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11 Possible Causes for Cerebrospinal Fluid Protein Increased, Hyperintensities in the Globus Pallidus (T2-Weighted)

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  • Alexander Disease

    In addition, there are symmetrical hyperintensity signals in the posterior part of the globus pallidus on T2-weighted images in the two symptomatic patients, which are rarely[] He had megalencephaly, psychomotor retardation, seizures, and increasing elevation of increasing alpha-B crystallin and heat shock protein 27 in the cerebrospinal fluid.[] 27 in the cerebrospinal fluid.[]

  • Alpers Syndrome

    The right parietal cortex appears normal in the T2-weighted images.[] An increased protein level is seen in cerebrospinal fluid analysis.[] : A high lactic acid and pyruvic acid (acids found in the mitochondria) concentration in cerebrospinal fluid (CSF) and blood An increase in protein concentration in CSF Muscle[]

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[] Wallin A, Sjogren M: Cerebrospinal fluid cytoskeleton proteins in patients with subcortical white-matter dementia. Mech Ageing Dev 2001;122:1937–1949.[] […] in oxygen extraction fraction but maintenance of normal metabolism oligoclonal bands two to five bands of immunoglobulins on protein electrophoresis of cerebrospinal fluid[]

  • Wernicke Encephalopathy

    […] in the globus pallidus.[] Cerebrospinal fluid examination was performed in 31/36 cases, and a slightly raised protein concentration was seen in 7/31 cases.[] T1-weighted MR image depicts symmetric hyperintense foci in the globus pallidus (arrows).[]

  • Neuromyelitis Optica

    To aid in diagnosis, other MR imaging features include the following: cerebral atrophy; hyperintensities on T2-weighted images in the dentate nuclei, globus pallidus, substantia[] Cerebrospinal fluid interleukin-6 and glial fibrillary acidic protein levels are increased during initial neuromyelitis optica attacks.[] Marked increase in cerebrospinal fluid glial fibrillar acidic protein in neuromyelitis optica: an astrocytic damage marker.[]

  • Creutzfeldt Jakob Disease

    Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[] An examination of her cerebrospinal fluid revealed increased levels of 14-3-3 and total tau proteins, and abnormal conformation of the proteinase K-resistant prion protein[] No periodic activity was recorded at electroencephalography (EEG) and 14-3-3 protein was negative in the cerebrospinal fluid (CSF) sample.[]

  • Autosomal Dominant Progressive External Ophthalmoplegia Type 6

    T2-weighted axial MR image demonstrates bilateral hyperintense signal abnormalities in the globus pallidus (arrows).[] In addition, the disease may cause heart block that must be corrected with a pacemaker, increased protein in the cerebrospinal fluid, and a progressively disabling lack of[] fluid (CSF) protein and reduced folic-acid levels that are characteristic of KSS [29].[]

  • Axonal Neuropathy

    hyperintensity is also seen in the pons, middle cerebellar peduncles, and bilateral cerebellar white matter. 3 Posteromedial thalamus may also be affected. 3 The globus pallidus[] A lumbar puncture should also be done; myelin dysfunction due to an autoimmune response often causes albuminocytologic dissociation: increased cerebrospinal fluid protein[] Cerebrospinal fluid (CSF) examination (seventeen days after onset) revealed an increase in protein level (0.67 g/L, normal range: 0.15- 0.45 g/L) with the cell count within[]

  • Encephalopathy

    Conventional MRI may reveal hyperintense signal on T1-weighted images in the globus pallidus, subthalamic region, and midbrain, and may also show diffuse cortical edema and[] The main changes of cerebrospinal fluid in patients were mild to moderate increase in protein and normal or elevated cerebrospinal fluid pressure.[] hyperintensity on T2-weighted images, with sparing of the perirolandic and occipital regions.[]

  • Basal Ganglia Mass Lesion

    T2-weighted images showed small hyperintense areas in the left globus pallidus that were indistinguishable from perivascular space.[] […] in oxygen extraction fraction but maintenance of normal metabolism oligoclonal bands two to five bands of immunoglobulins on protein electrophoresis of cerebrospinal fluid[] T1-weighted image showed slightly hyperintense areas in the globi pallidi bilaterally, predominating in the left side ( Fig 1 ).[]

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