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23 Possible Causes for Cerebrospinal Fluid Protein Increased, Progressive Polyneuropathy, Secondary Amyloidosis

  • Multiple Myeloma

    […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] Amyloidosis can occur as an isolated disease (primary amyloidosis) or as a result of another illness (secondary amyloidosis).[medicinenet.com] However, some patients may have cerebrospinal fluid (CSF) abnormalities; specifically, increased protein and decreased soluble β-amyloid or ApoE.[emedicine.medscape.com]

  • Amyloidosis

    Tafamidis is a TTR stabilizer that is orally administered and, by interfering with amyloid fibril formation and deposition, is capable of slowing progression of TTR polyneuropathy[ncbi.nlm.nih.gov] Secondary cutaneous nodular AA amyloidosis in a patient with primary Sjogren syndrome and celiac disease.[ncbi.nlm.nih.gov] Specifically, hereditary ATTR amyloidosis with polyneuropathy (hATTR-PN), also referred to as familial amyloidotic polyneuropathy (FAP) is an inherited, progressive, life-threatening[web.archive.org]

  • Systemic Amyloidosis

    Hou X, Aguilar MI, Small DH (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.[doi.org] The macular deposition and hemorrhage is an uncommon manifestation of secondary systemic amyloidosis secondary to familial Mediterranean fever.[ncbi.nlm.nih.gov] Patients usually present with familial amyloid polyneuropathy, with progressive peripheral and autonomic neuropathy; involvement of the heart or kidneys is variable.[doi.org]

  • Systemic Lupus Erythematosus

    progressive course of acute demyelinating polyneuropathy have been reported.[emedicine.medscape.com] fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells.[epilepsy.com] To determine the effect of diflunisal on polyneuropathy progression in patients with familial amyloid polyneuropathy.[pubpdf.com]

  • Hereditary ATTR Amyloidosis

    Rapid progression of familial amyloidotic polyneuropathy: a multinational natural history study. Neurology . 2015;85(8):675-682. Hanna M.[hattramyloidosis.es] Renal AL amyloidosis Renal amyloid Renal amyloidosis Sago spleen Secondary amyloidosis Secondary localized cutaneous amyloidosis Secondary systemic amyloidosis affecting skin[icd9data.com] Specifically, hereditary ATTR amyloidosis with polyneuropathy (hATTR-PN), also referred to as familial amyloidotic polyneuropathy (FAP) is an inherited, progressive, life-threatening[alnylam.microartswpdev.com]

  • TTR Amyloidosis with Polyneuropathy

    TTR-FAP is characterized by relentless, progressively debilitating polyneuropathy, and leads to death, on average, within 10 years of symptom onset without treatment.[ncbi.nlm.nih.gov] The authors provide instruction on all forms of amyloidosis - including primary amyloidosis (AL), secondary amyloidosis (AA), and familial amyloidosis.[books.google.com] The cerebrospinal fluid protein level was mildly increased (48 mg/dL) without the presence of any cells.[neurologyindia.com]

  • Lupus Encephalitis

    Although spinal cord is uncommonly involved, sudden onset spinal artery thrombosis, progressive demyelination and transverse myelitis have been reported.[symptoma.com] T. 1999 122 Secondary Amyloidosis has Decreased in Patients with Inflammatory Joint Disease in Finland Laiho, K. / Tiitinen, S. / Kaarela, K. / Helin, H. / Isomäki, H. 1999[tib.eu] fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells.[epilepsy.com]

  • Familial Progressive Polyneuropathy

    Abstract The purpose of this study was to evaluate the clinical and pathological features in patients with progressive-type familial amyloidotic polyneuropathy (FAP) using[ncbi.nlm.nih.gov] amyloidosi,s Inherited systemic amyloidosis, Neuropathic (Portuguese) (Swiss) amyloidosis, Secondary amyloidosis[genedx.com] Diagnostic pitfalls include inadequate attention of neurologists to autonomic symptoms, decreased nerve conduction velocity and increased protein content in the cerebrospinal[content.iospress.com]

  • Polyneuropathy

    Convert to ICD-10-CM : 356.4 converts directly to: 2015/16 ICD-10-CM G60.3 Idiopathic progressive neuropathy Approximate Synonyms Idiopathic progressive neuropathy Polyneuropathy[icd9data.com] E85.3 Secondary systemic amyloidosis E85.4 Organ-limited amyloidosis E85.8 Other amyloidosis E85.81 Light chain (AL) amyloidosis E85.82 Wild-type transthyretin-related (ATTR[icd10data.com] Cerebrospinal fluid protein was raised. Sural nerve biopsy demonstrated decreased numbers of myelinated fibres and inflammatory cell infiltrates.[ncbi.nlm.nih.gov]

  • Non-Neuropathic Heredofamilial Amyloidosis

    Transthyretin-related familial amyloid polyneuropathy (TTR-FAP) is an autosomal dominant progressive disorder characterized by a length-dependent sensorimotor polyneuropathy[ng.neurology.org] Primary amyloidosis generally affect nerves, skin, tongue, joint, heart and liver. Secondary amyloidosis usually affect spleen, kidney, liver and adrenal glands.[ivami.com] Diagnostic pitfalls include inadequate attention of neurologists to autonomic symptoms, decreased nerve conduction velocity and increased protein content in the cerebrospinal[content.iospress.com]

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