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80 Possible Causes for Cerebrospinal Fluid Protein Increased, Dyspnea, Progressive Polyneuropathy

  • Chronic Inflammatory Demyelinating Polyneuropathy

    A 44-year-old male logger complained of acute quadriplegia and dyspnea. Mechanical ventilation was initiated.[ncbi.nlm.nih.gov] Although cerebrospinal fluid protein levels were often increased in both groups, the elevations were generally mild or moderate in misdiagnosed patients, at an average of[news-medical.net] Shortly after HSCT the patient developed progressive polyneuropathy of the lower legs and hypoesthesia. Five months later a severe dementia followed.[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] Care Delivery Interventions for Dyspnea A review of supportive cancer services identified many studies, but only 6 measured dyspnea.[doi.org] However, some patients may have cerebrospinal fluid (CSF) abnormalities; specifically, increased protein and decreased soluble β-amyloid or ApoE.[emedicine.medscape.com]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome is a rare condition in pregnancy which is characterised by symmetrical progressive ascending polyneuropathy.[ncbi.nlm.nih.gov] Two patients with cerebral hemorrhagic stroke developed progressive flaccid quadriplegia and life-threatening dyspnea in acute stage.[ncbi.nlm.nih.gov] The increase of protein level in cerebrospinal fluid is more marked in recurrent episodes.[jneuro.com]

  • Amyloidosis

    Tafamidis is a TTR stabilizer that is orally administered and, by interfering with amyloid fibril formation and deposition, is capable of slowing progression of TTR polyneuropathy[ncbi.nlm.nih.gov] MGUS and myeloma patients that have atypical features, including unexplained weight loss; lower extremity edema, early satiety, and dyspnea on exertion should be considered[ncbi.nlm.nih.gov] Presentations can include fatigue, dyspnea, lack of appetite, tingling, weight loss, numbness, decreased appetite, enlarged tongue and general swelling.[symptoma.com]

  • Systemic Amyloidosis

    Hou X, Aguilar MI, Small DH (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.[doi.org] A patient who presented with dyspnea and suspected interstitial pulmonary fibrosis suffered a fatal pulmonary haemorrhage with no feasible cause for bleeding.[ncbi.nlm.nih.gov] […] information 1 Division of Cardiology, Health Insurance Hitoyoshi General Hospital, Kumamoto. k-toyama@arion.ocn.ne.jp Abstract A 73-year-old woman was admitted due to exertional dyspnea[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    Consequently, clinicians must ask about reduced exercise tolerance, dyspnea, or exercise-induced nausea. Various studies have considered the issue of screening for CVD.[clevelandclinicmeded.com] Cardiovascular Tachycardia Variable Orthostatic hypotension Skin Flushed, dry Diaphoretic, pale Respiratory Air hunger Variable Acetone odor of breath Increased respiratory rate Dyspnea[medical-dictionary.thefreedictionary.com]

  • Beriberi

    The essential feature is a polyneuropathy. b. The muscles become progressively more wasted and weak, and walking becomes increasingly difficult. c.[biologydiscussion.com] Illnesses were characterized by peripheral edema, dyspnea, palpitations, and fever.[ncbi.nlm.nih.gov] Symptoms included edema (60%), chest discomfort (54%), and dyspnea (27%). Two persons died while on board the ship (case fatality 13%).[ncbi.nlm.nih.gov]

  • Hereditary ATTR Amyloidosis

    Rapid progression of familial amyloidotic polyneuropathy: a multinational natural history study. Neurology . 2015;85(8):675-682. Hanna M.[hattramyloidosis.es] Cardiovascular involvement Patients with cardiac deposition often present with symptoms suggesting chronic heart failure (ie, dyspnea on exertion, peripheral edema, elevated[emedicine.medscape.com] Specifically, hereditary ATTR amyloidosis with polyneuropathy (hATTR-PN), also referred to as familial amyloidotic polyneuropathy (FAP) is an inherited, progressive, life-threatening[alnylam.microartswpdev.com]

  • Systemic Lupus Erythematosus

    progressive course of acute demyelinating polyneuropathy have been reported.[emedicine.medscape.com] Point-of-care ultrasound can be used to help identify the source of dyspnea in patients presenting to the emergency department.[ncbi.nlm.nih.gov] fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells.[epilepsy.com]

  • Lyme Neuroborreliosis

    ACA is occasionally associated with polyneuropathy. In stage III, chronically progressive meningoencephalitis and multifocal cerebral vasculitis can arise ( 1 ).[doi.org] The patient presented with dyspnea and pain behind the sternum, which had been occurring for several months, mainly during fast walking upstairs.[doi.org] Cerebrospinal fluid (CSF) studies disclosed mononuclear pleocytosis with elevated protein levels.[ncbi.nlm.nih.gov]

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