beyond headache,[…][ncbi.nlm.nih.gov]

  • Angelman Syndrome

    EEG patterns in AS may show runs of slow wave activity over the frontal areas of the brain and sharp waves in this same area.[epilepsy.com] Slowing may also be seen most in the central and temporal regions of the brain; the central regions are involved in motor and sensory functions.[epilepsy.com]

  • Early Myoclonic Encephalopathy

    Inter-ictally, clusters of sharp-slow wave focal discharges maximum around the left Rolandic regions (left). They became continuous during natural sleep (right).[slideshare.net] Ictal discharge starts from the left central regions and rapidly spreads to the neighbouring regions.[slideshare.net]

  • Creutzfeldt Jakob Disease

    Prion diseases are unique transmissible neurodegenerative diseases that have diverse phenotypes and can be familial, sporadic, or acquired by infection. Recent findings indicate that the PrP genotype and the PrP(Sc) type have a major influence on the disease phenotype in both sporadic and familial human prion[…][ncbi.nlm.nih.gov]

  • Lennox-Gastaut Syndrome

    Review Article First Online: 09 November 2017 Abstract Lennox-Gastaut syndrome (LGS) is considered an epileptic encephalopathy and is defined by a triad of multiple drug-resistant seizure types, a specific EEG pattern showing bursts of slow spike-wave complexes or generalized paroxysmal fast activity, and[…][doi.org]

  • Miller Dieker Syndrome

    Summary Epidemiology MDS is undoubtedly a rare condition with a reported estimate of 1 cases per 100 000 live births, although incidence and prevalence are probably higher. Clinical description Children with MDS present with severe developmental delay, usually have epilepsy, and feeding problems are common. The[…][orpha.net]

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