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2,081 Possible Causes for Chronic Fatigue Syndrome, Number of B Cells Decreased, Onset of Disease between 25 and 40 Years of Age

  • Infectious Mononucleosis

    fatigue syndrome (CFS), and the risks of exercise at various points in the disease process.[ncbi.nlm.nih.gov] Acute IM is associated with high numbers of EBV-infected B cells, which gradually decrease over time ( 38 ).[dx.doi.org] These include, but are not limited to, infections in the immunocompromised host, AIDS, Lyme disease, osteomyelitis, endocarditis and chronic fatigue syndrome.[hospitals.jefferson.edu]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Chronic Alcoholism

    CONCLUSIONS: AH and AWLD patients display a significantly reduced PB B-cell count, at the expense of decreased numbers of recently produced immature/regulatory B cells and[ncbi.nlm.nih.gov] RESULTS: Patients with AH showed significantly decreased numbers of total PB B lymphocytes (vs. controls and AWLD), at the expense of immature, memory, and, to a lesser extent[ncbi.nlm.nih.gov] The distribution of PB B-cell subsets (immature/regulatory, naïve, CD27(-) and CD27( ) memory B lymphocytes, and circulating plasmablasts of distinct immunoglobulin-Ig-isotypes[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Chronic Fatigue Syndrome

    Research on the pathophysiology and treatment of chronic fatigue syndrome is reviewed. Chronic fatigue syndrome is diagnosed on the basis of symptoms.[ncbi.nlm.nih.gov] , HHV-6 (human herpes virus strain 6), and/or Chlamydia pneumoniae Decreased number of natural killer cells Normal CBC, liver function tests, and normal urinalysis When taken[medicinenet.com] […] homeostasis as indicated by reports of increased CD26 expression [ 120 ], decreased expression of CD69 [ 121 ] and elevated B cell numbers [ 122 ]. (4) A plethora of other[doi.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Obesity

    NKT cells are enriched in normal mouse liver, and their numbers decrease in ob/ob or high-fat diet models of obesity ( 81, 82 ).[doi.org] A wide variety of other immune cells are present in normal liver and may also play roles in inflammation-induced insulin resistance, including T and B lymphocytes, NK cells[doi.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Rheumatoid Arthritis

    An intriguing and hitherto unexplained co-occurrence: Depression and chronic fatigue syndrome are manifestations of shared inflammatory, oxidative and nitrosative (IO&NS)[ncbi.nlm.nih.gov] number of B-cells, a type of immune cell that plays an integral role in causing rheumatoid inflammation and damage.[emedicinehealth.com] ., Haier J 2003 Evidence for Bacterial and Viral Co-Infections in Chronic Fatigue Syndrome Patients. Journal of Chronic Fatigue Syndrome 2003; 11(2):7-20.[charles_w.tripod.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Systemic Lupus Erythematosus

    It is common that patients will be diagnosed with some of the above connective tissue diseases or other conditions such as fibromyalgia or chronic fatigue syndrome before[mollysfund.org] Rituximab is an intravenously infused antibody that suppresses a particular white blood cell, the B cell, by decreasing their number in the circulation.[medicinenet.com] Endogenous CDKN1A mRNA levels measured in Epstein-Barr virus-transformed B cells established from 16 control subjects were linearly correlated with a decreasing copy number[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Sjögren Syndrome

    Komaroff, The Frequency of HLA Class II Antigens in Chronic Fatigue Syndrome, Journal of Chronic Fatigue Syndrome, 11, 4, (33), (2003). Juan-Manuel Anaya, Paula A.[doi.org] Peripheral B cells decreased with a median decrease of 54 and 39% at 6 and 18 weeks, respectively. In conclusion, epratuzumab seems to be an effective treatment.[doi.org] That's because the symptoms can overlap or look like those of other conditions, including chronic fatigue syndrome, fibromyalgia, lupus, rheumatoid arthritis, or even multiple[stlouischildrens.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Chronic Lymphocytic Leukemia

    We describe herein a case of an unusually severe articular syndrome with the use of ibrutinib in a patient with 17 p minus chronic lymphocytic leukemia.[ncbi.nlm.nih.gov] Evidence for on-target toxicity included B cell aplasia as well as decreased numbers of plasma cells and hypogammaglobulinemia.[ncbi.nlm.nih.gov] The most common side effects of Bruton tyrosine kinase inhibitors include fatigue, nausea, diarrhea, bruising, and cytopenias.[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Multiple Myeloma

    The growing number of malignant plasma cells themselves crowd out other healthy blood cells in the bone marrow, resulting in decreased numbers of red blood cells, white blood[themmrf.org] In healthy bone marrow, B cells, a type of white blood cell, develop into antibody-producing plasma cells when antigens enter the body.[themmrf.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Chronic Hepatitis

    […] of natural killer cells in hepatitis B virus related acute-on-chronic liver failure, Clinics and Research in Hepatology and Gastroenterology, 40, 5, (605), (2016).[doi.org] Chronic illnesses that have been reported in rare instances after hepatitis B vaccination include chronic fatigue syndrome ( 171 ), neurologic disorders (e.g., leukoencephalitis[web.archive.org] In rare instances, other illnesses have been reported after hepatitis B vaccination, including GBS, chronic fatigue syndrome, neurologic disorders (e.g. leukoencephalitis,[cdc.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age