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14 Possible Causes for Chloride Decreased, Hyponatremia, Major Cause of Death is Heart Failure

  • Congestive Heart Failure

    Increases in renin, mediated by a decreased stretch of the glomerular afferent arteriole, reduce delivery of chloride to the macula densa and increase beta1-adrenergic activity[emedicine.com] We describe the use of conivaptan in a 4-month-old infant girl with severe hypervolemic hyponatremia and heart failure.[ncbi.nlm.nih.gov] Major secondary outcomes were all cause mortality during the trial period, all reported cardiovascular deaths, admission to hospital for heart failure, cardiovascular admission[doi.org]

  • Chronic Kidney Insufficiency

    Hypocalcemia (see chapter) Hyponatremia (see chapter) Uremia: The three most severe forms of uremia are encephalopathy, bleeding diathesis, and pericarditis.[clinicaladvisor.com] Early detection can help prevent the progression of kidney disease to kidney failure. Heart disease is the major cause of death for all people with CKD.[kidney.org] […] complications, but the common one are listed below: Acidemia Hyperkalemia Volume/fluid overload Hypocalcemia/hyperphosphatemia (as a consequence of secondary hyperparathyroidism) Hyponatremia[clinicaladvisor.com]

  • Chronic Right-Sided Congestive Heart Failure

    Specifically, tolvaptan is approved by the FDA for the treatment of euvolemic hyponatremia and hypervolemic hyponatremia.[healio.com] History of Congestive Heart Failure Congestive heart failure is, in a nutshell, the end stage for all chronic disease affecting the heart, and as such is a major cause of[ceufast.com] Monitor for hyponatremia. For pulmonary edema, an extreme of CHF, morphine and IV nitrates are adjuncts.[epmonthly.com]

  • Kidney Failure

    Common electrolytes that are measured by doctors with blood testing include sodium, potassium, chloride, and bicarbonate.[medicinenet.com] Patients with hypervolemic hyponatremia and kidney failure pose a special therapeutic challenge.[ncbi.nlm.nih.gov] Early detection can help prevent the progression of kidney disease to kidney failure. Heart disease is the major cause of death for all people with CKD.[kidney.org]

  • Hypervolemia

    Thiazide diuretics, in particular, decrease the kidneys’ diluting capacity and increase sodium excretion.[merck.com] Patients were classified as having a major CV event if the main cause of death or hospitalization was acute coronary syndrome, ischemic heart disease, congestive heart failure[revportcardiol.org] We sought to identify factors that predispose patients to hyponatremia and to find predictive factors associated with increased risk of water intoxication.[ncbi.nlm.nih.gov]

  • Heart Failure

    Increases in renin, mediated by a decreased stretch of the glomerular afferent arteriole, reduce delivery of chloride to the macula densa and increase beta1-adrenergic activity[emedicine.com] hyponatremia and edema.[uscjournal.com] Major secondary outcomes were all cause mortality during the trial period, all reported cardiovascular deaths, admission to hospital for heart failure, cardiovascular admission[doi.org]

  • Hypertension

    […] glomerulonephritis at high doses. 207–209 Pyridoxamine and OPB-9195 remain in preclinical testing; the latter reduces blood pressure in genetically hypertensive rats and decreases[doi.org] Drugs to treat hypertension have well-known adverse effects, including hypokalemia, hyperkalemia, hyponatremia, hypotension, dizziness, headache, edema, erectile dysfunction[doi.org] High blood pressure is a major contributing risk factor to heart failure, heart attack, stroke, and chronic kidney disease.[doi.org]

  • Renal Impairment

    Activation of the tubuloglomerular feedback mechanism and the resultant decrease in GFR during acute renal ischemia would decrease sodium chloride delivery to damaged tubules[jci.org] Electrolyte changes such as hypernatremia and hyperkalemia were more common in group A than group B, whereas hyponatremia, hypokalemia, and hypophosphatemia were more common[ncbi.nlm.nih.gov] Early detection can help prevent the progression of kidney disease to kidney failure. Heart disease is the major cause of death for all people with CKD.[kidney.org]

  • Myocardial Infarction

    This decreases tubular reabsorption of sodium and chloride, and increases urinary excretion of sodium and water .[doi.org] […] oral carbohydrate-electrolyte (CE) liquids (I), compared with drinking water (C), change volume/hydration status, vital signs, development of hyperthermia, development of hyponatremia[doi.org] ., MD Scope and Significance C oronary artery disease is a major cause of morbidity and mortality as a result of acute myocardial infarction (MI) or subsequent heart failure[ncbi.nlm.nih.gov]

  • Low Cardiac Output Syndrome

    Decreased afferent glomerular arteriolar blood flow, increased renal sympathetic nerve discharge and a resultant decreased sodium chloride delivery around macula densa stimulates[ncbi.nlm.nih.gov] Specifically, tolvaptan is approved by the FDA for the treatment of euvolemic hyponatremia and hypervolemic hyponatremia.[healio.com] LCOS can be considered a form of acute heart failure (AHF).[revespcardiol.org]

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