Possible Causes for cerebrospinal fluid protein increased Toxoplasmosis A subclinical infection was characterized by changes in the protein levels and cell counts in cerebrospinal fluid and substantiated if T. gondii specific antibody levels remained [doi.org] […] the same or increased from birth through the first year of life. [doi.org] Peripheral Neuropathy BACKGROUND: Even though chemotherapeutic regimens show considerable importance, it may cause progressive, continuing and sometimes irreversible peripheral neuropathy. Chemotherapy induced peripheral neuropathy (CIPN) is comprised of sensory abnormalities that are most distressing issues. The mechanism associated[…] [ncbi.nlm.nih.gov] Cerebral Thrombosis Cerebrospinal fluid (CSF) shows a neutrophilic pleiocytosis of 7000/μL, total protein of 500 mg/dL, and a glucose of 0.1 mg/dL. [neurologytimes.com] Examination of the cerebrospinal fluid (CSF) does not necessarily help in establishing the diagnosis as there are no pathognomonic features. [pmj.bmj.com] Abnormalities are found in up to 84% of cases and include raised CSF pressure, increased protein content, the presence of red blood cells and pleocytosis. 5 Nevertheless, [pmj.bmj.com] Diabetes Mellitus […] intensive or very loose glycemic control may contribute to the risk of falls in diabetic patients. However, studies on diabetes mellitus and the risk of falls have yielded conflicting results. Our objective was to investigate the effect of diabetes mellitus on the risk of falls in older adults by conducting a systematic[…] [ncbi.nlm.nih.gov] Herpes Zoster Please log in to edit this article. Edit Synonym: shingles, zona German : Herpes zoster 1 Definition Herpes zoster is the secondary manifestation of an infection with Varicella zoster virus (VZV). After the primary infection with VZV, clinically presenting as " chickenpox ", the virus remains inactive in ganglia cells in[…] [flexikon.doccheck.com] Stroke The therapeutic window for intervention in acute cerebral ischemia is brief. Prehospital identification of acute stroke patients and paramedic administration of neuroprotective agents may soon become critical components of successful acute stroke treatment. This preliminary study sought to demonstrate that a new[…] [ncbi.nlm.nih.gov] Cerebral Hemorrhage On analysis, the cerebrospinal fluid was colorless and transparent, the pressure was more than 400 mm H2O, there was lymphocytic pleocytosis, increased protein, and decreased [ncbi.nlm.nih.gov] Cerebrospinal fluid (CSF) studies disclosed mononuclear pleocytosis with elevated protein levels. [ncbi.nlm.nih.gov] Both serum and CSF anti-Borrelia titers were significantly increased, and serum Western Blot showed bands to protein 34 (ops B), 57, 59 and 62. [ncbi.nlm.nih.gov] Meningitis Cerebrospinal fluid (CSF) analysis revealed pleocytosis with neutrophil predominance, increased protein and low glucose. CSF and blood cultures yielded negative results. [ncbi.nlm.nih.gov] In meningitis, CSF often shows increased protein and white blood cells and a decreased glucose (sugar) level. [baptisthealth.com] protein, and lactate in the cerebrospinal fluid and a decrease in the glucose concentration. [nejm.org] Subarachnoid Hemorrhage In the hyperacute phase of SAH, slight shortening of T1 occurs due to the increased protein and new cellular content within cerebrospinal fluid (CSF). [mriquestions.com] Paraneoplastic Syndrome Paraneoplastic Limbic Encephalitis Cerebrospinal fluid analysis reveals moderate mononuclear pleocytosis, and increased proteins, intrathecal IgG and oligoclonal bands. [pulmonologyadvisor.com] Primary Progressive Multiple Sclerosis We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…] [ncbi.nlm.nih.gov] Syphilis VDRL is the test recommended for examining cerebrospinal fluid. The use of VDRL in CSF shows a low sensitivity (30-47% false negative) and high specificity. [scielo.br] Diagnosis is made by combining the positive results of the serology test, an increase in cellularity (more than 10 lymphocytes/mL), and proteins in the CSF (over 40 mg/dL) [scielo.br] Meningioma […] metastasis, and cerebrospinal fluid dissemination. [ncbi.nlm.nih.gov] BAP1 (BRCA1-associated protein 1) is a tumor suppressor gene that is associated with multiple tumors, including rhabdoid meningiomas. [ncbi.nlm.nih.gov] Rhabdoid meningiomas are rare World Health Organization grade 3 tumors that tend to follow an aggressive course, with an increased likelihood for local recurrence, remote [ncbi.nlm.nih.gov] Myelitis Cerebrospinal fluid (CSF) examination showed a mild increase in white blood cell count (80/mm 3, 41% neutrophils) and a slightly elevated protein concentration (76 gm/dL). [ncbi.nlm.nih.gov] In some people with transverse myelitis, the cerebrospinal fluid contains more protein than usual and an increased number of white blood cells (leukocytes) that help the body [ninds.nih.gov] Lumbar puncture (also called spinal tap) uses a needle to remove a small sample of the cerebrospinal fluid that surrounds the brain and spinal cord. [ninds.nih.gov] Lyme Neuroborreliosis Cerebrospinal fluid (CSF) studies disclosed mononuclear pleocytosis with elevated protein levels. [ncbi.nlm.nih.gov] In previous studies, we showed that (I) CXCL13 levels are markedly increased in the B cell-rich cerebrospinal fluid (CSF) of patients with acute Lyme neuroborreliosis (LNB [ncbi.nlm.nih.gov] Both serum and CSF anti-Borrelia titers were significantly increased, and serum Western Blot showed bands to protein 34 (ops B), 57, 59 and 62. [ncbi.nlm.nih.gov] Lyme Meningoencephalitis The results of the test will likely show an increase in protein, globulin, and white blood cells if your dog has meningoencephalitis. [wagwalking.com] Examination of the cerebrospinal fluid obtained by a lumbar puncture procedure usually reveals increased amounts of protein and white blood cells with normal glucose, though [intranet.tdmu.edu.ua] The most important test in this case is the spinal tap, in which the veterinarian will place your dog under anesthesia and take a sample of cerebrospinal fluid to analyze. [wagwalking.com] Subdural Hematoma BACKGROUND: Delayed acute subdural hematoma (DASH) is a subdural hematoma which is detected later. An initial computed tomography (CT) does not reveal any intracranial hemorrhage at all. Few patients of DASH after mild traumatic brain injury associated with percutaneous coronary intervention (PCI) have been[…] [ncbi.nlm.nih.gov] Multiple Myeloma However, some patients may have cerebrospinal fluid (CSF) abnormalities; specifically, increased protein and decreased soluble β-amyloid or ApoE. [emedicine.medscape.com] A decreased level of consciousness, related to the size and location of the hematoma, results from compression of the contralateral hemisphere or brainstem or from increased [emedicine.medscape.com] Leptomeningeal Metastasis A case of leptomeningeal metastasis from lung adenocarcinoma is reported. In this case, we evaluated the feasibility of reverse transcriptased polymerase chain reaction (RT-PCR) methods to detect cancer cells in cerebrospinal fluids (CSF). Messenger RNA of carcinoembryonic antigen (CEA) was clearly demonstrated in[…] [ncbi.nlm.nih.gov] Systemic Lupus Erythematosus fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells. [epilepsy.com] Interferon-inducible protein 10/CXCL10 is increased in the cerebrospinal fluid of patients with central nervous system lupus. Arthritis Rheum. 2004 ; 50(11): 3731 – 2. [doi.org] […] and 26% had generalized slowing. 11 In another series of 120 patients, one-third had epileptiform activity on EEG, but no seizures were reported in the entire group. 12 In cerebrospinal [epilepsy.com] Chronic Inflammatory Demyelinating Polyneuropathy protein content in the cerebrospinal fluid in the second patient. [ncbi.nlm.nih.gov] Although cerebrospinal fluid protein levels were often increased in both groups, the elevations were generally mild or moderate in misdiagnosed patients, at an average of [news-medical.net] Doctors may use a lumbar puncture to verify the presence of increased cerebrospinal fluid protein. [en.wikipedia.org] Amyotrophic Lateral Sclerosis A normal cerebrospinal fluid (CSF) can rule out chronic radiculopathy. CSF protein and Tau can be increased in ALS, especially in particularly aggressive forms.'' [clinicaladvisor.com] Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol 2009;117(1):55-62. PubMed CrossRef Google Scholar 94. [doi.org] Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis. Ann Neurol. 