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15 Possible Causes for Cerebrospinal Fluid Protein Increased, Intracerebral Hematoma, Plasma Fibrinogen Increased

  • Cerebral Hemorrhage

    AIM: Hypertensive cerebral hemorrhage (HCH) is a potentially life-threatening cerebrovascular disease with high mortality.[ncbi.nlm.nih.gov] On analysis, the cerebrospinal fluid was colorless and transparent, the pressure was more than 400 mm H2O, there was lymphocytic pleocytosis, increased protein, and decreased[ncbi.nlm.nih.gov] Cerebrospinal fluid (CSF) studies disclosed mononuclear pleocytosis with elevated protein levels.[ncbi.nlm.nih.gov]

  • Cerebral Thrombosis

    When the hemorrhagic component of the infarction is large, it may look like any other intracerebral hematoma with surrounding vasogenic edema.[radiologyassistant.nl] Examination of the cerebrospinal fluid (CSF) does not necessarily help in establishing the diagnosis as there are no pathognomonic features.[pmj.bmj.com] The clinical spectrum of intracerebral hematoma, hemorrhagic infarct, non-hemorrhagic infarct, and non-lesional venous stroke in patients with cerebral sinus-venous thrombosis[ajnrdigest.org]

  • Stroke

    CT-guided stereotactic aspiration of intracerebral hematoma—result of a hematoma-lysis method using urokinase. Appl Neurophysiol. 1985 ; 48 :427–430.[doi.org] Other biological mechanisms have also been associated with physical activity, including reductions in plasma fibrinogen and platelet activity and elevations in plasma tissue[doi.org] Estimated incidence rates of first silent MRI cerebral hemorrhage ranged from 180 in the ages 30-39 to 6,900 at age 85.[ncbi.nlm.nih.gov]

  • Lupus Encephalitis

    After excluding other factors, five NPSLE patients had severe infection, two patients with status epilepticus or cerebral hemorrhage, and one patient with the liver failure[archivesofrheumatology.org] fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells.[epilepsy.com] Cerebrospinal fluid (CSF) evaluation revealed elevated proteins (84 mg/dL) with increased globulins, lymphocytic pleocytosis (total cells: 135/µL, White blood cells: 60 cells[ijpmonline.org]

  • Systemic Lupus Erythematosus

    […] clumps was present in the lung, therefor we considered the cerebral hemorrhage caused by disseminated aspergillosis.[ncbi.nlm.nih.gov] fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells.[epilepsy.com] Interferon-inducible protein 10/CXCL10 is increased in the cerebrospinal fluid of patients with central nervous system lupus. Arthritis Rheum. 2004 ; 50(11): 3731 – 2.[doi.org]

  • Thrombocytopenia

    The patient died of brain herniation complicating extensive cerebral hemorrhage.[aac.asm.org] Cerebrospinal fluid usually reveals increased protein levels and xanthochromia; less often, it is bloody.[epilepsy.com] We report the case of a patient with severe thrombocytopenia whose thromboelastometry showed clot strength that was compensated for by the increase in plasma fibrinogen levels[ncbi.nlm.nih.gov]

  • Ebola Virus Disease

    […] activation of procoagulant homeostatic mechanisms that include increases in plasma levels of TF.[jid.oxfordjournals.org] Cerebrospinal fluid analyses over time demonstrated increasing protein concentrations and cell counts, paralleled by pathologic lactate elevations in all patients.[dx.doi.org] For example, in the case of dengue HF, Wills et al. [ 35 ] postulated that dengue infection may activate fibrinolysis by degrading fibrinogen directly, thus promoting secondary[jid.oxfordjournals.org]

  • Intracranial Sinus Thrombosis

    Fortunately the patient did not develop any complication of anticoagulation therapy especially cerebral hemorrhage.[jneuro.com] , 121,122 and lower plasma fibrinogen concentration. 123,124 The deleterious risk mechanisms for those who are heavy alcohol consumers include alcohol-induced hypertension[dx.doi.org] Examination of the cerebrospinal fluid (CSF) does not necessarily help in establishing the diagnosis as there are no pathognomonic features.[pmj.bmj.com]

  • Alzheimer Disease

    Cerebral hemorrhage after passive anti-Abeta immunotherapy. Science 2002; 298(5597): 1379 PubMed CrossRef Google Scholar 31. Dodart JC, Bales KR, Gannon KS, et al.[doi.org] […] emission tomography to detect increased levels of an enzyme in cerebrospinal fluid.[britannica.com] fibrinogen levels Ramirez-Bosca et al, 2000 Depression : Mice 5,10 mg/kg, p.o Reduce the depressive like behaviour in mice, increase the levels of Serotonin and dopamine[ncbi.nlm.nih.gov]

  • Cerebral Arteriosclerosis

    Gross intracerebral hematomas. Report of 16 surgically treated cases. N. Y. St. J. Med. 1945 45 : 866 – 875 . Hamby W. B. Gross intracerebral hematomas.[thejns.org] Smoking, including passive smoking, increases platelet reactivity (possibly promoting platelet thrombosis) and plasma fibrinogen levels and hematocrit (increasing blood viscosity[merckmanuals.com] […] in oxygen extraction fraction but maintenance of normal metabolism oligoclonal bands two to five bands of immunoglobulins on protein electrophoresis of cerebrospinal fluid[strokecenter.org]

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