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33 Possible Causes for Chest X-Ray Abnormal, Cotton Wool Spots

  • Multiple Myeloma

    RATIONALE: Plasma cell neoplasms are categorized by neoplastic proliferation of a single clone of plasma cells which produce a monoclonal immunoglobulin. Plasma cell neoplasms can present as a solitary plasmacytoma or as multiple myeloma. Both of them can progress to multiple myeloma. Once a diagnosis of plasmacytoma[…][ncbi.nlm.nih.gov]

  • Malignant Hypertension

    Laboratory and tests: Abnormalities on CT scan, EKG, chest X-ray, and/or urinalysis. Therapy: Parenteral (IV or IM) in the ER followed by in-patient care.[bloodpressure-drs-practical-guide.com] Cotton-wool spots, or cytoid bodies, are not exudates, but rather are retinal infarcts. Hypertensive optic neuropathy is a late finding.[ncbi.nlm.nih.gov] Decrease in visual acuity (6/7 patients) and scotoma (5/7) were the main symptoms and Elschnig spot, flamed shaped haemorrhage, serous retinal detachment, cotton wool spots[ncbi.nlm.nih.gov]

  • Non-Cranial Giant Cell Arteritis

    Additional ophthalmic manifestations include isolated cotton-wool spots, cranial-nerve palsies, ocular hypotony, and pupillary abnormalities. 2 To detect these conditions,[nejm.org] wool spots and disc abnormalities on fundoscopy murmurs of aortic regurgitation indicating ascending aortic aneurysm limb gangrene return to top Investigations lab investigations[sharinginhealth.ca] Other signs that may be associated with AAION include cotton wool spots, central retinal artery occlusion, branch retinal artery occlusion and cranial nerve involvement (especially[reviewofoptometry.com]

  • Pulmonary Arterial Hypertension

    An ECG may show some abnormalities that may be suggestive of right heart failure. Chest x-ray may also show enlargement of the chambers of the right heart.[medicinenet.com] The cotton-wool spots resolved 8 weeks after presentation and visual acuity remained stable at 20/25.[ncbi.nlm.nih.gov] Other tests available for diagnosing pulmonary hypertension include electrocardiogram ( ECG, EKG ), chest X-ray, and echocardiogram.[medicinenet.com]

  • Granulomatosis with Polyangiitis

    Chest x-rays may be abnormal, either showing diffuse disease (67%) or isolated areas (58%).[dermnetnz.org] Retinal vascular manifestations range from relatively benign cotton-wool spots, with or without associated intraretinal hemorrhages, to more severe vaso-occlusive disease,[aao.org] Also, blood tests aimed at measuring kidney function may show abnormalities. Chest x rays are used to determine if the lungs are involved.[encyclopedia.com]

  • Acute Myelocytic Leukemia

    A chest X-ray , blood tests, and other tests are done to assess your general well-being. What is the treatment for acute myeloid leukaemia?[patient.info] Characteristic signs of leukemic retinopathy include bilateral intra-retinal hemorrhage, white-centred hemorrhage, macular hemorrhage and cotton-wool spots.[ncbi.nlm.nih.gov] A chest X-ray, blood tests, and other tests are done to assess your general well-being. What is the treatment for acute myeloid leukaemia?[patient.info]

  • Plasmacytoma

    A 49-year-old woman with a history of multiple myeloma consulted to our pulmonary service with progressive dyspnoea and cough and abnormal chest X-ray.[ncbi.nlm.nih.gov] […] multiple myeloma ocular findings may include: exudative macular detachment, crystal or copper deposition in the cornea, [11] ciliary body cysts, retinal hemorrhages, and cotton-wool[eyewiki.org] spots. [4] Symptoms Patients present with proptosis, ptosis, eyelid swelling, tearing, diplopia or decreased vision.[eyewiki.org]

  • Systemic Lupus Erythematosus

    Extensive cotton wool spots were observed in the right fundus, and retinal capillary occlusions were detected by OCT angiography of the left eye.[ncbi.nlm.nih.gov] Cotton wool spots as an indicator of methotrexate-induced blood dyscrasia. Optometry. 2010;81:177–80. CrossRef PubMed Google Scholar 90. Kruh J, Foster CS.[doi.org]

  • Acquired Immunodeficiency Syndrome

    Posterior segment examination demonstrated central retinal artery occlusion in the right eye and cotton-wool spots in the left eye.[ncbi.nlm.nih.gov] On examination, he had right axillary lymphadenopathy, and cotton-wool spots were seen in the retina of the left eye.[cdc.gov]

  • Polyarteritis Nodosa

    In the posterior pole, this may manifest as hypertensive retinopathy replete with macular star formation, cotton-wool spots, and intraretinal hemorrhage in patients with renal[aao.org]

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