1999 ;46: 129 – 31. [dx.doi.org] Subacute Transverse Myelitis If acute transverse myelitis is present, the number of certain white blood cells and the protein level in the cerebrospinal fluid is increased. [msdmanuals.com] A test of cerebrospinal fluid may show increased white cells and protein. [clevelandclinic.org] If MRI does not detect spinal cord compression, a spinal tap (lumbar puncture) is done to obtain a sample of cerebrospinal cord fluid. [msdmanuals.com] Meningeal Carcinomatosis The increase in cerebrospinal fluid proteins produces a change that is similar to that seen in subarachnoid hemorrhage on FLAIR images. [ajronline.org] Examination of cerebrospinal fluid was the most helpful diagnostic procedure; the fluid often had decreased glucose and an increased protein content and contained malignant [jamanetwork.com] We speculate that the tumor cells in meningeal carcinomatosis induce an increase in cerebrospinal fluid proteins, which is a typical laboratory finding. [ajronline.org] Multiple Sclerosis Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine [ncbi.nlm.nih.gov] Increased cerebrospinal fluid tau protein in multiple sclerosis. Eur Neurol 2000; 43(4): 228–32 PubMed CrossRef Google Scholar 107. [doi.org] Cerebrospinal fluid: rise in total protein with increase in immunoglobulin concentration with presence of oligoclonal cases. [patient.info] Guillain-Barré Syndrome fluid for increased protein level without increased cell count nerve conduction study to assess how your nerves and muscles respond to small electrical stimuli and electromyography [beaumont.org] The increase of protein level in cerebrospinal fluid is more marked in recurrent episodes. [jneuro.com] […] and legs are getting weaker loss of reflexes, which are automatic body movements you cannot control Your doctor may also order tests such as: lumbar puncture to examine cerebrospinal [beaumont.org] Cerebral Embolism Major orthopaedic procedures that involve instrumentation of the medullary canal are well known to produce showers of embolic debris including fat, bone fragments, marrow constituents, and cement. A growing literature has identified paradoxic cerebral embolism as a rare but serious consequence of the passage of[…] [ncbi.nlm.nih.gov] Viral Meningitis Significant positive correlations between the nitrite and granulocyte counts and the protein concentration in cerebrospinal fluid were found in all patients with meningitis [ncbi.nlm.nih.gov] For a definitive diagnosis of meningitis, you'll need a spinal tap to collect cerebrospinal fluid (CSF). [mayoclinic.org] Increased nitric oxide production in cerebrospinal fluid during the acute phase of bacterial meningitis may result from the inflammatory process and tissue injury. [ncbi.nlm.nih.gov] Lupus Encephalitis fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells. [epilepsy.com] Cerebrospinal fluid (CSF) evaluation revealed elevated proteins (84 mg/dL) with increased globulins, lymphocytic pleocytosis (total cells: 135/µL, White blood cells: 60 cells [ijpmonline.org] […] levels of these proteins and the soluble form of C5b-9 have been found in the cerebrospinal fluid (CSF) of SLE patients. 9 – 11 An enhanced deposition of complement activation [journals.sagepub.com] Bacterial Meningitis fluid leukocytosis, increased protein influx, and lactate accumulation. [ncbi.nlm.nih.gov] Increased neutrophil count and protein content, and decreased glucose levels in her cerebrospinal fluid initially suggested bacterial meningitis. [ncbi.nlm.nih.gov] TNF-alpha is involved in induction of a fever response and triggers the release of other cytokines, and may also influence transport of compounds into the brain, leading to cerebrospinal [ncbi.nlm.nih.gov]
