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1,713 Possible Causes for Cerebrospinal Fluid Abnormality, Corneal Infiltrate, Free-Living Ameba Infection

  • Primary Amebic Meningoencephalitis

    Clinicians: CDC no longer provides miltefosine for treatment of free-living ameba infections. Miltefosine is now commercially available.[cdc.gov] Cerebrospinal fluid (CSF) cell count and chemistries were markedly abnormal, with a white blood cell count of 8150 cells/mm 3 (90% neutrophils), red blood cell count of 800[academic.oup.com] Cerebrospinal fluid (CSF) opening pressure was 380 mmH 2 O.[ruralneuropractice.com]

    Missing: Corneal Infiltrate
  • Acanthamoeba Keratitis

    Epidemiology of free-living ameba infections. J Protozool 1990;37(4):25S-33S. van Flink F et al.[webeye.ophth.uiowa.edu] It typically presents as a unilateral central or paracentral corneal infiltrate, often with a ring-shaped peripheral infiltrate.[ncbi.nlm.nih.gov] This infection is caused by a microscopic, free-living ameba (single-celled living organism) called Acanthamoeba.[cdc.gov]

    Missing: Cerebrospinal Fluid Abnormality
  • Keratitis

    Source : AAO Acanthamoeba keratitis Causes This infection is caused by a microscopic, free-living ameba (single-celled living organism) called Acanthamoeba.[provisu.ch] Adenoviral conjunctivitis may lead to subepithelial corneal infiltrates as a late complication.[ncbi.nlm.nih.gov] He had undergone a corneal tear repair on that eye 15 days prior to the onset of keratitis. The infiltrations were along the sutured corneal tear tracts.[ncbi.nlm.nih.gov]

    Missing: Cerebrospinal Fluid Abnormality
  • Meningitis

    Primary amebic meningoencephalitis (PAM) is a rare but nearly always fatal disease caused by infection with Naegleria fowleri, a thermophilic, free-living ameba found in freshwater[cdc.gov] fluid abnormalities.[doi.org] Naegleria fowleri is a free-living microscopic ameba that lives in warm water and soil.[cdc.gov]

    Missing: Corneal Infiltrate
  • Lyme Meningoencephalitis

    Infection with free-living amebas is an infrequent but often life-threatening human illness, even in immunocompetent individuals.[emedicine.medscape.com] Moderate pleocytosis and increased albumin can be found in the cerebrospinal fluid; abnormalities in the thalamus, cerebellum, and brainstem in MRI may be shown as well.[columbia-lyme.org] fluid abnormalities in the form of lymphocytic pleocytosis indicating blood-brain barrier damage.[lyme-symptoms.com]

    Missing: Corneal Infiltrate
  • Neonatal Meningitis

    Infection with free-living amebas is an infrequent but often life-threatening human illness, even in immunocompetent individuals.[emedicine.com] Abnormal cerebrospinal fluid (CSF) parameters are often used to predict neonatal meningitis and determine length and type of antibiotic therapy in neonates with a positive[ncbi.nlm.nih.gov]

    Missing: Corneal Infiltrate
  • Histoplasma Meningitis

    Infection with free-living amebas is an infrequent but often life-threatening human illness, even in immunocompetent individuals.[emedicine.medscape.com] Lumbar puncture (LP) See separate articles Lumbar Puncture and Cerebrospinal Fluid for normal values and interpretation of abnormal CSF findings.[patient.info] Repeated lumbar punctures for cerebrospinal fluid analysis should be done to determine the response to therapy and should assess Histoplasma antigen levels, white blood cell[cmr.asm.org]

    Missing: Corneal Infiltrate
  • Legionella Meningoencephalitis

    "Chapter 6: Free Living Amebae". Diagnostic Pathology of Parasitic Infections with Clinical Correlations (2 ed.). USA: Oxford University Press. pp. 114–115.[en.wikipedia.org] Investigational drug available directly from CDC for the treatment of infections with free-living amebae. MMWR Morb Mortal Wkly Rep 2013;62:666. [Table 1][neurologyindia.com] ; CSF Gram stain (bacteria), acid-fast (mycobacteria), India ink (Cryptococcus), wet prep (free-living amebae), & Giemsa (trypanosomes); PCR (highly sens/spec) for HSV, CMV[quizlet.com]

    Missing: Corneal Infiltrate
  • Eosinophilic Meningoencephalitis

    Clin Infect Dis . 2016 Mar 15. 62 (6):774-6. [Medline] . Investigational Drug Available Directly from CDC for the Treatment of Infections with Free-Living Amebae.[emedicine.medscape.com] Cerebrospinal fluid abnormalities were similar to alert patients with eosinophilic meningitis.[ncbi.nlm.nih.gov] Magnetic resonance imaging (MRI) scans of his brain and spine showed no abnormality. His cerebrospinal fluid (CSF) was acellular, with normal glucose and protein levels.[mja.com.au]

    Missing: Corneal Infiltrate
  • Cerebral Thrombosis

    Examination of the cerebrospinal fluid (CSF) does not necessarily help in establishing the diagnosis as there are no pathognomonic features.[pmj.bmj.com] Lumbar Puncture Unless there is clinical suspicion of meningitis, examination of the cerebrospinal fluid (CSF) is typically not helpful in cases with focal neurological abnormalities[stroke.ahajournals.org] Abnormalities are found in up to 84% of cases and include raised CSF pressure, increased protein content, the presence of red blood cells and pleocytosis. 5 Nevertheless,[pmj.bmj.com]

    Missing: Corneal Infiltrate Free-Living Ameba Infection