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28 Possible Causes for Cerebrospinal Fluid Protein Increased, Hyporeflexia in the Lower Limbs

  • Guillain-Barré Syndrome

    Physical examination confirmed lower left facial palsy and paresthesia of his extremities with hyporeflexia of his lower limbs and sensory loss of all four extremities.[] The increase of protein level in cerebrospinal fluid is more marked in recurrent episodes.[] One patient had grade IV/V on MRC scale weakness in upper limbs with hyporeflexia and distal paresthesias in upper limbs and hyper-reflexia in lower limbs.[]

  • Brain Abscess

    The cerebrospinal fluid shows some increase in pressure and may frequently show mild increase in protein content or leukocyte count.[] Cerebrospinal fluid is taken through the waist vertebrae ( lumbar puncture ) showed that high pressure , the amount of protein that is more than normal , but the chloride[] In the cerebrospinal fluid (CSF) after lumbar puncture with uncomplicated abscesses observed a moderate increase in the amount of protein, sometimes slight CSF pleocytosis[]

  • Poliomyelitis

    Fluid (CSF) In poliovirus infection, the CSF usually contains an increased number of white blood cells (10–200 cells/mm 3, primarily lymphocytes) and a mildly elevated protein[] Still another diagnostic test detects increased number of white blood cells and protein in the cerebrospinal fluid. This is a more general response to infections.[] Reservoir Human Transmission Fecal-oral Oral-oral possible Communicability most infectious 7-10 days before and after onset of symptoms Virus present in stool 3 to 6 weeks Cerebrospinal[]

  • Myelitis

    Loss of lower limb power was graded as severe (MRC grade 0–1), moderate (MRC grade II–III), or mild (MRC grade IV or V).[] Cerebrospinal fluid (CSF) examination showed a mild increase in white blood cell count (80/mm 3 , 41% neutrophils) and a slightly elevated protein concentration (76 gm/dL)[] In some people with transverse myelitis, the cerebrospinal fluid contains more protein than usual and an increased number of white blood cells (leukocytes) that help the body[]

  • Déjerine-Sottas Disease

    A 9-year-old boy presented progressive slight motor deficit in the lower limbs, particularly in the feet, and generalized hyporeflexia.[] CASE REPORT: A 9-year-old boy presented progressive slight motor deficit in the lower limbs, particularly in the feet, and generalized hyporeflexia.[] Neurological examination at the age of 9 years revealed slight motor deficit in the lower limbs, particularly in the feet, and generalized hyporeflexia.[]

  • West Nile Encephalitis

    […] weakness is of a lower–motor neuron pattern, with flaccid tone, areflexia, or hyporeflexia.[] fluid pleocytosis ( 5 leukocytes/mm 3 ) and elevated protein levels ( 450 mg/l); electrodiagnostic studies consistent with an anterior horn cell process; or spinal cord MRI[] […] to the headache and mental status alterations that are the usual manifesting symptoms, weakness often evolves and develops in the subacute phase of the illness. 11,12 The limb[]

  • Spinal Cord Injury

    Lower motor neurone signs in the upper limbs (atrophy, hyporeflexia).[] Scientists are studying the injection of these cells into the cerebrospinal fluid (fluid that bathes the brain and spinal cord) to promote proteins needed to grow and maintain[] Upper motor neurone signs in the lower limbs (Babinski's sign: up-going plantar reflex, hyperreflexia, clonus, spasticity).[]

  • Miller-Fisher Syndrome

    Urinary Retention Hx of rapidly progressive bilateral leg weakness e.g. after a diarrhoea illness 3-4 weeks before Examn: - Lower limb LMN signs Hyporeflexia Flaccid paralysis[] Increased cerebrospinal fluid protein content and delayed nerve conduction studies with prolonged distal latencies were encountered in both patients.[] Tendon hyporeflexia in both the upper and lower extremities were observed, and the bilateral Babinski sign was negative.[]

  • Arachnoiditis

    Clinical description Patients present with chronic, persistent deafferentiation pain in the lower back, limbs and trunk that is increased by activity, hyporeflexia, loss of[] When hydrocephalus otogenic posterior fossa predominate symptoms of increased intracranial pressure, with normal cerebrospinal fluid or "dilution" of his (poverty proteins[]

  • Myelopathy

    ), or myelopathy (spasticity and weakness in the lower limbs with or without "numb and clumsy" hands), and supported by appropriate radiological findings.[] The cerebrospinal fluid showed extremely high levels of nerve injury markers particularly glial fibrillar acidic protein (GFAP): 2 610 000/ng/L (ref. 750).[] Patients with a clinical diagnosis of cervical radiculopathy (pain along the cutaneous distribution of one or more cervical roots, sometimes associated with weakness and hyporeflexia[]

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