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263 Possible Causes for Chills, Leukopenia, Microcytic Anemia

  • Castleman Disease

    Herein we present the case of a 49-year-old female with a 3-year history of progressively worsening lymphadenopathy associated with fevers, chills and night sweats.[] Grade- 3 AEs at least possibly attributed to siltuximab were leukopenia, lymphopenia, and a serious AE of polycythemia (n 1 each).[] Chronic, iron-refractory, microcytic anemia can be a diagnostic and therapeutic challenge.[]

  • Paroxysmal Nocturnal Hemoglobinuria

    CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([] Leukopenia, thrombocytopenia, arterial and venous thromboses, and episodic crises are common. Diagnosis requires flow cytometry.[] […] response to the action of complement, by acute episodes of hemolysis especially at night with hemoglobinuria noted upon urination after awakening, venous occlusion, and often leukopenia[]

  • Leukopenia

    One experienced chills, rigors, and dyspnea and the other experienced chills and headache. Transient leukopenia developed in both patients.[] The prognosis of leukopenia depends upon the cause, duration of leukopenia, as well as age of the patient.[] Four of the patients had a slight microcytic anemia, and their FULL TEXT[]

  • Crohn's Disease

    A 53-year-old man with Crohn's disease treated with adalimumab was hospitalised with abdominal pain, fatigue, fever and chills.[] Common adverse events included infections, mild leukopenia, abdominal symptoms, arthralgias, headache and elevated liver enzymes.[] Other signs that require a doctor's attention include fever, shaking chills, and repetitious vomiting.[]

  • Multicentric Castleman's Disease

    Since MCD is associated with a systemic inflammatory response, affected individuals typically present with fatigue, fever, chills and night sweats.[] Case report In 1994, a 19 years old girl presented with a non-erosive bilateral arthritis of hands and wrists, leukopenia and hypocomplementemia.[] Our results indicate that IL-6-induced hepcidin over-production may be involved in the pathophysiology of microcytic anemia commonly observed in this disease.[]

  • Chediak Higashi Syndrome

    Case Report A 3 year old girl child presented with complaints of high grade fever associated with chills and rigor, dry cough for seven days, decreased intake and lethargy[] Peripheral blood smear showed anisopoikilocytosis, microcytic anemia and pancytopenia. Giant granules were present in the neutrophils granulocytes and eosinophils.[]

  • Microcytic Anemia

    There was no history of fever, chills, autoimmune disorders, skin rash, joint pain or swellings, blood clots, or miscarriages.[] Around half of the patients displayed “leukopenia". • In addition to leukopenia, many patients are deficient in neutrophils (neutropenia). • Usually prolonged copper deficiency[] Iron deficiency anemia is the most common type of microcytic anemia and is also the most common anemia.[]

  • Myxedema Coma

    The patient denied any fevers, chills, nausea, abdominal pain, dysuria or diarrhea. The patient was admitted to the medicine floor for investigation of myoclonic jerks.[] DTR’s -Stigmata of hypothyroidism: Myxedema, swollen lips, periorbital edema, puffy hands/face, thickened nose Labs: – Hyponatremia (in 50% of patients , can be severe) – Leukopenia[] anemia secondary to hemorrhage, or macrocytic anemia caused by vitamin B12 deficiency, or normocytic normochromic anemia, which may be secondary to decreased oxygen requirement[]

  • Myelofibrosis

    Tell your healthcare provider if you develop any of the following symptoms of infection: chills, nausea, vomiting, aches, weakness, fever, painful skin rash or blisters.[] Thrombocytopenia, defined as platelet count 100 109/L (moderate 51-100 109/L; severe 50 109/L), was associated with anemia (76% vs. 45%, p 0.001), leukopenia (29% vs. 11%,[] anemia or erythrocytosis, elliptocytosis, Howell-Jolly bodies, target cells, teardrop cells; leukocytosis–15-40 x 1012/L with 'bands', ie left shift of granulocytes, juvenile[]

  • Pernicious Anemia

    A doctor should be seen if fever, chills, muscle aches, or new symptoms develop during treatment, or if symptoms do not improve after two weeks of treatment.[] A deficiency of white blood cells ( leukopenia ) and platelets ( thrombocytopenia ) in the blood may occur.[] Diagnostic dilemmas could occur when patients with PA present with spuriously normal or high cobalamin levels, normocytic or microcytic anemia, non-anemic macrocytosis, autoimmune[]

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