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942 Possible Causes for chemical, of, of, pain,, perception, sensory, stimulus, transduction

  • Congenital Pain Insensitivity

    Congenital pain insensitivity is a rare genetic disorder characterized by the inability to perceive pain.[symptoma.com] Pain Insensitivity [T002114] Insensitivity, Congenital Pain [T002115] Congenital Pain Indifferences [T371103] Qualifiers: blood [Q000097] ; cerebrospinal fluid [Q000134] ; chemically[slicksurface.com] Table 1 Genetics of Hereditary Sensory and Autonomic Neuropathies (HSAN) Hereditary sensory radicular neuropathy I AD 9q22.1-22.3 SPTLC1 Congenital sensory neuropathy (CSN[ojrd.biomedcentral.com] Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol. 2000 Jun;10(3):381-91. Review.[ghr.nlm.nih.gov] […] sensory and emotional experience, it substantially affects our behaviour, providing a survival advantage. 3 Normally, pain is detected by a complex system of mechanical and chemical[jmg.bmj.com] Na1.8 channels then produce most of the current necessary for the generation of action potentials and therefore transduction of pain [ 19 ].[karger.com] Indifference to pain means that the patient can perceive the stimulus, but lacks an appropriate response: they do not flinch or withdraw when exposed to pain.[en.wikipedia.org] […] neurotropic tyrosine kinase receptor type 1, which is autophosphorylated in response to nerve growth factor (NGF). 7 As previously described by Axelrod and Gold-von Simson, signal transduction[pediatrics.aappublications.org]

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  • Distal Sensory Loss (all Modalities)

    Clear Turn Off Turn On Distal sensory loss of all modalities (pain, temperature, touch, vibration) Distal sensory loss of all modalities (pain, temperature, touch, vibration[ncbi.nlm.nih.gov] All Chemicals & Bioassays Resources...[ncbi.nlm.nih.gov] The transduction of light into neural activity occurs via the photoreceptors in the retina.[courses.lumenlearning.com] Process of sensory perception.[leprosy-ila.org] Paresthesiae/dysesthesiae were the most common pain subtypes.[ahcmedia.com] Dermatomal sensory loss due to cervical radiculopathy. H . Dermatomal sensory loss due to lumbosacral radiculopathy.[neupsykey.com] Record the most distal level where the stimulus is felt. Compare the two sides.[jove.com] "Any stomach, joint pain, bone pain, muscle pain? ‎ Seite 138 - ... response).[books.google.de]

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  • Complex Regional Pain Syndrome Type II

    Complex regional pain syndrome is a condition characterized by onset of chronic pain that affects an arm or a leg.[symptoma.com] Chemicals secreted from the ends of hyperactive nerve fibers contribute to inflammation.[drjoetatta.com] […] patient with very long-standing, medically intractable and disabling, lower-limb, complex regional pain syndrome type II following the resection, crushing, and relocation of sensory[ncbi.nlm.nih.gov] In addition to SP, algogenic substances that are typically involved in tissue damage and capable of inducing transduction centripetally include potassium, serotonin, bradykinin[emedicine.medscape.com] Hyperalgesia is when a normally painful stimulus becomes much more painful than would normally occur.[omegapainclinic.com] […] the set of nerves controllinng voluntary activities) which controls a lot of bodily functions (like our heart rate, intestinal activity) as well as being important in pain perception[myvmc.com] Sensory processing also changes.[rehabwashington.com] Perception and beliefs within the medical community regarding complex regional pain syndromes changes and are still evolving.[midwestcompassion.org]

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  • Hereditary Sensory and Autonomic Neuropathy Type 1C

