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15 Possible Causes for Childhood-Onset Arthralgias

  • Vasculitis

    However, renal insufficiency and end-stage renal failure have been reported and renal involvement tends to be more severe in patients with childhood onset.[orpha.net] Other systemic findings include gastrointestinal symptoms (abdominal pain, nausea, diarrhea, vomiting), musculoskeletal manifestations (arthritis and transient arthralgia[orpha.net]

  • Systemic Lupus Erythematosus

    CONCLUSION: Childhood-onset SLE encompasses a wide variety of manifestations with a female preponderance.[ncbi.nlm.nih.gov] Fever, arthralgia and pallor are the most frequent clinical manifestations among the children.[ncbi.nlm.nih.gov]

  • Cryopyrin-Associated Periodic Syndrome

    Disease onset is usually in infancy, childhood or adolescence.[symptoma.com] […] trigger. 8 The febrile attacks start in early childhood with a median age of onset of 0.8 years. 9 Between 40% and 80% of patients experience intense fatigue leading to social[dovepress.com] Additionally, conjunctivitis, arthralgia and myalgia, progressive hearing loss, visual impairment, headaches and seizures may be observed.[symptoma.com]

  • Schnitzler Syndrome

    However, renal insufficiency and end-stage renal failure have been reported and renal involvement tends to be more severe in patients with childhood onset.[orpha.net] Other systemic findings include gastrointestinal symptoms (abdominal pain, nausea, diarrhea, vomiting), musculoskeletal manifestations (arthritis and transient arthralgia[orpha.net]

  • Hemoglobin SC Disease

    The onset is usually in childhood, but real difficulties do not occur until later in life.[path.upmc.edu] Fatigue, dyspnea on effort, attacks of mild jaundice (this patient has laboratory features of hemolysis), and arthralgias are seen.[path.upmc.edu]

  • Muckle Wells Syndrome

    The onset of MWS occurs in infancy or childhood.[symptoma.com] […] trigger.8 The febrile attacks start in early childhood with a median age of onset of 0.8 years.9 Between 40% and 80% of patients experience intense fatigue leading to social[docksci.com] […] trigger. 8 The febrile attacks start in early childhood with a median age of onset of 0.8 years. 9 Between 40% and 80% of patients experience intense fatigue leading to social[dovepress.com]

  • CINCA Syndrome

    […] trigger. 8 The febrile attacks start in early childhood with a median age of onset of 0.8 years. 9 Between 40% and 80% of patients experience intense fatigue leading to social[dovepress.com] Clinical manifestations MWS is characterized by chronic or intermittent episodes of fever, headache, urticarial rash, arthralgia, or arthritis in the absence of a specific[dovepress.com]

  • Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome

    Symptom onset typically occurs in early childhood, but adult-onset cases have been reported repeatedly.[symptoma.com] Initial presentation most often occurs in childhood but age of onset can be variable and adult-onset cases have been described.[mayomedicallaboratories.com] Patients suffer from bouts of fever, skin rash, arthralgia and arthritis, myalgia, and abdominal pain. Late-onset TRAPS may also be accompanied by pleuritic chest pain.[symptoma.com]

  • Urticarial Vasculitis

    However, renal insufficiency and end-stage renal failure have been reported and renal involvement tends to be more severe in patients with childhood onset.[orpha.net] Other systemic findings include gastrointestinal symptoms (abdominal pain, nausea, diarrhea, vomiting), musculoskeletal manifestations (arthritis and transient arthralgia[orpha.net]

  • Thrombotic Thrombocytopenic Purpura

    Onset is usually acute but early symptoms may include fatigue, purpura or ecchymoses, abdominal pain, arthralgia and myalgia.[orpha.net] Clinical description Acquired TTP generally occurs in adulthood, whereas congenital TTP usually in the neonatal period or during childhood.[orpha.net]

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