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12 Possible Causes for Cholestatic Jaundice, Hyperbilirubinemia, Onset in First Weeks or Months of Life

  • Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] The outcomes of patients with cholestatic jaundice depend on the cause.[ncbi.nlm.nih.gov] We believe our patient’s persistent direct hyperbilirubinemia with biopsy-confirmed cholestasis was also likely related to his AHC.[pediatrics.aappublications.org]

  • Intrahepatic Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] Intrahepatic cholestatic jaundice of pregnancy presents as pruritus, abnormal liver biochemistry and increased serum bile acids.[ncbi.nlm.nih.gov] In this case series, all patients manifested prolonged cholestatic jaundice and elevated citrulline levels.[ncbi.nlm.nih.gov]

  • 3Beta-Hydroxy-Delta5-C27-Steroid Oxidoreductase Deficiency

    The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[findzebra.com] Clinically, the initial symptom is cholestatic jaundice, caused by the blockage of bilirubin flow.[symptoma.com] jaundice and malabsorption of lipids and lipid-soluble vitamins from the gastrointestinal tract.[ncbi.nlm.nih.gov]

  • Benign Recurrent Intrahepatic Cholestasis

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] We report the case of a young male patient with benign recurrent intrahepatic cholestasis who presented to us with recurrent cholestatic jaundice and pruritus with negative[ncbi.nlm.nih.gov] HYPERBILIRUBINEMIA 2.[slideshare.net]

  • Benign Recurrent Intrahepatic Cholestasis Type 1

    Clinical description The first cholestatic episode can occur at any age but onset within the first two decades of life is most common.[orpha.net] There is initial elevation of serum bile acids, followed by cholestatic jaundice which generally spontaneously resolves after periods of weeks to months.[genecards.org] HYPERBILIRUBINEMIA 2.[slideshare.net]

  • Hemorrhagic Disease of the Newborn

    It usually occurs from the second day of life to the end of the first week; however, it can occur during first month and sometimes overlaps with late-onset vitamin K deficiency[emedicine.com] jaundice. 1, 2, 3, 4 However, recent studies report low levels of vitamin K even 2 to 3 weeks after birth in newborns exclusively breastfed who received im prophylaxis at[nature.com] […] gestational age infant (LGA) Physical maturity Pathology of prematurity Gross appearance of premature infant Difficulties in maintaining homeostasis Thermoregulation Hypoglycemia Hyperbilirubinemia[atlases.muni.cz]

  • Sepsis

    Early-onset sepsis is seen in the first week of life. Late onset sepsis occurs after 1 week through 3 months of age.[medlineplus.gov] […] anemia, thrombocytopenia, cholestatic jaundice, and hepatosplenomegaly in malaria-endemic zones.[ncbi.nlm.nih.gov] Hyperbilirubinemia did not return in 3 months.[ncbi.nlm.nih.gov]

  • Streptococcal Septicemia

    […] are infected within the first week of life, it is called early-onset GBS disease.[sepsis.org] Liver function tests Serum bilirubin and alkaline phosphatase levels can become elevated and cholestatic jaundice may develop later in the disease process as liver function[atsu.edu] […] homocystinaemia (Br Eng) hydremia (Am Eng) or hydraemia (Br Eng) hydroxyprolinemia (Am Eng) or hydroxyporlinaemia (Br Eng) hyperamylasemia (Am Eng) or hyperamylasaemia (Br Eng) hyperbilirubinemia[wordlister.blogspot.com]

  • Hepatoerythropoietic Porphyria

    […] of seizures in the first weeks or months of life.[mendelian.co] At the age of 38 years, cholestatic jaundice and rapidly deteriorating liver function developed. The patient died of massive bleeding from esophageal varices.[jamanetwork.com] , red urine, dark diapers that show a red fluorescence under UV light Phototherapy for hyperbilirubinemia leads to severe skin blistering.[merckmanuals.com]

  • Pneumatosis Vaginalis

    […] two years of life, peak incidence at 6 weeks of age Seasonal pattern - winter and early spring months Clinical Picture Symptoms • Sudden onset of respiratory difficulty •[flashcardmachine.com] jaundice (2).[hawaii.edu] Hypertrophic Cardiomyopathy, Hyperbilirubinemia, & Polycythemia 6.[cram.com]

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