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13 Possible Causes for Central Sharp-and-Slow-Waves, Paroxysmal Activity - Sharp-Waves

  • Epilepsy

    […] background, diffusemultifocal sharp waves and sharp waves-slow waves; paroxysmal fast activity Neurological examination mild diffuse hypotonia, mild ataxia with wide based[] wave located in the right central-parietal lobe.[] EEG at 11 months showed right central high voltage slowing and sharp waves, and at 2.5 years, was unremarkable.[]

  • Rolandic Epilepsy

    Although called centrotemporal spikes, these are mainly high amplitude sharp and slow wave complexes localised in the C3/C4 (high central) in 30 % of patients and C5/C6 (low[] The interictal EEG in Panayiotopoulos syndrome commonly reveals functional, mainly multifocal, high-amplitude sharp- and slow-wave complexes, with great variability at various[] It is important to perform a wake–sleep EEG because the spike-wave discharges are activated as the patient enters the sleep phase of the study.[]

  • Creutzfeldt Jakob Disease

    Sporadic Creutzfeldt-Jakob disease (sCJD) mainly occurs in the elderly, with the peak age of onset ranging from 55 to 75 years. The symptoms of sCJD are not unique, and laboratory tests such as magnetic resonance imaging (MRI), electroencephalogram (EEG) and cerebrospinal fluid (CSF)14-3-3 protein have low[…][]

  • Fragile X Syndrome

    Fragile-X syndrome (FXS) is a frequent genetic form of intellectual disability (ID). The main recurrent mutagenic mechanism causing FXS is the expansion of a CGG repeat sequence in the 5'-UTR of the FMR1 gene, therefore, routinely tested in ID patients. We report here three FMR1 intragenic pathogenic variants not[…][]

  • Angelman Syndrome

    EEG patterns in AS may show runs of slow wave activity over the frontal areas of the brain and sharp waves in this same area.[] The third pattern, 3–6 Hz activity punctuated by spikes and sharp waves in occipital leads, is associated with eye closure (C).[] Slowing may also be seen most in the central and temporal regions of the brain; the central regions are involved in motor and sensory functions.[]

  • Early Infantile Epileptic Encephalopathy Type 3

    ., multifocal spike- and sharp-wave discharges, repetitive paroxysmal activity, unusually low-voltage fast activity, and findings consistent with complex partial seizures[] Inter-ictally, clusters of sharp-slow wave focal discharges maximum around the left Rolandic regions (left). They became continuous during natural sleep (right).[] Ictal discharge starts from the left central regions and rapidly spreads to the neighbouring regions.[]

  • Lennox-Gastaut Syndrome

    Interictal EEG showed findings characteristic of LGS: generalized slow spike-wave complexes, multifocal sharp waves, generalized polyspikes and paroxysmal fast activity during[] In fact, 10/24 cases showed normal sleep transients with presence of symmetric vertex sharp waves in stage 1 non-REM sleep and also symmetric and well structured sleep spindles[] Also during sleep interictal background activity may be normal.[]

  • Benign Adult Familial Myoclonic Epilepsy

    The EEG in BRE has distinctive, high-amplitude, diphasic spikes or sharp waves with a prominent slow wave, in the midtemporal (T3, T4) and central (C3, C4) regions (Fig. 5[] Alvarez and Lombroso reported hypnagogic paroxysmal spike wave activity (minimal epileptiform features, sharp waves embedded into hyperventilation , or hypnagogic hypersynchrony[]

  • Benign Familial Infantile Epilepsy Type 4

    The EEG examination showed diffuse abnormal background activity, with sporadic isolated bilateral sharp waves over the occipital regions (a).[] The abnormal EEG findings that are most likely to correlate with clinical seizures include spikes or sharp waves, with or without concomitant slow waves, that are generalized[] The interictal EEG in Panayiotopoulos syndrome commonly reveals functional, mainly multifocal, high-amplitude sharp- and slow-wave complexes, with great variability at various[]

  • Postictal State

    For each seizure, the following elements were observed: 1) activity at seizure onset including spikes, sharp waves, desynchronization and irregular paroxysmal activity; 2)[] These discharges consisted of continuous spikes, sharp and slow waves that fluctuated in frequency and amplitude.[] Diffuse low amplitude slowing with frontocentral predominance was observed, in addition to central and symmetric spindles. No spikes or sharp waves were seen. Mr.[]

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