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173 Possible Causes for Chronic Fatigue Syndrome, Cryoglobulinemia, Raynaud's Disease

  • Sjögren Syndrome

    Two overlapping conditions known to many with lupus are Sjogren’s syndrome and Raynaud’s disease, also known as Raynaud’s phenomenon.[resources.lupus.org] Komaroff, The Frequency of HLA Class II Antigens in Chronic Fatigue Syndrome, Journal of Chronic Fatigue Syndrome, 11, 4, (33), (2003). Juan-Manuel Anaya, Paula A.[doi.org] Serum cryoglobulinemia was measured in all patients.[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    The most common symptoms are joint pain (arthralgia), pain and numbness in the fingers and toes in response to cold (Raynaud’s phenomenon), weakness, and purpura.[rarediseases.org] Type I multiple myeloma-associated cryoglobulinemia was diagnosed.[ncbi.nlm.nih.gov] The monoclonal immunoglobulin binds to erythrocyte carbohydrate antigens resulting in hemolytic anemia, Raynaud phenomenon, and acrocyanosis after cold exposure. 80 Warm antibody[doi.org]

  • Chronic Active Hepatitis B

    Long-term complications Liver cirrhosis Hepatocellular carcinoma ( HCC ) Post‑hepatitis syndrome Chronic fatigue, weakness Nausea, loss of appetite Possible upper quadrant[amboss.com] Other rare extrahepatic manifestations are mixed essential cryoglobulinemia, pericarditis, and pancreatitis.[clevelandclinicmeded.com] HEMOPOIETIC SYSTEM : aplastic anemia (rare).Cryoglobulinemia of mixed type can be seen in hepatitis B infection.[meddean.luc.edu]

  • Rheumatoid Arthritis

    […] of Bone Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome (PFAPA) (Pediatrics) Polymyalgia Rheumatica Psoriatic Arthritis (PsA) R Raynaud's Phenomenon Reactive[rheumatology.org] An intriguing and hitherto unexplained co-occurrence: Depression and chronic fatigue syndrome are manifestations of shared inflammatory, oxidative and nitrosative (IO&NS)[ncbi.nlm.nih.gov] Preliminary studies have shown that Rituximab was also found to be beneficial in treating severe rheumatoid arthritis complicated by blood vessel inflammation (vasculitis) and cryoglobulinemia[medicinenet.com]

  • Raynaud Phenomenon

    Treatment for Raynaud's disease There is no cure for Raynaud’s disease or Raynaud’s phenomenon.[ucdmc.ucdavis.edu] fatigue syndrome Reflex sympathetic dystrophy Carpal tunnel syndrome Magnesium deficiency Multiple sclerosis Erythromelalgia (clinically presenting as the opposite of Raynaud's[en.wikipedia.org] Other causes of blue digits include cryoglobulinemia, hyperviscosity states, and APL syndrome.[rheumaknowledgy.com]

  • Systemic Lupus Erythematosus

    Some patients with SLE have Raynaud's phenomenon.[web.archive.org] It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[kaleidoscopefightinglupus.org] Sakr, Association of BAFF 871C/T Promoter Polymorphism with Hepatitis C-Related Mixed Cryoglobulinemia in a Cohort of Egyptian Patients, Molecular Diagnosis & Therapy, 10.1007[doi.org]

  • Raynaud's Disease

    The primary Raynaud’s phenomenon is also known as the Raynaud’s disease.[symptoma.com] fatigue syndrome Reflex sympathetic dystrophy Carpal tunnel syndrome Magnesium deficiency Multiple sclerosis Erythromelalgia (clinically presenting as the opposite of Raynaud's[en.wikipedia.org] Hepatitis B surface markers were found in 10 of these patients with cryoglobulinemia.[ncbi.nlm.nih.gov]

  • Chronic Hepatitis C

    Abnormal blood flow resulting from cryoglobulinemia may lead to Raynaud phenomenon, in which small blood vessels in the fingers and toes spasm in response to cold temperatures[britannica.com] fatigue syndrome · and hemophagocytic syndrome.[books.google.com] Approximately 80% of patients with hepatitis C virus infection develop chronic liver disease as cirrhosis, and 40% develop autoimmune complications as mixed cryoglobulinemia[ncbi.nlm.nih.gov]

  • Vasculitis

    Some of the most common types of vasculitis are: Raynaud’s disease (Raynaud's phenomenon) Buerger’s disease (thromboangitis obliterans) Takayasu’s arteritis The UC Davis Vascular[health.ucdavis.edu] Common symptoms of the disease include chronic fatigue, weakness, fever, abdominal pain, renal insufficiency, neurological dysfunction, hypertension, asymmetric polyneuropathy[disabilitybenefitscenter.org] It represents 70–80% of cryoglobulinemia renal diseases and it is strongly associated with the type II IgM κ mixed cryoglobulinemia.[journals.lww.com]

  • Livedo Reticularis

    It may be associated with autoimmune diseases, vasculitis, Raynaud’s phenomenon, fibromyalgia, atheromatous disease, hyperviscosity syndrome, thrombotic conditions, and exposure[rheumaknowledgy.com] Fibromyalgia This chronic condition may produce mottled skin as a mild symptom compared to the traditional severe muscle pain, insomnia, and general fatigue. 6.[doctorshealthpress.com] Classically, monoclonal cryoglobulinemia is associated with hematologic malignancies, whereas mixed cryoglobulinemias are reported in association with hepatitis C virus infections[ncbi.nlm.nih.gov]

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