Childhood Cancer Causes & Reasons

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Possible Causes

Pleuropulmonary Blastoma

Read more » Families Why I Still Live in the Childhood Cancer World by Kris Doyle February 19, 2014 A parent of a childhood cancer survivor shares why she stays involved with [stbaldricks.org]

Pleuropulmonary blastoma is a very rare childhood cancer that needs to be kept in mind in the pathological differential diagnosis of thoracic tumors in the children. [ncbi.nlm.nih.gov]

OBJECTIVE: Pleuropulmonary blastoma (PPB) is a childhood cancer arising from pleuropulmonary mesenchyme. [ncbi.nlm.nih.gov]

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Gardner Syndrome

This process most often begins in childhood. If left in place, the chance that a polyp will transform into cancer by age 40 approaches 100%. [mygenecounsel.com]

[…] that they will ever develop cancer. [mygenecounsel.com]

Individuals with FAP are offered early surveillance via colonoscopies in childhood, and risk reducing surgeries if/when they develop multiple polyposis, to reduce the risk [mygenecounsel.com]

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Retinoblastoma

Great Britain 1963–2002 A MacCarthy 1, J M Birch 2, G J Draper 1, J L Hungerford 3, J E Kingston 3, M E Kroll 1, Z Onadim 4, C A Stiller 1, T J Vincent 1, M F G Murphy 1 1 Childhood [doi.org]

Abstract Retinoblastoma is one of the most common childhood cancers. The diffuse infiltrating retinoblastoma is a rare subtype of this neoplasm. [ncbi.nlm.nih.gov]

Please note that these links will take you to other sections on Cancer.Net: Cancer.Net Patient Education Videos: View short videos on childhood cancer treatment and childhood [cancer.net]

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Childhood Gastric Carcinoma

Childhood gastric cancer is a rare disease. [symptoma.com]

They account for about 3% of childhood cancers. [cancer.org]

Go Gold for Childhood Cancer- Adult Raise awareness of childhood cancer! [otrm.ritualnetwork.com]

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Nephroblastoma

INTRODUCTION: Wilms tumor (WT) or nephroblastoma is the commonest childhood cancer in Rwanda. [ncbi.nlm.nih.gov]

Economic evaluation of treatments for cancer in childhood. European Journal of cancer. 2004 Jun;40(9):1335-45. [panafrican-med-journal.com]

Childhood Cancer Survivorship Care Once treatment is complete, we offer long-term follow-up services for preventive health care, including screenings, ongoing surveillance [dukehealth.org]

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Rhabdomyosarcoma

The ACOR rhabdo-kids and the general childhood cancer list, ped-onc, are both appropriate. [web.archive.org]

Abstract We present here the results of the largest study of childhood cancer and ethnic group in Britain, based on 7,658 children treated at paediatric oncology centres throughout [doi.org]

Related Ped-onc page: Warning Signs of Childhood Cancer: Rhabdomyosarcoma Highly recommended: Rhabdomyosarcoma on the cancer.gov site R habdomyosarcoma is a fast-growing, [web.archive.org]

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Hepatoblastoma

Adelaide was a childhood cancer warrior with astounding strength and resilience — three years and 17 days was how long we were given with our precious gift. [themighty.com]

This Childhood Cancer Awareness Month, find out how our research is helping find new, better and kinder treatments for children and young people like Frankie. ... [youtube.com]

Sign in Published on Jun 24, 2019 In August 2016, Frankie was diagnosed with hepatoblastoma, a type of liver cancer. He was just two years old. [youtube.com]

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Bloom Syndrome

As a result, the best and brightest scientific discoveries for childhood cancers never actually make it into the clinic. [consano.org]

Green, Childhood Cancer in Siblings, Pediatric Hematology and Oncology, 3, 3, (229), (1986). S. Kim, T.M. Vollberg, J.-Y. Ro, M. Kim and M.A. [doi.org]

Individuals with Bloom syndrome should avoid sun exposure and undergo increased surveillance for cancer starting in childhood as cancer is the greatest cause of death in individuals [nxgenmdx.com]

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Neurofibromatosis Type 1

Hawkins, Risk of bladder tumours after childhood cancer: The British Childhood Cancer Survivor Study, BJU International, 106, 7, (1060-1069), (2010). L. [doi.org]

Childhood exams should look for signs of abnormal development. Adults require regular screening for cancer caused by the tumors. [healthline.com]

Lupo, The Role of Childhood Infections and Immunizations on Childhood Rhabdomyosarcoma: A Report From the Children's Oncology Group, Pediatric Blood & Cancer, 63, 9, (1557 [doi.org]

