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117 Possible Causes for Cerebrospinal Fluid Protein Increased, Progressive Polyneuropathy, Weight Loss

  • Diabetes Mellitus

    In T2DM, greater degrees of weight loss lead to progressive improvements in glucose homeostasis.[doi.org] Pedersen, E, Jesudason, DR & Clifton, PM ( 2014 ) High protein weight loss diets in obese subjects with type 2 diabetes mellitus.[doi.org] Excess weight loss is defined as the actual weight loss excess weight.[clinical.diabetesjournals.org]

  • Multiple Myeloma

    […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] The horse had mild depression, weight loss, edema of the distal portion of the left hind limb, anemia, hyperproteinemia, and monoclonal gammopathy in the beta 2 region.[ncbi.nlm.nih.gov] However, some patients may have cerebrospinal fluid (CSF) abnormalities; specifically, increased protein and decreased soluble β-amyloid or ApoE.[emedicine.medscape.com]

  • Amyloidosis

    Tafamidis is a TTR stabilizer that is orally administered and, by interfering with amyloid fibril formation and deposition, is capable of slowing progression of TTR polyneuropathy[ncbi.nlm.nih.gov] MGUS and myeloma patients that have atypical features, including unexplained weight loss; lower extremity edema, early satiety, and dyspnea on exertion should be considered[ncbi.nlm.nih.gov] loss, and GI symptoms.[ncbi.nlm.nih.gov]

  • Systemic Amyloidosis

    Hou X, Aguilar MI, Small DH (2007) Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.[doi.org] Later, she developed dyspepsia and weight loss. An oesophagogastroduodenoscopy (OGD) showed Helicobacter pylori negative erosive gastritis with a benign duodenal ulcer.[ncbi.nlm.nih.gov] The most common symptoms of GI amyloidosis were diarrhea (11 patients, 45.8%), followed by anorexia (nine patients, 37.5%), weight loss, and nausea and/or vomiting (seven[ncbi.nlm.nih.gov]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Shortly after HSCT the patient developed progressive polyneuropathy of the lower legs and hypoesthesia. Five months later a severe dementia followed.[ncbi.nlm.nih.gov] We present a case of CIDP associated with ileocecal tuberculosis (TB), presenting with progressive motor weakness and significant weight loss.[ncbi.nlm.nih.gov] Although cerebrospinal fluid protein levels were often increased in both groups, the elevations were generally mild or moderate in misdiagnosed patients, at an average of[news-medical.net]

  • Hereditary ATTR Amyloidosis

    Rapid progression of familial amyloidotic polyneuropathy: a multinational natural history study. Neurology . 2015;85(8):675-682. Hanna M.[hattramyloidosis.es] loss (risk ratio, 1.81; p 0.002) were risk factors for death.[mayoclinic.pure.elsevier.com] Specifically, hereditary ATTR amyloidosis with polyneuropathy (hATTR-PN), also referred to as familial amyloidotic polyneuropathy (FAP) is an inherited, progressive, life-threatening[alnylam.microartswpdev.com]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome is a rare condition in pregnancy which is characterised by symmetrical progressive ascending polyneuropathy.[ncbi.nlm.nih.gov] Other symptoms such as dysphagia, regurgitations and weight loss were denied, and prior repeated endoscopy was otherwise unremarkable.[ncbi.nlm.nih.gov] The increase of protein level in cerebrospinal fluid is more marked in recurrent episodes.[jneuro.com]

  • Systemic Lupus Erythematosus

    progressive course of acute demyelinating polyneuropathy have been reported.[emedicine.medscape.com] loss.[ncbi.nlm.nih.gov] fluid (CSF), protein may be elevated and there may be an increase in the number of mononuclear cells.[epilepsy.com]

  • Beriberi

    The essential feature is a polyneuropathy. b. The muscles become progressively more wasted and weak, and walking becomes increasingly difficult. c.[biologydiscussion.com] Definition (MSH) A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss.[fpnotebook.com] Beriberi is a nervous system ailment caused by thiamine (vitamin B1) deficiency; its symptoms include weight loss, emotional disturbances, impaired sensory perception (Wernicke's[turtledove.fandom.com]

  • Lyme Neuroborreliosis

    ACA is occasionally associated with polyneuropathy. In stage III, chronically progressive meningoencephalitis and multifocal cerebral vasculitis can arise ( 1 ).[doi.org] As the symptoms deteriorated with ongoing weight loss, the patient was re-admitted to the hospital.[ncbi.nlm.nih.gov] Cerebrospinal fluid (CSF) studies disclosed mononuclear pleocytosis with elevated protein levels.[ncbi.nlm.nih.gov]

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