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1,467 Possible Causes for Cerebrospinal Fluid Abnormality, EMG Shows Neurogenic Abnormalities, Facial Muscle Weakness and Progressive Atrophy

  • Amyotrophic Lateral Sclerosis

    EMG change were at an earlier stage of evolution than those showing severe weakness and marked neurogenic EMG change.[doi.org] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] Cerebrospinal fluid (CSF) testing revealed no abnormalities except for an elevated neopterin concentration at 143.17 pmol/mL (normal 30 pmol/mL).[ncbi.nlm.nih.gov]

  • Leigh's Disease

    EMG of the anterior tibialis muscle showed signs of both neurogenic and muscular involvement. MNCV of the peroneal and median nerve was slowed.[ajnr.org] There also tends to be a high level of a chemical called lactic acid in the fluid round the brain called the cerebrospinal fluid (CSF).[contact.org.uk] In addition, one or more of the following conditions is present: block of electrical signals in the heart (cardiac conduction defects) elevated cerebrospinal fluid protein[umdf.org]

    Missing: Facial Muscle Weakness and Progressive Atrophy
  • Distal Spinal Muscular Atrophy Type 3

    Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] Bulbar muscular atrophy affects the bulbar and facial muscles with motor neurone loss in the brainstem. [ 1 ] The spinal muscular atrophies (SMAs) are a spectrum of genetically[patient.info] They all result in progressive lower motor neurone weakness. The gene defect is on chromosome 5q and the implicated gene is called survival motor neurone gene 1 (SMN1).[patient.info]

    Missing: Cerebrospinal Fluid Abnormality
  • Kearns-Sayre Syndrome

    PEO6 DNA2 AD PEO w/variable, slowly progressive features; onset: childhood-adulthood Slender build Facial muscle weakness; exertional dyspnea; obstructive sleep apnea; myopathy[ncbi.nlm.nih.gov] […] high protein content in the cerebrospinal fluid (more than 100mg/dL), and markedly reduced activity of enzymes involved in the respiratory chain complex, such as citrate[symptoma.com] We suggest that mitochondrial abnormalities due to the presence of abundant Delta-mtDNAs in the choroid plexus play an important role in causing the increased cerebrospinal[ncbi.nlm.nih.gov]

    Missing: EMG Shows Neurogenic Abnormalities
  • Spinal Muscular Atrophy Type 1

    We present a baby with spinal muscular atrophy type 1, an inherited disorder causing progressive weakness, leading to complete paralysis of respiratory, facial and limb muscles[ncbi.nlm.nih.gov] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] Bulbar muscular atrophy affects the bulbar and facial muscles with motor neurone loss in the brainstem. [ 1 ] The spinal muscular atrophies (SMAs) are a spectrum of genetically[patient.info]

    Missing: Cerebrospinal Fluid Abnormality
  • Spinal Muscular Atrophy Type 4

    Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] Scapuloperoneal spinal muscular atrophy: Type 1 (AD form) appears at age 14-26, with weakness, distal leg atrophy, and absent tendon reflexes and sparing of intrinsic foot[emedicine.medscape.com] Bulbar muscular atrophy affects the bulbar and facial muscles with motor neurone loss in the brainstem. [ 1 ] The spinal muscular atrophies (SMAs) are a spectrum of genetically[patient.info]

    Missing: Cerebrospinal Fluid Abnormality
  • Spinal Muscular Atrophy Type 2

    Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] Bulbar muscular atrophy affects the bulbar and facial muscles with motor neurone loss in the brainstem. [ 1 ] The spinal muscular atrophies (SMAs) are a spectrum of genetically[patient.info] They all result in progressive lower motor neurone weakness. The gene defect is on chromosome 5q and the implicated gene is called survival motor neurone gene 1 (SMN1).[patient.info]

    Missing: Cerebrospinal Fluid Abnormality
  • Cerebral Thrombosis

    Examination of the cerebrospinal fluid (CSF) does not necessarily help in establishing the diagnosis as there are no pathognomonic features.[pmj.bmj.com] Lumbar Puncture Unless there is clinical suspicion of meningitis, examination of the cerebrospinal fluid (CSF) is typically not helpful in cases with focal neurological abnormalities[stroke.ahajournals.org] Abnormalities are found in up to 84% of cases and include raised CSF pressure, increased protein content, the presence of red blood cells and pleocytosis. 5 Nevertheless,[pmj.bmj.com]

    Missing: EMG Shows Neurogenic Abnormalities Facial Muscle Weakness and Progressive Atrophy
  • Chronic Fatigue Syndrome

    […] immune signatures in plasma and cerebrospinal fluid [ 16, 17 ].[dx.doi.org] […] immune signatures in plasma and cerebrospinal fluid [ 16 , 17 ].[microbiomejournal.biomedcentral.com] Abnormal immune activation can be caused by translocation of microbes from an inflamed gut [ 18 ].[dx.doi.org]

    Missing: EMG Shows Neurogenic Abnormalities Facial Muscle Weakness and Progressive Atrophy
  • Stroke

    Beyond F.A.S.T. – Other Symptoms You Should Know Sudden NUMBNESS or weakness of face, arm, or leg, especially on one side of the body Sudden CONFUSION, trouble speaking or understanding speech Sudden TROUBLE SEEING in one or both eyes Sudden TROUBLE WALKING, dizziness, loss of balance or coordination Sudden[…][strokeassociation.org]

    Missing: EMG Shows Neurogenic Abnormalities Facial Muscle Weakness and Progressive Atrophy