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1,037 Possible Causes for Cerebral Gliosis, Parkinson's Disease

  • Stroke

    Chronic Later still the residual swelling passes, and gliosis sets in eventually appearing as a region of low density with negative mass effect.[radiopaedia.org] Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study , A J Yarnall , R A Lawson , G W Duncan , T K Khoo , G S Petrides , J T O'Brien[jnnp.bmj.com] Recent findings Cholinesterase inhibitors improve attention, as well as memory, in several conditions including cortical Lewy body disease, Parkinson's disease dementia, traumatic[doi.org]

  • Amyotrophic Lateral Sclerosis

    […] widespread in the PNL and motor neuron systems and also in the amygdala and hippocampus where no significant gliosis or neuronal loss was detected.[ncbi.nlm.nih.gov] Amyotrophic lateral sclerosis (ALS) and Parkinson's disease, both progressive neurodegenerative diseases, affect 1 million Americans (1,2).[ncbi.nlm.nih.gov] Recent advances in patient neuroimaging have allowed direct visualization of neuroinflammation such as gliosis.[ncbi.nlm.nih.gov]

  • Progressive Supranuclear Palsy

    Microscopic observations showed extensive superficial spongiosis and severe neuronal loss with gliosis in the second and third cortical layers in the frontal, temporal and[ncbi.nlm.nih.gov] P/M, pons to midbrain ratio; PD, idiopathic Parkinson's disease; PSP-RS, Progressive Supranuclear Palsy-Richardson's Syndrome; Parkinson's disease; Progressive Supranuclear[ncbi.nlm.nih.gov] In addition, moderate to severe loss of neurons was found with gliosis and a lot of Gallyas/tau‐positive globus neurofibrillary tangles in the caudate nucleus, globus pallidus[doi.org]

  • Brain Neoplasm

    Cranial MRI showed a single, 4 cm mass associated with perilesional edema, contrast enhancement, and sometimes a shift of the contiguous cerebral tissue.[thefreelibrary.com] Disease: 13 people, 46.43% Osteoporosis (bones weak and more likely to break): 13 people, 46.43% Osteopenia (a condition where bone mineral density is lower than normal):[ehealthme.com] Each of these 9 patients had biopsy-proven demyelination, with relative preservation of axons and variable degrees of macrophage infiltration and reactive gliosis.[thefreelibrary.com]

  • Creutzfeldt Jakob Disease

    Gliosis and hypertrophic astrocytosis were generally mild in character. Neurons were relatively preserved in number.[ncbi.nlm.nih.gov] Jellinger KA (2000) Cell death mechanisms in Parkinson’s disease. J Neural Transm 107:1–29 PubMed CrossRef Google Scholar 32.[dx.doi.org] Extensive spongiform changes were observed in the cerebral neocortex, striatum, thalamus and cerebellar cortex, but gliosis was mild or absent.[ncbi.nlm.nih.gov]

  • Classic Progressive Supranuclear Palsy Syndrome

    Figure 2 Glial stained section through the midbrain of a patient with PSP showing midbrain atrophy with dilation of the cerebral aqueduct and gliosis of the substantia nigra[pmj.bmj.com] Neuropsychological characterization of typical and atypical progressive supranuclear palsy and comparison with Parkinson's disease.[minerva-access.unimelb.edu.au] In addition, severe fibrillary gliosis was noted in the precentral gyrus and corticospinal tract, being consistent with upper motor neuron syndrome observed in this case.[okayama.pure.elsevier.com]

  • Alzheimer Disease

    Multifocal spongiform encephalopathic changes, mononuclear perivascular infiltrates, subcortical demyelination and gliosis were also found.[ncbi.nlm.nih.gov] Parkinson's Disease Rating Scale; MMSE: Mini-Mental State Examination; PD: Parkinson disease; PDD: Parkinson disease dementia.[ncbi.nlm.nih.gov] AD brains contain numerous amyloid plaques surrounded by dystrophic neurites, and show profound synaptic loss, neurofibrillary tangle formation and gliosis.[ncbi.nlm.nih.gov]

  • Gaucher Disease Type 2

    […] was found in the dorsal part of the brainstem rather than the ventral part. (3) Neuronal cells in the superior olivary nucleus were lost, and marked gliosis was found in[cambridge.org] […] or Parkinson disease ( see nervous system disease: Diseases and disorders ).[britannica.com] Along with the presence of GCs, type 2 and 3 GD shows also neuronophagia, neuronal loss, and gliosis. No neuronal storage is seen.[neuropathology-web.org]

  • Cerebral Cortical Atrophy

    […] persistent inflammatory-demyelinating disease of the central nervous system (CNS), characterized pathologically by areas of inflammation, demyelination, axonal loss, and gliosis[ajnrdigest.org] […] to differentiate Parkinson's disease dementia and Parkinson's disease-normal cognition patients," the investigators wrote in conclusion.[medpagetoday.com] […] of PCA, however it has been described in associations with Huntingtons’ disease, Lewy body dementia, Creutzfeldt-Jakob disease, cortico-basal degeneration and subcortical gliosis[omicsonline.org]

  • Olivopontocerebellar Atrophy

    The nucleus basalis of Meynert had numerous NFTs with fibrillary gliosis and neuronal cell loss.[ncbi.nlm.nih.gov] Abstract Nine Parkinson's disease (PD), seven olivopontocerebellar atrophy (OPCA) patients and two age-matched control groups learned a linear arm movement-scaling task over[ncbi.nlm.nih.gov] , and also how a favorable response to levodopa is neither synonymous with idiopathic Parkinson's disease, nor does it exclude multiple-system, atrophy-related parkinsonism[ncbi.nlm.nih.gov]

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