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17 Possible Causes for Chronic Active Hepatitis, Petechiae, Virus Associated Hemophagocytic Syndrome

  • Infectious Mononucleosis

    Treatment of patients with infectious mononucleosis need not include prolonged bed rest and restriction of activity in an effort to avoid the development of chronic liver[] Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[]

  • Chronic Active Hepatitis B

    Abstract Reports on the histologic findings of chronic active hepatitis C (CAH-C) have been rare, and the characteristic histologic findings of CAH-C have been not yet determined[] Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[] These patients experience urticaria, rash, petechiae, palpable, purpura, arthralgia and arthritis of small joints.[]

  • Familial Hemophagocytic Lymphohistiocytosis

    Fatal virus-associated hemophagocytic syndrome associated with coexistent chronic active hepatitis B and acute hepatitis C virus infection.[] It is concluded that a viral infection cannot serve as the sole criterion for distinguishing a virus-associated hemophagocytic syndrome as an entity separate from familial[] Patient B:2 was similarly thrombocytopenic, had a prolonged coagulation profile, and developed petechiae.[]

  • Hypersplenism

    Four patients had portal vein obstruction and three had hepatic cirrosis, two patients had chronic active hepatitis with hypersplenism.[] Case Report. ( 27227931 ) Lu X.X....Zheng S. 2016 21 Severe hypersplenism associated to hemophagocytic and lymphoproliferative syndrome secondary to Epstein-Barr virus infection[] Figure 67-8 Petechiae and ecchymoses in a patient with idiopathic thrombocytopenic purpura. (Courtesy of Sidney Sussman, MD.)[]

  • Hepatosplenomegaly

    […] anaemia sickle cell anaemia thalassaemia chronic liver disease and portal hypertension: chronic active hepatitis amyloidosis acromegaly systemic lupus erythematosus Links:[] T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol. 1991; 97 :189–194. [ PubMed ] 16.[] CLINICAL EXAMINATION General examinationPallor - Already discussedPetechiae, purpura, ecchymosis, lymphadenopathy etc. - LeukaemiaJaundice - Liver disease / haemolytic[]

  • Infectious Mononucleosis Hepatitis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[] Tonsillar enlargement, pharyngeal erythema, palatal petechiae, lymphadenopathy, and jaundice were noted.[] Active Hepatitis 248 Role of the Liver Biopsy in Differential Diagnosis 255 Chronic Persistent Hepatitis and Chronic Lobular Hepatitis 259 References 265 Associated Autoimmune[]

  • Chronic Ebstein-Barr Virus Infection

    […] infection. ( 28381684 ) Onozawa E....Arai A. 2017 11 Chronic active Epstein-Barr virus infection associated with hemophagocytic syndrome and extra-nodal natural killer/T-cell[] Red dots (petechiae) may be seen on the palate. Up to half of infected people will have an enlarged spleen, and 10% will have an enlarged liver on abdominal examination.[] However, severe chronic active EBV infection with hepatic involvement in adults is quite rare.[]

  • Hydroa Vacciniforme-Like Lymphoma

    Chronic Active EBV Infection of T- and NK- Cell Type, Systemic Form CAEBV of systemic form is characterized by persistent clinical symptoms and signs including fever, hepatosplenomegaly[] In contrast out of 11 severe patients in this study, 6 had evidence of chronic EBV infection, 5 had hypersensitivity to mosquito bites, 4 had virus-associated hemophagocytic[] The wide variety of secondary manifestations of leukemia includes petechiae and ecchymoses and pyoderma gangrenosum.[]

  • Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[] In the late stages, ecchymoses and petechiae may result from thrombocytopenia.[] Known hepatitis C virus (HCV) positive with chronic HCV or active viral infection with HCV hepatitis requiring anti-viral medication (at time of randomization).[]

  • Hepatosplenic Lymphoma

    Primary hepatic malignant lymphoma:its occurrence in a patient with chronic active hepatitis, cirrhosis, and hepatocellular carcinoma associated with hepatitis B viral infection[] In 1 patient, a low level of fibrinogen associated with increased triglyceridemia and ferritinemia suggested hemophagocytic syndrome, which was confirmed by bone marrow examination[] Petechiae and suffusions were present on the skin of the thoracic region and flanks.[]

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