    Congenital insensitivity ( HSAN ) to pain is a rare disorder, which affects the body's pain-protective mechanism and predisposes the patient to increased risk and incidence[ingentaconnect.com] Nociceptors are activated in response to noxious stimuli or by the release of chemicals in response to an infectious agent/inflammation.[medicalbag.com] Available from: Introduction Hereditary sensory and autonomic neuropathy (HSAN) type 1 is an autosomal dominant disorder belonging to group of hereditary sensory and autonomic[ijdvl.com] Because of the role of Na1.7 in signal transduction to C-fibers from nociceptors (and in neurons in general) a pain signal will not be detected from the C-fibers or CNS due[hsan-iv.weebly.com] The difference threshold (Δ T ; that is, the smallest change in a stimulus that can be noticed) was calculated as the absolute value of the difference of the adaptation temperature[jneurosci.org] […] neurotropic tyrosine kinase receptor type 1, which is autophosphorylated in response to nerve growth factor (NGF). 7 As previously described by Axelrod and Gold-von Simson, signal transduction[pediatrics.aappublications.org] A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. Hum Mol Genet 2004;13:799-805. 7. Narayanan V.[contempclindent.org] Sweating could not be elicited by thermal, painful, emotional or chemical stimuli. Histamine evoked no axon flare.[jpma.org.pk]

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  • Sunburn

    […] naproxen ( Aleve ) to help relieve sunburn pain and inflammation.[medicinenet.com] KEYWORDS: Burn; Chemical burn; Frostbite; Skin injury; Sunburn; Thermal burn[ncbi.nlm.nih.gov] Abstract The ultraviolet B (UVB) sunburn model was characterized with a comprehensive battery of quantitative sensory testing (QST).[ncbi.nlm.nih.gov] Separation of oxidant-initiated and redox regulated steps in the NF-kappa B signal transduction pathway . Proc Natl Acad Sci USA 1994 ; 91 : 11527 – 11531 . 9 .[doi.org] BACKGROUND/OBJECTIVES: Understanding the public's perception of nevi and sunburn is crucial to melanoma prevention efforts.[ncbi.nlm.nih.gov] These tingles suggest an interaction with sensory neurons.[scientificamerican.com] Sunscreens function as chemicals such as oxybenzone and dioxybenzone that absorb UV radiation (chemical sunscreens) or opaque materials such as zinc oxide or titanium oxide[en.wikipedia.org] Correlates of sunburn also included older child age and higher risk perceptions.[ncbi.nlm.nih.gov]

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  • Decreased Pain Sensation

    Neuropathic pain-like alterations in muscle nociceptor function associated with vibration-induced muscle pain . Pain 2010 ; 151 : 460 – 466 . .[academic.oup.com] Sensation Thresholds for Mechanical, Thermal, and Chemical Stimulation of the Cornea T able 4.[iovs.arvojournals.org] Types of Sensory Symptoms People with MS experience three basic types of sensory symptoms, says Fred D.[everydayhealth.com] Two key lines of discovery have been ( i ) molecular/cellular transduction mechanisms and ( ii ) neuronal plasticity.[pnas.org] The perception of pain is a complex process, and mutations could potentially disrupt it at any point along the way.[thenakedscientists.com] Chemical nociceptors respond to a variety of chemicals released with tissue damage, as well as to external chemicals such as capsaicin (the chemical that makes hot peppers[webspace.ship.edu] […] the noxious stimulus.[nba.uth.tmc.edu] The left sided T3 sensory level combines with upper extremity sensory findings.[aippg.net]

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  • Neuropathy

    […] a different pain mechanism,” says Christoph Maier, a pain specialist at University Hospital Bergmannsheil in Bochum, Germany.[nature.com] […] name: eribulin) Navelbine (chemical name: vinorelbine) Taxol (chemical name: paclitaxel) Taxotere (chemical name: docetaxel) vincristine (brand names: Oncovin, Vincasar PES[breastcancer.org] Patients in whom IGT was discovered overwhelmingly had a sensory or painful sensory neuropathy.[care.diabetesjournals.org] Recent reports suggest that chemotherapy-induced neuropathy is associated with signal transduction molecules, including protein kinase C and mitogen-activated protein kinases[ncbi.nlm.nih.gov] Auditory cortical evoked potentials-through odd ball paradigm-were recorded using 64 electrodes placed on the scalp for /ba/-/da/ stimulus.[ncbi.nlm.nih.gov] (both words are interchangeable) Decreased sensation Hyperalgesia Increased perception of pain Hyperaesthesia Increased perception of stimulus (need not be pain) Hyperpathia[racgp.org.au] As a result of loss of function mutations, signal transduction at the NGF receptor is impeded and NGF dependent neurons, the small sensory and sympathetic neurons, fail to[ncbi.nlm.nih.gov] Summation (increasing pain to repeated stimulus) and after-sensation (prolonged perception of a stimulus after it is removed) are common during neuropathic pain.[practicalpainmanagement.com]

