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3 Possible Causes for Cerebrospinal Fluid Folic Acid Decreased

  • Kearns-Sayre Syndrome

    Cardiac conduction disease affects patients with Kearns-Sayre syndrome. We report a young asymptomatic patient with Kearns-Sayre syndrome with abnormal conduction on electrocardiogram and Holter monitor, although not advanced atrioventricular block. She underwent prophylactic pacemaker placement, and rapidly[…][]

  • Apnea Neonatorum

    The incidence has significantly decreased with maternal folic acid supplementation.[] Hydrocephalus may affect as many as 90% of newborns with myelomeningocele because the cord lesion can displace the cerebellum and interfere with cerebrospinal fluid flow.[]

  • Glutamate Formiminotransferase Deficiency

    Administration of pharmacologic doses of folic or folinic acid produced a decrease in excretion of FIGLU in urine.[] Very small amounts of FIGLU were present in the plasma of one of the patients, but FIGLU was not detectable in the cerebrospinal fluid of either patient.[]

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