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714 Possible Causes for Cerebellar Atrophy Severe, Interictal Downbeat Nystagmus, Sensory Neuropathy (Less Prominent Feature)

Did you mean: Cerebellar Atrophy Severe, Interictal Downbeat Nystagmus, Sensory Neuropathy (Less Prominent Feature

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    Brain MRI showed severe cerebellar atrophy, prevalent in the vermis, with marked cortical atrophy of both hemispheres.[moh-it.pure.elsevier.com] . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] Other important signs include cervical spinal cord atrophy (in Friedreich’s ataxia and ataxia with vitamin E deficiency) and cerebellar and cerebral white-matter changes.[blogs.nejm.org]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Spinocerebellar Ataxia Type 6

    […] ataxia and cerebellar atrophy: both family 1 and 4 had severely ataxic patients, and cerebellar atrophy in one patient was found in five families.[academic.oup.com] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] Optic atrophy and epilepsy may be additional features. Laboratory findings Cerebellar atrophy varies from mild to severe and primarily involves the vermis.[emedicine.com]

  • Autosomal Recessive Spinocerebellar Ataxia 18

    SCAR18 features include progressive cerebellar atrophy, delayed psychomotor development, severely impaired gait, ocular movement abnormalities, and intellectual disability[malacards.org] SCAR20 is characterized by cerebellar atrophy, ataxia, coarsened facial features, severely delayed psychomotor development with poor or absent speech, and intellectual disability[genecards.org] […] ataxia-18 is a neurologic disorder characterized by delayed psychomotor development, severely impaired gait due to cerebellar ataxia, ocular movement abnormalities, and intellectual[malacards.org]

    Missing: Interictal Downbeat Nystagmus Sensory Neuropathy (Less Prominent Feature)
  • Early-Onset Cerebellar Ataxia

    Evidence of atrophy did not correlate with either the duration of illness or the severity of cerebellar ataxia in both the groups.[ncbi.nlm.nih.gov] . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] However, the child presented here has early onset progressive ataxia, speech delay, microcephaly, cerebellar atrophy and fundus albipunctatus.[ncbi.nlm.nih.gov]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Episodic Ataxia

    According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[dizziness-and-balance.com] Both patients showed severe cerebellar atrophy in MRI and clinical signs of progressive spinocerebellar atrophy type 6.[ncbi.nlm.nih.gov] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Acute Cerebellar Ataxia

    severe cerebellar atrophy 3 Laboratory findings CSF pleocytosis 4 Acute cerebellitis has been associated with a large number of infectious agents, such as: coxsackievirus[radiopaedia.org] . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] No further augmentation of ataxia or of cerebellar atrophy was observed during following 30 months.[ncbi.nlm.nih.gov]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Alcoholic Cerebellar Degeneration

    Normal brain stem (midbrain, pons and medulla are spared) Cerebellar Degeneration: Atrophy of the cerebellum is associated with many genetic conditions.[neuroradiologycases.com] . ; EA2 with interictal nystagmus , is long-lasting (hours) associated with attacks of vertigo, diffuse weakness, slurred speech, dystonia, seizures, truncal and limb ataxia[neuroweb.us] Large IV ventricle OPCA with slow saccades Ballooning of the IV ventricle "Molar tooth" deformity due to severe atrophy of the pons "Fine comb" atrophy of cerebellum OPCA[dizziness-and-balance.com]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Spastic Ataxia with Congenital Miosis

    Severe limb and gait ataxia were present in the 3 eldest patients. Two patients showed cerebellar atrophy on MRI.[findzebra.com] Optic atrophy and epilepsy may be additional features. Laboratory findings Cerebellar atrophy varies from mild to severe and primarily involves the vermis.[emedicine.medscape.com] Whether clinical severity correlates with amount of myelin deposited or degree of initial cerebellar atrophy has not yet been elucidated.[clinicalgate.com]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Autosomal Recessive Spinocerebellar Ataxia 8

    MR imaging revealed extensive cerebellar atrophy with “bat wing configuration” of the fourth ventricle in both patients. Severe cognitive impairment was not obvious.[mdsabstracts.org] According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[tchain.com] Optic atrophy and epilepsy may be additional features. Laboratory findings Cerebellar atrophy varies from mild to severe and primarily involves the vermis.[emedicine.medscape.com]

    Missing: Sensory Neuropathy (Less Prominent Feature)
  • Spinocerebellar Ataxia Type 4

    […] less severe than in patients with HD.[demneuropsy.com.br] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] Optic atrophy and epilepsy may be additional features. Laboratory findings Cerebellar atrophy varies from mild to severe and primarily involves the vermis.[emedicine.medscape.com]

    Missing: Sensory Neuropathy (Less Prominent Feature)