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  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    Finally, no child reported pain postoperatively.[anesthesiology.pubs.asahq.org] […] a particular segment of DNA are carried out or suppressed (gene silencing), regulating reactions involving proteins and fats (lipids), and controlling the processing of chemicals[ghr.nlm.nih.gov] Type 2, Congenital sensory neuropathy [ edit ] Hereditary sensory and autonomic neuropathy type II (HSAN2) is a condition that primarily affects the sensory nerve cells (sensory[en.wikipedia.org] Serine palmitoyltransferase catalyzes the formation of sphingolipids which are important structures in the plasma membrane enabling efficient signal transduction [ 7 , 8 ][avensonline.org] It is a distinctive sensory experience that may be described as an unpleasant awareness of a noxious stimulus or bodily damage.[indianjpain.org] Pain, superficial touch and temperature perception were diminished over distal parts of both legs while vibration and position perception was almost normal.[ijdvl.com] Nociceptors are activated in response to noxious stimuli or by the release of chemicals in response to an infectious agent/inflammation.[medicalbag.com] An mAb directed against mouse LCB1 protein (Transduction Laboratories, Lexington, Kentucky, USA) was used for the detection of human LCB1, and anti-mLCB2 Ab raised against[jci.org]

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  • Congenital Autosomal Dominant Indifference to Pain

    […] channelopathy-associated insensitivity to pain CIP congenital analgesia congenital indifference to pain congenital pain indifference indifference to pain, congenital, autosomal[ghr.nlm.nih.gov] […] sensory and emotional experience, it substantially affects our behaviour, providing a survival advantage. 3 Normally, pain is detected by a complex system of mechanical and chemical[jmg.bmj.com] Table 1 Genetics of Hereditary Sensory and Autonomic Neuropathies (HSAN) Hereditary sensory radicular neuropathy I AD 9q22.1-22.3 SPTLC1 Congenital sensory neuropathy (CSN[ojrd.biomedcentral.com] Knowledge of the molecular mechanisms of NGF-NTRK1 signal transduction promises to lead to the development of novel and effective analgesic approaches. REFERENCES 1.[journals.lww.com] It can be what we perceive as an unpleasant stimulus in our brain when we're conscious.[hstalks.com] […] but normal touch perception.[ijoonline.com] Chemical evaluation and pathological examination serve further to confirm the differences between them. Treatments for all these disorders are supportive.[ijpd.in] It is a distinctive sensory experience that may be described as an unpleasant awareness of a noxious stimulus or bodily damage.[indianjpain.org]

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  • Hypersensitive to Stimuli

    […] as pain stimuli).[jcphysiotherapy.com] The book explores mechanisms of chemical sensitivity and chronic degenerative disease, their manifestations, diagnosis, and approaches to reverse dysfunction.[books.google.de] The TCTerms Team Read more: Forum Rules of Conduct Asking a Question Asker Mother tongues: Sindhi, Urdu Hypersensitive to sensory stimuli child care Context personal development[translatorscafe.com] Women displayed elevated response curves to the arousing and unpleasant stimulus, whereas men did not.[ncbi.nlm.nih.gov] Mental attention has been shown to increase perception to gastrointestinal stimuli, 17 and there is evidence that psychological mechanisms play a role in modulating perception[gut.bmj.com] A person who struggles to deal with everyday sensory information can experience sensory overload, or information overload.[autism.org.uk] [Results] Although no group type of stimulus first stimulus interaction was observed for the extent of reaction, significant type of stimulus first stimulus interaction was[jstage.jst.go.jp] Your Migraine Brain reacts, sending chemical and pain signals throughout your brain and body.[tipsonlifeandlove.com]

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