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160 Possible Causes for Chronic Fatigue Syndrome, Cryoglobulinemia, Hepatomegaly

  • Chronic Hepatitis C

    Inflammation leads to the enlargement of the liver (hepatomegaly) in over 60% of people infected with hepatitis C and can cause the fibroelastic sheath (Glisson’s capsule)[hepctrust.org.uk] fatigue syndrome · and hemophagocytic syndrome.[books.google.com] Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis B

    Clinical signs include liver tenderness, hepatomegaly, and splenomegaly. Acute HBV infection typically lasts two to four months.[aafp.org] Long-term complications Liver cirrhosis Hepatocellular carcinoma ( HCC ) Post‑hepatitis syndrome Chronic fatigue, weakness Nausea, loss of appetite Possible upper quadrant[amboss.com] Other rare extrahepatic manifestations are mixed essential cryoglobulinemia, pericarditis, and pancreatitis.[clevelandclinicmeded.com]

  • Infectious Mononucleosis

    The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus[ncbi.nlm.nih.gov] fatigue syndrome (CFS), and the risks of exercise at various points in the disease process.[ncbi.nlm.nih.gov] Arima, Mami Tamai, Satoshi Yamasaki, Hideki Nakamura, Hiroyuki Moriuchi and Atsushi Kawakami, An elderly patient with chronic active Epstein–Barr virus infection with mixed cryoglobulinemia[oadoi.org]

  • Chronic Lymphocytic Leukemia

    0 lymphocytosis in the blood and marrow only (survival 120 months) Stage I lymphocytosis and adenopathy (survival 95 months) Stage II lymphocytosis, splenomegaly and/or hepatomegaly[flexikon.doccheck.com] We describe herein a case of an unusually severe articular syndrome with the use of ibrutinib in a patient with 17 p minus chronic lymphocytic leukemia.[ncbi.nlm.nih.gov] Callard, Magali Colombat, Jean Cabane, Jean-Jacques Boffa, Pierre Aucouturier and Pierre Ronco, Membranoproliferative Glomerulonephritis, Chronic Lymphocytic Leukemia, and Cryoglobulinemia[doi.org]

  • Viral Hepatitis

    Three patients presented only jaundice and hepatomegaly; one also had liver failure.[ncbi.nlm.nih.gov] A number of conditions, such as chronic arthritis, demyelinating diseases such as multiple sclerosis, sudden infant death syndrome, autism, chronic fatigue syndrome, leukemia[clinicaladvisor.com] HCV RNA can be demonstrated in the tumor as well as in surrounding liver tissue although HCV RNA cannot be integrated in the hepatocytic DNA. 3--Essential cryoglobulinemia[meddean.luc.edu]

  • Systemic Lupus Erythematosus

    Other signs are: Pancreatitis, Lupus Enteropathy, Hepatitis and Hepatomegaly 5. Systemic Fever, Malaise/Fatigue, Lymphadenopathy, Weight loss 6.[fidanoski.ca] It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[mollysfund.org] Sakr, Association of BAFF 871C/T Promoter Polymorphism with Hepatitis C-Related Mixed Cryoglobulinemia in a Cohort of Egyptian Patients, Molecular Diagnosis & Therapy, 10.1007[doi.org]

  • Multiple Myeloma

    In rare cases, individuals with multiple myeloma may have an abnormally large liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] Type I multiple myeloma-associated cryoglobulinemia was diagnosed.[ncbi.nlm.nih.gov] […] autonomic neuropathy in nondiabetic patients, “left ventricular hypertrophy” on echocardiography without consistent electrocardiographic evidence or low limb lead voltages, hepatomegaly[bloodjournal.org]

  • Hepatitis B

    fatigue syndrome · and hemophagocytic syndrome.[books.google.com] RESULTS: Clinical history, examinations, and laboratory results suggest HBV-associated cryoglobulinemia and vasculitis.[ncbi.nlm.nih.gov] Other disorders--essential mixed cryoglobulinemia and polymyalgia rheumatica--have also been linked to HBV, but these associations are more controversial.[ncbi.nlm.nih.gov]

  • Liver Disease

    CASE REPORT In 1979, CESD was first diagnosed in a 13-year-old female with marked hepatomegaly.[ncbi.nlm.nih.gov] Keratoconjunctivitis (sicca syndrome), glomerulonephritis, skin disorders (for example, lichen planus, porphyria cutanea tarda), neuropathy, and immune dysfunction (for example, cryoglobulinemia[ssa.gov] Clonal analysis of intrahepatic B cells from HCV-infected patients with and without mixed cryoglobulinemia. J Immunol. 1998; 160: 3594-601 40.[doi.org]

  • Acquired Immunodeficiency Syndrome

    Hepatomegaly and/or splenomegaly was noted among 26% of patients.[web.archive.org]

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