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132 Possible Causes for Chronic Denervation, Muscle Twitch

  • Spinal and Bulbar Muscular Atrophy

    It is suggested that, in the process of chronic denervation and reinnervation of X-SBMA, reinnervated motor endplates may be associated with the defect of neuromuscular transmission[ncbi.nlm.nih.gov] Early symptoms include tremor of the outstretched hands, muscle cramps with exertion, and fasciculations (fleeting muscle twitches visible under the skin).[ninds.nih.gov] Electromyography showed chronic denervation potentials in his cranial, cervical, thoracic, and lumbosacral myotomes without myotonic discharge.[ncbi.nlm.nih.gov]

  • Peripheral Neuropathy

    Survival of Schwann cells in chronically denervated skeletal muscles. Acta Neuropathol. 2002; 103 :565–574. [ PubMed ] [ Google Scholar ] 72.[ncbi.nlm.nih.gov] On clinical examination, muscle twitches of fingers of both hands, as well as the abductor halluces and the dorsal interossei muscles of the right foot were observed.[ncbi.nlm.nih.gov] Survival of Schwann cells in chronically denervated skeletal muscles. Acta Neuropathol . 2002; 103 :565-574. [ PubMed ] [ DOI ] 72.[doi.org]

  • Motor Neuron Disease

    Electromyography revealed generalized active and chronic denervation and fasciculations. A genetic test showed 46 CAG repeats in the huntingtin gene.[ncbi.nlm.nih.gov] A 69-year-old man with long-standing depression and failing memory presented with muscle twitches of 8 months' duration.[ncbi.nlm.nih.gov] Myography revealed chronic denervation signs. The patient had serum anti-Ri onconeural antibodies. The diagnosis of paraneoplastic MND was established.[ncbi.nlm.nih.gov]

  • Multifocal Motor Neuropathy

    In this case of MMN without conduction blocks we found multifocal nerve enlargements in the ultrasonography and electrodiagnostic signs of acute and chronic denervation associated[ncbi.nlm.nih.gov] Usually beginning in one or both hands, MMN is characterized by weakness, muscle atrophy, cramping, and often profuse fasciculations (muscle twitching).[en.wikipedia.org] The most important of these findings are the reinnervation motor unit action potentials seen together with chronic denervated motor unit action potentials and this makes an[marmaramedicaljournal.org]

  • Muscle Spasm

    Identifying patients with chronic low back pain likely to benefit from lumbar facet radiofrequency denervation: a prospective study.[epainassist.com] Rare causes of Muscle Twitching and Spasms Following causes of Muscle Twitching and Spasm which makes it necessary to meet your doctor ASAP – Muscle twitching in neck, hips[myfitfuel.in] The Difference between Muscle Spasms and Twitching The main difference between a spasm and a twitch is movement.[nativeremedies.com]

  • Upper Motor Neuron Disease

    Electrophysiology has also revealed that LMNs may show transient or chronic denervation in PLS patients, further eroding the concept of PLS as separate from ALS.[wiki.iop.kcl.ac.uk] Lower motor neuron disease causes weakness, loss of muscle ("atrophy") and muscle twitching ("fasciculations").[neurology.emory.edu] […] wasting and weakness, absent reflexes, loss of weight and muscle twitching.[mndnsw.asn.au]

  • Paraneoplastic Syndrome

    Despite multiple immunomodulatory therapies, the patient progressed and demonstrated electrodiagnostic evidence for a chronic axonal polyradiculoneuropathy with ongoing denervation[doi.org] Accordingly, this syndrome is associated with muscle weakness, muscle wasting, and muscle twitching.[brighamandwomens.org] […] to muscle twitching and cardiac arrhythmias.[merckmanuals.com]

  • Progressive Muscular Atrophy

    Electrodiagnostic testing showed chronic denervation, most prominent in the face, tongue, and proximal muscles.[neuromuscular.wustl.edu] This then leads to fasciculations (muscle twitches), progressively worsening muscle weakness, and a loss of muscle mass and weight.[mndcentre.org.uk] Symptoms The symptoms of progressive muscular atrophy include the following: Weakness in the hands that spreads into the lower body Muscle wasting Twitching and muscle cramps[healthcare.utah.edu]

  • Amyotrophic Lateral Sclerosis

    The most important test for confirming the diagnosis of ALS is electromyography to show acute and chronic denervation as a sign of lower motor neuron involvement.[clinicaladvisor.com] twitching for 3 years.[ncbi.nlm.nih.gov] 4) and signs of acute and/or chronic denervation on EMG; and (iv) Stage 4, moderate or severe weakness (Medical Research Council 3 and below) and marked acute and chronic[doi.org]

  • Lyme Disease

    The initial electrodiagnostic test showed widespread active and chronic denervation findings.[ncbi.nlm.nih.gov] Harris adds that, "Symptoms can range from sore muscles, sore back, sore neck, anxiety, fatigue, heart palpitations, muscle twitches, bladder pain, vision or hearing problems[eonline.com] Other clues to Lyme disease have been identified, although these have not been consistently present in each patient: numbness and tingling, muscle twitching, photosensitivity[web.archive.org]

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