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84 Possible Causes for Cerebrospinal Fluid Protein Increased, Muscular Atrophy, Numbness of the Feet

  • Peripheral Neuropathy

    Muscular atrophy of hand muscles persisted. Large fibers were involved more extensively than small fibers.[ncbi.nlm.nih.gov] Numbness in the feet can lead to skin sores that do not heal. In rare cases, numbness in the feet may lead to amputation.[nlm.nih.gov] Boulis works on novel treatments for several nerve disorders, including Amyotrophic Lateral Sclerosis (ALS, also known as Lou Gehrig's disease) and Spinal Muscular Atrophy[emoryhealthcare.org]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Peroneal muscular atrophy (PMA) and related disorders. I. Clinical manifestations as related to biopsy findings, nerve conduction and electromyography.[doi.org] CIDP often causes limb weakness but may just cause problems with balance from numbness in the feet and legs.[phoenixneurology.com] protein content in the cerebrospinal fluid in the second patient.[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    RESULTS: All six patients had different degrees of muscular atrophy at nadir and in two, respiratory muscles were involved.[ncbi.nlm.nih.gov] The syndrome is "very, very variable" from person to person -- some may just experience numbness in the feet while others may suffer complete paralysis.[cbsnews.com] The increase of protein level in cerebrospinal fluid is more marked in recurrent episodes.[jneuro.com]

  • Primary Progressive Multiple Sclerosis

    In late-stage Roche, they have treatments that are being tested for Alzheimer’s disease, Autism, and for Spinal Muscular Atrophy.[mdmag.com] Numbness/tingling Another early symptom of PPMS is numbness or tingling in various body parts, such as your face, hands, and feet.[healthline.com] Roche has more than a dozen investigational medicines in clinical development for diseases that include multiple sclerosis, Alzheimer’s disease, spinal muscular atrophy, Parkinson[finance.yahoo.com]

  • Hereditary ATTR Amyloidosis

    atrophy (JASMITT study): a multicentre, randomised, double-blind, placebo-controlled trial.[researchmap.jp] Numbness or lack of feeling in the toes or feet Weakness in the legs, which can be a result of nerves irritated by the amyloid Diseases that are associated with amyloidosis[cedars-sinai.edu] It can cause loss of sensation, tingling, numbness or pain in the hands and feet (also known as peripheral neuropathy).[gethealthystayhealthy.com]

  • Syringomyelia

    It results in neurological deficits that generally consist of segmental muscular weakness and atrophy accompanied by a dissociated sensory loss (loss of pain and temperature[medical-dictionary.thefreedictionary.com] This can include, for example, tingling and a feeling of numbness in the hands or feet, or a reduced temperature - or pain in the affected areas.[avicenna-klinik.com] Symptoms • Loss of sensitivity, especially to hot and cold • Sensory loss in a "cape" distribution (over the tops of the shoulders) • Numbness and tingling in hands and feet[mayfieldchiaricenter.com]

  • Amyloidosis

    Symptoms may include any of the following: Abnormal heart rhythm Fatigue Numbness of hands or feet Shortness of breath Skin changes Swallowing problems Swelling in the arms[medlineplus.gov] Numbness or lack of feeling in the toes or feet Weakness in the legs, which can be a result of nerves irritated by the amyloid Diseases that are associated with amyloidosis[cedars-sinai.edu] Some patients may have a form of ATTR that leads to severe neuropathy with symptoms of numbness, tingling, or pain in the hands and/or feet and weakness.[saintlukeskc.org]

  • Multiple Sclerosis

    If you experience any of the following symptoms, call your doctor immediately: pain, burning, numbness, or tingling in the hands or feet; weakness in the arms or legs; or[nlm.nih.gov] Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine[ncbi.nlm.nih.gov] Increased cerebrospinal fluid tau protein in multiple sclerosis. Eur Neurol 2000; 43(4): 228–32 PubMed CrossRef Google Scholar 107.[doi.org]

  • Beriberi

    Classically it is characterized by multiple neuritis, muscular atrophy, weakness, cardiovascular changes, and progressive edema. beriberi the name given to thiamin deficiency[medical-dictionary.thefreedictionary.com] It causes tingling and numbness in the hands and feet, severe memory loss, disorientation, and confusion. What are some effects of thiamin on health?[web.archive.org] The toes feel numb and the feet have a burning sensation; the leg muscles become sore and the calf muscles cramp.[encyclopedia.com]

  • Déjerine-Sottas Disease

    He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy. Dr. H.[books.google.com] Patients can experience numbness of the feet and hands (usually noticed in the feet first) which is not often troublesome, but the tendency to have cold feet is frequent.[healthunlocked.com] […] and Pain in the Feet 399 Case 63 A Woman with Granulomatous Lesions in the Lungs and a Peripheral Neuropathy 405 Case 64 A Man with a Neuropathy Weight Loss and Lung Nodules[books.google.com]

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