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13 Possible Causes for Cerebral Edema, Diffuse Hepatic Steatosis, Hypoglycemia

  • Reye Syndrome

    In Reye-like syndrome, because of inborn errors of metabolism, hypoglycemia, hypoketonemia, elevated ammonia, and organic aciduria are often evident.[ncbi.nlm.nih.gov] Although cerebral edema is a nonspecific finding, it appears to be characteristic of Reye syndrome.[ncbi.nlm.nih.gov] Abstract Analysis of the liver histopathology in 19 children with clinical Reye syndrome (RS) revealed that nine had diffuse panlobular steatosis, one giant cell hepatitis[ncbi.nlm.nih.gov]

  • Citrullinemia Type 2

    Some previous studies [19,35,36] indicated that NICCD patients’ liver biopsies showed varying degrees of hepatic steatosis, diffuse hepatocyte microbubble degeneration, or[journals.lww.com] Head, ears, eyes, nose, and throat (HEENT): Papilledema may be present if cerebral edema and increased intracranial pressure have ensued.[checkorphan.org] Hypoglycemia and hypergalactosemia have also been reported as possible features of neonatal-onset CTLN2.[symptoma.com]

  • Hyperargininemia

    Some patients with documented hepatic dysfunction and fibrosis and/or steatosis have been reported, but the neurological features are always predominant (6,7).[journals.lww.com] Mannitol has been used but may not be as effective as hypertonic saline in alleviating cerebral edema due to hyperammonemia.[newenglandconsortium.org] Three days after birth, he was hospitalized for several days due to transient hypoglycemia. His developmental milestones were unremarkable before 1 year of age.[journals.lww.com]

  • Hepatitis

    Despite advances in intensive care management, mortality continues to be high (40–80%) and is partly related to ALF's complications, such as cerebral edema, sepsis, hypoglycemia[doi.org] diffusely decreased parenchymal attenuation on noncontrast CT diffuse edematous change hepatic steatosis may be a cause (steatohepatitis) or a result of acute hepatitis possible[radiopaedia.org] Patients with acute liver failure are at increased risk for hypoglycemia, which can be prevented by an intravenous glucose infusion.[doi.org]

  • Chronic Liver Disease

    Nocturnal hypoglycemia was seen in 22% of patients.[ncbi.nlm.nih.gov] An unusual case of acute cerebral edema as part of the syndrome of portal systemic encephalopathy in an individual with established chronic liver disease is reported.[ncbi.nlm.nih.gov] Cutoff values for grading steatosis varied across studies included in the meta-analysis but were not less than 25 % for moderate to severe hepatic steatosis.[link.springer.com]

  • Generalized Clonic or Tonic-Clonic Seizures

    .), sedative withdrawal in addicts (alcohol, barbiturates, benzodiazepines), hypoglycemia, hypoxia, and hyperthermia (especially before the age of 4).[dartmouth.edu] If not interrupted, it can lead to cerebral edema , a dangerous rise in body temperature, rhabdomyolysis , and cerebral cardiovascular failure![amboss.com] hepatic steatosis Abnormality of nervous system morphology CNS demyelination Decreased light- and dark-adapted electroretinogram amplitude Tapetoretinal degeneration Functional[mendelian.co]

  • Sudden Infant Death Syndrome

    Affected children typically present within the first 2 years of life with altered mental status and hypoglycemia brought on by periods of reduced nutritional intake associated[web.archive.org] BACKGROUND: Failure in the regulation of homeostatic water balance in the brain is associated with severe cerebral edema and increased brain weights and may also play an important[ncbi.nlm.nih.gov] Sixteen cases (7.3%) were associated with diffuse micro-vesicular or mixed micro- and macro-vesicular hepatic steatosis.[ncbi.nlm.nih.gov]

  • Liver Injury

    […] hypoattenuating, such as seen in steatosis , lacerations and haematomata may be more subtle to diagnose 8 .[radiopaedia.org] Causes of death in the absence of transplantation are mainly due to systemic infection and/or cerebral edema ( 40, 41 ).[gi.org] Diazoxide was discontinued with rapid resolution of the cardiorespiratory failure and without recurrence of hypoglycemia.[ncbi.nlm.nih.gov]

  • Chronic Persistent Hepatitis

    Despite advances in intensive care management, mortality continues to be high (40–80%) and is partly related to ALF's complications, such as cerebral edema, sepsis, hypoglycemia[doi.org] “bright liver” and with deep attenuation; and (3) “severe steatosis”, presence of diffusely severe “bright liver” and deep attenuation without visibility of the diaphragm[doi.org] Patients with acute liver failure are at increased risk for hypoglycemia, which can be prevented by an intravenous glucose infusion.[doi.org]

  • Chronic Hepatitis

    Despite advances in intensive care management, mortality continues to be high (40–80%) and is partly related to ALF's complications, such as cerebral edema, sepsis, hypoglycemia[doi.org] “bright liver” and with deep attenuation; and (3) “severe steatosis”, presence of diffusely severe “bright liver” and deep attenuation without visibility of the diaphragm[doi.org] Patients with acute liver failure are at increased risk for hypoglycemia, which can be prevented by an intravenous glucose infusion.[doi.org]

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