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Pulmonary Blastoma

Between 1975 and 2010, childhood cancer mortality decreased by more than 50%.[3] Childhood and adolescent cancer survivors require close monitoring because cancer therapy [cancer.gov]

Cancer, 62 (8), 1516-1526. (19881015)62:8 3.0.CO;2-3 Pleuropulmonary blastoma the so‐called pulmonary blastoma of childhood. / Manivel, J. [experts.umn.edu]

Louis Children’s Hospital to learn more about available treatment options for this rare type of childhood cancer. [stlouischildrens.org]

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Acute Lymphoblastic Leukemia Type L1

KEYWORDS: Acute lymphoblastic leukemia; Adult survivors of childhood cancer; Alpha diversity; Immune activation; Inflammation; Microbiome; Microbiota dysbiosis [ncbi.nlm.nih.gov]

These processes may explain the premature development of age-related chronic conditions in childhood cancer survivors. [ncbi.nlm.nih.gov]

Secondary malignancies are an important cause of morbidity and mortality in childhood cancer survivors. Salivary gland tumors account for about 6% of the second cancers. [ncbi.nlm.nih.gov]

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Denys-Drash Syndrome

Children with BWS are much more likely ( 600 times more) than other children to develop certain childhood cancers, particularly Wilms' tumor (nephroblastoma) and hepatoblastoma [mediconotebook.com]

Cancer. 2015; 112(6):1121-33. PMID: 25688735 Miller, RW, et al. Childhood cancer. Cancer. 1995; 75(1 Suppl):395-405. PMID: 8001010 Muto, R, et al. [invitae.com]

But these factors usually take many years to influence cancer risk, and they are not thought to have much of an effect on the risk of childhood cancers, including Wilms tumors [cancer.org]

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Howell-Evans Syndrome

Onset of focal keratoderma can begin in childhood and develop into esophageal cancer in middle age. • Richner-Hanhart syndrome is an autosomal recessive inheritance due to [consultant360.com]

[…] onset of focal keratoderma Oesophageal cancer in middle age White areas may be seen inside the mouth (leukokeratosis) Richner-Hanhart syndrome Autosomal recessive inheritance [dermnetnz.org]

[…] corns on the soles of the feet The variant, hereditary painful callosities, affect only the feet Howel-Evans syndrome Autosomal dominant inheritance Also called tylosis Childhood [dermnetnz.org]

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Childhood Hodgkin Lymphoma

From the underlying cohort of the British Childhood Cancer Survivor Study, a cohort of 18,123 British 5-year survivors of childhood cancer diagnosed between 1940 and 1991, [ncbi.nlm.nih.gov]

Childhood Hodgkin Lymphoma Cancer Treatment Childhood Hodgkin Lymphoma Cancer – Stages and Prognosis What is the expected life span of Childhood Hodgkin Lymphoma Cancer? [acco.org]

The disease accounts for 7% of childhood cancers and causes 1% of cancer-related deaths. [symptoma.com]

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Prostate Rhabdomyosarcoma

To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes [books.google.com]

Soft tissue sarcomas account for 7% of childhood cancers, with just over 100 children diagnosed every year in the UK. [childrenwithcancer.org.uk]

It is still a rare cancer overall, accounting for about 3% of all childhood cancers. [oncolink.org]

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Childhood Soft Tissue Sarcoma

Because cancer in children and adolescents is rare, the majority of children with cancer are treated by health professionals specializing in childhood cancers, at hospitals [stanfordchildrens.org]

Childhood soft tissue sarcomas account for approximately 10% of all childhood cancers. [cancerindex.org]

The findings confirm an association among childhood soft tissue sarcoma and cancers of the breast, bone, joint, or soft tissue as SMN in patients and in close relatives and [ncbi.nlm.nih.gov]

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Leukemia

Leukaemia is the most common cancer of childhood. [cancerindex.org]

Childhood blood cancer facts and statistics from Facts 2012. [web.archive.org]

Childhood cancers vary by type of histology, site of disease origin, race, gender, and age. [seer.cancer.gov]

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Congenital Liver Cirrhosis

ICD-10-CM Codes › P00-P96 Certain conditions originating in the perinatal period › P76-P78 Digestive system disorders of newborn › P78- Other perinatal digestive system disorders › Congenital cirrhosis (of liver) 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record P78.81 is a billable/specific ICD-10-CM[…] [icd10data.com]

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Li-Fraumeni Syndrome

Examination of the wide spectrum of adult-onset and childhood cancers and the distribution of p53 mutations has led to a greater understanding of cancer genotype-phenotype [ncbi.nlm.nih.gov]

