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198 Possible Causes for Cerebral Thrombosis, Hyperuricemia, Poor Outcome

  • Hypertension

    , and renal vascular resistance), and from decreased blood flow and ischemia ( myocardial infarction, cerebral thrombosis and infarction, and renal nephrosclerosis).[britannica.com] Patients with resistant hypertension are also at higher risk for poor outcomes, particularly those with certain comorbidities (eg, chronic kidney disease, ischemic heart disease[emedicine.medscape.com] Epidemiological and experimental studies suggest a linkage between hyperuricemia and hypertension. Hyperuricemia affects 25-40 % of patients with untreated hypertension.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    […] clinical outcomes of both ischemic and hemorrhagic strokes.[ncbi.nlm.nih.gov] Fructose is also the only sugar able to increase blood uric acid concentrations, and SSB consumption has been linked to development of hyperuricemia (serum uric acid level[doi.org] Hypothesis: fructose-induced hyperuricemia as a causal mechanism for the epidemic of the metabolic syndrome. Nat Clin Pract Nephrol. 2005 ; 1 : 80–86.[doi.org]

  • Arteriosclerosis

    […] include vasospasm, thrombosis, and accelerated atherosclerosis.[ncbi.nlm.nih.gov] Poor operative candidates underwent delayed formalization to allow for preoperative optimization.[ncbi.nlm.nih.gov] IL-8/CXCR2 While high levels of circulating chemokines are associated with poor outcome, they contribute towards deactivating circulating leukocytes and limiting their recruitment[physrev.physiology.org]

  • Myeloproliferative Disease

    […] for deep vein thrombosis.[ncbi.nlm.nih.gov] The outcome for pregnancy in ET appears to be relatively poor with a successful live birth rate of 50-57%.[npeu.ox.ac.uk] […] leukemia and agnogenic myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to gouty arthritis that is secondary to hyperuricemia[emedicine.com]

  • Polycythemia Vera

    […] arteries, veins and dural sinuses (may mimic cerebral vein thrombosis ) splenic infarction venous thromboses acute superior mesenteric venous thrombosis dural venous sinus[radiopaedia.org] outcomes.[mpncanada.com] Increased cell turnover may cause hyperuricemia, increasing the risk of gout and urate kidney stones.[merck.com]

  • Waldenstrom Macroglobulinemia

    Sometimes cerebral thrombosis, lymphadenopathy, hepatosplenomegaly, and renal disease, particularly proliferative glomerulonephritis may be present.[haematologica.org] Seite 47 - Defining Molecular Profiles of Poor Outcome in Patients With Invasive Bladder Cancer Using Oligonucleotide Microarrays. J Clin Oncol, 24, pp. ‎[books.google.de] Results Engraftment and toxicity Of the four patients receiving autograft, one died on day 30 from a cerebral artery thrombosis.[doi.org]

  • Sickle Cell Disease

    However, chronic transfusion therapy is indicated for prevention of recurrent cerebral thrombosis, especially in children, in an effort to maintain the Hb S percentage less[msdmanuals.com] Their outcomes were uniformly poor: 4 died (age range, 12 mo-17 yr); 3 had documented cerebrovascular accidents; and 3 developed ventricular dysfunction.[ncbi.nlm.nih.gov] Headache, paralysis, and convulsions may result from cerebral thrombosis, which can cause stroke, blindness, and other neurological disturbances.[medical-dictionary.thefreedictionary.com]

  • Essential Hypertension

    The question frequently arises whether the neurological symptoms are caused by cerebral hemorrhages as a result of rupture of diseased vessels, encephalomalacias from thrombosis[annals.org] Patients with resistant hypertension are also at higher risk for poor outcomes, particularly those with certain comorbidities (eg, chronic kidney disease, ischemic heart disease[emedicine.medscape.com] Mild hyperuricemia induces glomerular hypertension in normal rats. Am J Physiol 2002; 283 : F1105–F1110. 15.[doi.org]

  • Preeclampsia

    A 26 year old primigravida with preeclampsia was diagnosed with a cerebral venous thrombosis 6 days following Cesarean section.[ncbi.nlm.nih.gov] Inequalities in access to adequate prenatal care may contribute to poor outcomes associated with preeclampsia in African American women.[ncbi.nlm.nih.gov] Uric acid values can be quite helpful in such situations, since hyperuricemia is uncommon in pregnancy except with gout, renal failure, or preeclampsia-eclampsia. —————- Treatment[health.am]

  • Chronic Kidney Insufficiency

    […] haemorrhage, while other patients experience a prothrombotic status associated with an increased number of cardiovascular events or recurrent thrombosis of the dialysis access[academic.oup.com] Therefore, patients who suffer ACRF with high levels of baseline proteinuria are at particular risk for poor outcomes.[clinicaladvisor.com] This latter approach is associated with poor patient outcomes and high costs.[nature.com]

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