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21 Possible Causes for Cerebrospinal Fluid Abnormality, Focal Neurologic Deficit, Frontal Intermittent Rhythmic Delta Activity

  • Stroke

    Awakening with or experiencing the abrupt onset of focal neurologic deficits is the hallmark of ischemic stroke diagnosis.[] In most cases, it occurs in a rhythmic and intermittent manner, and the most commonly and important types are frontal intermittent rhythmic delta activity (FIRDA) ( Fig 2[] The literature documents numerous case reports of patients presenting with focal neurological deficits subsequently attributed to hypoglycaemia.[]

  • Subarachnoid Hemorrhage

    Spinal SAH alone rarely causes focal neurologic deficit.[] […] for SAH; CT negative for SAH and inconclusive cerebrospinal fluid examination.[] neurological deficits such as hemiparesis, sensory loss, or aphasia.[]

  • Subdural Hematoma

    Six percent of patients presented with radiculating pain without any focal neurological deficits.[] He has no focal neurological deficits, but appears confused when responding to your questions. His CT scan is shown in Figure A.[] She returned to baseline after each seizure, had no obvious signs of trauma, and did not exhibit any focal neurologic deficits.[]

  • Brain Neoplasm

    Neurological deficit and progressive, focal, or general headaches (in large tumours) are common. Tumours may also produce visible bony growth.[] For example, blood and cerebrospinal fluid may also be tested to check for substances secreted by tumors (called tumor markers) and for gene abnormalities that are characteristic[] 3 months; new parictal lesion. deficits and with mass effect abnormalities; Dx: MS BAEP Brain stem auditory evoked potential, CC corpus callosum, CSF cerebrospinal fluid,[]

  • Cerebral Hemorrhage

    Nausea, vomiting, delirium, and focal or generalized seizures are also common. Neurologic deficits are usually sudden and progressive.[] Cerebrospinal fluid (CSF) studies disclosed mononuclear pleocytosis with elevated protein levels.[] Results of a polymerase chain reaction assay of the cerebrospinal fluid were positive for HSV-1. His course was complicated by 2 episodes of cerebral hemorrhage.[]

  • Neurosyphilis

    In patients with dementia paralytica, it is also associated with seizures, exacerbation of preexisting psychosis, or the development of focal neurological deficits [ 5 ].[] A diagnosis of neurosyphilis should be considered in patients with serologic evidence of syphilis and one or more of the following cerebrospinal fluid abnormalities; mononuclear[] Physical examination was normal and there was no focal neurological deficit or signs of cognitive impairment, apart from mild expressive dysphasia.[]

  • Cerebral Neoplasm

    Progressive focal neurological deficits - eg, diplopia associated with a cranial nerve defect, visual field defect, neurological deficits affecting the upper and/or lower[] This is a sac of cerebrospinal fluid (CSF), which has been "trapped" outside or inside the brain. It might also be called a "leptomeningeal cyst."[] Symptoms of meningiomas may include any of the following: Headaches Seizures Change in personality or behavior Progressive focal neurologic deficit Confusion Drowsiness Hearing[]

  • Susac Syndrome

    A 23 year-old female presented to a neurology department with a 3 year history of recurrent episodes involving hearing loss, encephalopathy, focal neurological deficits, and[] Cerebrospinal fluid was abnormal in 5 patients showing pleocytosis (mean, 24.6; range, 6-85 cells/mL) and elevated protein level (mean, 210; range, 113-365 mg/dL).[] The EEG showed frontal intermittent rhythmic delta activity.[]

  • Progressive Multifocal Leukoencephalopathy

    Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening disease that is characterized by focal neurological deficits.[] Diagnosis of PML was done on basis of clinical and radiological abnormalities highly suggestive of the condition, with or without confirmation of JCV DNA in the cerebrospinal[] PML causes rapidly progressive focal neurological deficits including: cognitive and behavioural changes; paraesthesia; visual problems; gait abnormalities and loss of limb[]

  • Metabolic Encephalopathy

    She has no focal neurological deficits.[] The cerebrospinal fluid can also be analyzed for abnormal proteins, chemicals, and cells.[] […] patterns, e.g., frontal intermittent rhythmic delta activity (FIRDA), or spikes and sharp waves as well as spike-wave discharges in temporal regions. [37] In hyponatremia[]

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