Some authors have established criteria for a "Li-Fraumeni-like" syndrome, which comprise a patient having a childhood cancer (for example, a brain tumor, sarcoma, or adrenocortical [symptoma.com]

Clinical description The lifetime risk of cancer in LFS is about 70% for men and close to 100% for women by age 70. The risk of a childhood cancer is about 12-20%. [orpha.net]

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Congenital Hemihypertrophy

An accumulation of case reports in the past decade suggests a link between another childhood cancer, Wilms's tumor, and a rare congenital defect, total hemihypertrophy. 2 [nejm.org]

[…] in children, accounting for 6 to 8 percent of all childhood cancers. [rarediseases.org]

Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma. Proc Natl Acad Sci USA 72:5116-5120. ‎ [books.google.de]

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Brain Ependymoma

cancers. [oncologynurseadvisor.com]

“This is an exciting finding, not only for understanding the biology of a rare and particularly devastating childhood brain cancer, but also for understanding how it might [oncologynurseadvisor.com]

Johnson, PhD, principal investigator in the Center for Childhood Cancer at The Research Institute at Nationwide Children's, has received a one-year 75,000 grant from the Matthew [eurekalert.org]

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Glycogen Storage Disease Type 1

Glycogen storage disease type 1 (GSD1) is an inborn error of metabolism caused by deficiency of glucose-6-phosphatase, the enzyme catalysing the conversion of glucose-6-phosphate (G6P) to glucose. GSD1 is associated with severe hyperlipidaemia and hepatic steatosis. The underlying mechanisms responsible for these[…] [ncbi.nlm.nih.gov]

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Beckwith-Wiedemann Syndrome

[…] syndrome characterized by overgrowth (macrosomia), an increased risk of childhood cancer and congenital malformations Beckwith–Wiedemann syndrome edit Language Label Description [wikidata.org]

Children with BWS are 600 times more likely to develop certain childhood cancers. [howbigbws.com]

Children with BWS are most at risk during early childhood and should receive cancer screening during this time. [en.wikipedia.org]

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Klippel-Trenaunay-Weber Syndrome

Klippel-Trenaunay-Weber syndrome is a sporadic genetic syndrome characterized by localized hemangiomas, venous varicosities, and asymmetric osseous hypertrophy of the ipsilateral extremities. Most commonly seen in association with hemangiomas, Kasabach-Merritt syndrome is defined by the presence of[…] [ncbi.nlm.nih.gov]

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Tuberous Sclerosis

Tuberous sclerosis, otherwise referred to as Bourneville's disease or tuberous sclerosis complex, is an inherited disease that affects multiple systems. It is an uncommon condition, which leads to the formation of many tumors in various locations of the body, which are non-malignant. Tuberin and hamartin, the two[…] [symptoma.com]

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Tyrosinemia

HT1 has been transformed in the last 50 years from an aggressive often undiagnosed childhood disease causing liver failure or liver cancer, with infant death in most patients [ncbi.nlm.nih.gov]

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Cardiomyopathy due to Anthracyclines

Oeffinger KC, Mertens AC, Sklar CA, et al; Childhood Cancer Survivor Study. Chronic health conditions in adult survivors of childhood cancer. [ascopubs.org]

[…] of childhood cancer. [karger.com]

Pregnancy-associated cardiomyopathy in survivors of childhood cancer. [ncbi.nlm.nih.gov]

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Neuroblastoma

[…] solid cancer of early childhood. [newswise.com]

Outcome data were obtained for 954 5-year neuroblastoma survivors who were diagnosed in 1970-1986 and enrolled in the Childhood Cancer Survivor Study (CCSS). [ncbi.nlm.nih.gov]

Childhood Neuroblastoma Cancer Treatment Childhood Neuroblastoma Cancer – Stages and Prognosis What is the expected life span of Childhood Neuroblastoma Cancer? [acco.org]

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Medulloblastoma

Cancer Story Heroes for Hannah: Cayman Islands Community Comes Together to Cure Childhood Cancer Meet Grace [stbaldricks.org]

cancer. [ncbi.nlm.nih.gov]

[…] following: What You Need to Know About Cancer - An Overview Childhood Cancers CureSearch - National Childhood Cancer Foundation Children’s Oncology Group Late Effects of Treatment [stanfordchildrens.org]

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Osteosarcoma

Breast cancer after childhood cancer: a report from the Childhood Cancer Survivor Study. Ann Intern Med. 2004;141:590-597. PubMed Google Scholar 45. [dx.doi.org]

Childhood Cancer: Osteosarcoma Information for parents about the most common type of bone cancer. [curlie.org]

Cancer deaths due to bone and joint malignant neoplasms represent 8.9% of all childhood and adolescent cancer deaths. [dx.doi.org]

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