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29 Possible Causes for Cerebellar Gait Ataxia, Nocturnal Leg Cramp, Peripheral Neuropathy

  • Chronic Alcoholism

    The cause of the alcoholic gait is brain damage called alcoholic cerebellar ataxia.[promises.com] A consecutive sample of 62 chronic alcoholics was studied, 18 females and 44 males, aged between 28 and 69 years to assess the incidence and distribution of peripheral neuropathy[ncbi.nlm.nih.gov] The results show that alcohol-related neuropathy, especially when subclinical, seems to be frequent and mostly characterized by axonal degeneration of peripheral nerve fibres[ncbi.nlm.nih.gov]

  • Restless Legs Syndrome

    All patients have gait ataxia and the majority have lower limb ataxia.[dx.doi.org] Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[doi.org] Parkinsonism [adjusted odds' ratio (adj-OR) 7.4 (95% CI: 5.3-10.4)], peripheral neuropathy [adj-OR 3.7 (95% CI: 3.3-4.1)], subjective cognitive impairment (SCI) [adj-OR 3.1[ncbi.nlm.nih.gov]

  • Peripheral Neuropathy

    All patients have gait ataxia and the majority have lower limb ataxia.[doi.org] […] management of generic peripheral neuropathy.[doi.org] Nerve damage caused by injury can also be classified as peripheral neuropathy.[neuravite.com]

  • Pernicious Anemia

    It causes ataxia of stance and gait with relative sparing of the arms. It has an insidious onset and a subacute or chronic course.[neuropathology-web.org] Pernicious Anemia Macrocytic anemia, glossitis, peripheral neuropathy, weakness, hyperreflexia, ataxia, and other neurological manifestations characterize classical vitamin[clinlabnavigator.com] Cobalamin deficiency–related neurological impairment can vary in clinical presentation, including acute combined system degeneration, peripheral neuropathy, and psychosis.[emedicine.medscape.com]

  • Alcoholic Neuropathy

    Some people may experience frequent falls and gait unsteadiness due to ataxia.[en.wikipedia.org] Prognosis of alcoholic peripheral neuropathy.[jnnp.bmj.com] Limb or gait ataxia was prominent in 3 patients. Ataxia was of sensory type, and 1 patient additionally showed features of cerebellar ataxia.[jamanetwork.com]

  • Spastic Paraplegia

    Main inclusion criteria for HA were cerebellar gait and/or limb ataxia, and for HSP, spasticity in the lower limbs, brisk reflexes and positive Babinski sign [ 11, 12 ].[journals.plos.org] The aim of this study was to identify the genetic cause of the disease in an Italian family with spastic paraplegia and peripheral neuropathy.[ncbi.nlm.nih.gov] gait.[nature.com]

  • Autosomal Recessive Spastic Paraplegia Type 14

    The overall picture was spastic gait with variable associated distal wasting, sensory neuropathy and cerebellar ataxia ( Table 2 ).[academic.oup.com] She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years.[omicsonline.org] Type III patients present with cerebellar signs, and peripheral neuropathy. Type IV patients develop predominantly parkinsonism, and distal amyotrophy.[scielo.br]

  • Autosomal Recessive Spastic Paraplegia Type 18

    Other early signs of cerebellar ataxia include dysarthria and nystagmus. The spasticity is progressive and eventually dominates the clinical picture.[orpha.net] She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years.[omicsonline.org] The absence of a mutation, therefore, does not eliminate the possibility of a hereditary peripheral neuropathy.[mayomedicallaboratories.com]

  • Autosomal Recessive Spastic Paraplegia Type 46

    She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years.[omicsonline.org] Abstract Background: Hereditary cerebellar ataxias (HCA) and hereditary spastic paraplegias (HSP) are two groups of neurodegenerative disorders that usually present with progressive[karger.com] neuropathy, multiple sclerosis-like illness, spastic paraplegia or cataracts.[ncbi.nlm.nih.gov]

  • Autosomal Recessive Spastic Paraplegia Type 21

    Additional features including ataxia (gait and limbs), spastic dysarthria, dysphagia, pale optic disks, ataxia, nystagmus, strabismus, ptosis, hearing loss, motor and sensory[ncbi.nlm.nih.gov] She first noticed gait disturbance and spasticity in the lower extremities together with nocturnal leg cramps and pain attacks in the upper limbs at age of 28 years.[omicsonline.org] neuropathy.[asperbio.com]

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