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61 Possible Causes for Cerebrospinal Fluid Abnormality, primarily in the legs, severe muscle wasting

Did you mean: Cerebrospinal Fluid Abnormality, primarily in the legs, severe, muscle wasting

  • Amyotrophic Lateral Sclerosis

    Excluding lower motor neuron FA and FL cases, progressive muscular atrophy comprised 4% of the sample and had a prognosis similar to typical limb onset ALS.[ncbi.nlm.nih.gov] Cerebrospinal fluid (CSF) testing revealed no abnormalities except for an elevated neopterin concentration at 143.17 pmol/mL (normal 30 pmol/mL).[ncbi.nlm.nih.gov] […] by often asymmetric and primarily distal LMN involvement in the lower limbs.[doi.org]

  • Syringomyelia

    Syringomyelia is marked clinically by pain and paresthesia, followed by muscular atrophy of the hands and analgesia with thermoanesthesia of the hands and arms, but with the[medical-dictionary.thefreedictionary.com] To the Editor: Syringomyelia is a condition with various causes in which fluid accumulates in an abnormal cavity within the spinal cord.[nejm.org] Extension of the syrinx into the lumbar region and involvement of the legs.[patient.info]

  • Syringobulbia

    atrophy : Werdnig-Hoffman - Kugelberg-Welander - Fazio Londe - MND ( ALS, PMA, PBP, PP, PLS ) Extrapyramidal and movement disorders Parkinson's disease - Neuroleptic malignant[wikidoc.org] Aetiology A blockage in the circulation of cerebrospinal fluid (CSF) is the most common cause of syringomyelia.[patient.info] As a result, lack of nerve sensation and muscular atrophy typically occur. In about half of the cases, the disorder is present at birth (congenital).[nmihi.com]

  • Powassan Encephalitis

    Complications of Powassan virus disease may include permanent problems such as recurrent headaches, muscle wasting, and memory problems; severe infections may cause death[medicinenet.com] Moderate pleocytosis and increased albumin can be found in the cerebrospinal fluid; abnormalities in the thalamus, cerebellum, and brainstem in MRI may be shown as well.[columbia-lyme.org] The black legged tick (I. scapulars) is the primary vector known to transmit Powassan virus to humans in the US and is not known to occur in Colorado.[coloradoticks.org]

  • Cushing's Disease

    RESULTS: Hirsutism, plethora facial, muscular weakness and muscular atrophy were more frequent in the MIC patients.[ncbi.nlm.nih.gov] […] and electrolyte abnormalities (276.0–276.9), iatrogenic panhypopituitarism (253.7), and cerebrospinal fluid rhinorrhea (349.81).[doi.org] […] in the abdomen, with relative thinning of the arms and legs, and abdominal stretch marks.[massgeneral.org]

  • Restless Legs Syndrome

    Linkage disequilibrium analysis of childhood-onset spinal muscular atrophy (SMA) in the French-Canadian population.[dx.doi.org] Iron homeostasis abnormalities have been implicated through cerebrospinal fluid (CSF) iron profile measures.[emedicine.com] "An urge to move, usually due to uncomfortable sensations that occur primarily in the legs, but occasionally in the arms or elsewhere."[en.wikipedia.org]

  • Amyloidosis

    The presence of Val30Met mutation strongly predicts for peripheral neuropathy, autonomic neuropathy, and abnormalities in the cerebrospinal fluid, whereas patients with the[bloodjournal.org] Amyloid protein deposits often occur primarily in the kidneys and can cause protein in the urine, swelling of the legs and feet and fatigue.[froedtert.com]

  • Neuropathy

    Types I and II (varieties of Charcot-Marie-Tooth disease, also called peroneal muscular atrophy) are the most common; they are usually autosomal dominant disorders but can[merckmanuals.com] fluid (CSF) analysis – to detect abnormalities or infections in the central nervous system Specific tests for autoimmune disorders, such as antinuclear antibody (ANA) Specific[labtestsonline.org] , such as Charcot-Marie-Tooth disease You may need a lumbar puncture to test the cerebrospinal fluid (a clear, colourless fluid that surrounds and supports the brain and spinal[nhsdirect.wales.nhs.uk]

  • Spastic Quadriplegic Cerebral Palsy Type 2

    […] palsy G1229Other motor neuron disease G128Other spinal muscular atrophies and related syndromes G129Spinal muscular atrophy, unspecified G320Subacute combined degeneration[cms.gov] Studies of cerebrospinal fluid revealed normal cell counts and levels of protein and glucose but an elevated level of IgG of 0.077 g per liter (normal, 0.01 to 0.03) and an[nejm.org] It primarily affects the legs although there can be some upperbody involvement in some individuals.[en.wikipedia.org]

  • Limb-Girdle Muscular Dystrophy Type 1E

    ATROPHIES & MOTOR NEURON DISEASES Spinal muscular atrophy, type I-IV (SMN1) Spinal muscular atrophy, autosomal dominant, proximal, adult-onset (VAPB) Spinal muscular atrophy[meduniwien.ac.at] Affected individuals also have obstructive hydrocephalus, a condition in which blockage of the normal circulation of cerebrospinal fluid results in pressure on the brain.[rarediseases.org] Affected individuals also have distal muscle weakness of the hands and lower leg muscles.[genecards.org]

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