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1,759 Possible Causes for Chronic Kidney Insufficiency, Genu Valgum, Some Patients May Be Clinically Asymptomatic

  • Vitamin D Deficiency

    However, severe vitamin D deficiency may manifest as rickets with the below clinical features: Bony Signs - Swelling of wrists and ankles - Leg deformities (genu varum or[starship.org.nz] It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] Vitamin D deficiency/insufficiency is significantly prevalent in chronic kidney disease.[ncbi.nlm.nih.gov]

  • Primary Hyperparathyroidism

    On examination she had bilateral genu valgum.[ncbi.nlm.nih.gov] It is imperative to consider that some patients, such as our patient described in this report, may be previously asymptomatic clinically and on the basis of laboratory findings[ncbi.nlm.nih.gov] Even asymptomatic PHPT patients display clinical improvement in some symptoms a year following PTx, particularly patients with higher preoperative calcium levels ( 2.6 mmol[link.springer.com]

  • Osteomalacia

    Bowing of the legs (genu varum) is typical, but knock knees (genu valgum) can also occur.[patient.info] The absence of short stature and lower limb deformities in some of these patients suggest a not so intense hypophosphatemia during infancy and childhood (53).[scielo.br] Abstract Vitamin D deficiency/insufficiency is significantly prevalent in chronic kidney disease.[ncbi.nlm.nih.gov]

  • Nail-Patella Syndrome

    Other features include: scoliosis genu valgum deformity (due to asymmetrical development of the femoral condyles) flared iliac crests open angle glaucoma 6 prominent tibial[radiopaedia.org] Subjects with achondroplasia can develop genu valgum thought to be the result of ligamentous laxity.[doi.org] Marked genu valgum with lateral instability developed initially unilaterally but subsequently affected both knees.[doi.org]

    Missing: Some Patients May Be Clinically Asymptomatic
  • Adenocarcinoma of the Prostate

    Clinical Presentation Many patients are asymptomatic. Most patients are diagnosed by detection of an elevated Prostate Specific Antigen (PSA) level.[ozradonc.wikidot.com] Some patients may be diagnosed on digital rectal examination.[ozradonc.wikidot.com]

    Missing: Genu Valgum
  • Chronic Pyelonephritis

    Some patients may be asymptomatic while others may present with malaise, fatigue, loss of appetite, loss of weight, cloudy urine, fever, backache, flank pain, or abdominal[symptoma.com] Dangers The disease can develop and damage the kidneys, leading to chronic renal insufficiency.[healthy-inside.com] […] glomerulonephritis 慢性糸球体腎炎 CGN chronic pyelonephritis 慢性腎盂腎炎 chronic renal insufficiency 慢性腎機能不全 chronic kidney disease 慢性腎臓病 CKD chronic kidney disease-mineral and bone[glossary.urol.or.jp]

    Missing: Genu Valgum
  • Cystinosis

    Physical examination revealed severe growth failure and genu valgum. Venous blood gas analysis indicated metabolic acidosis.[adc.bmj.com] He had wide wrists, rachitic rosary, double malleoli and genu valgum, and polyuria at 6 mL/kg/h. The abdomen was protuberant without organomegaly.[sjkdt.org] These include molluscoid pseudotumors (purplish hemorrhagic lesions), skin striae, bone lesions (including osteopenia, compression fractures, scoliosis and genu valgum), leg[procysbihcp.com]

    Missing: Some Patients May Be Clinically Asymptomatic
  • Hypercalcemia

    Clinical surveillance and medical therapy in asymptomatic patients can be considered, and includes appropriate hydration, avoidance of diuretics, replacement of vitamin D[scielo.mec.pt] […] injury or chronic renal insufficiency. 11 For patients with 1-α-hydroxylase–mediated hypercalcemia, glucocorticoid therapy should be considered.[jaoa.org] Moreover, it decreases the risk of nephrolithiasis, increases bone mineral density, and may decrease fracture risk and modestly improve some quality of life measurements.[scielo.mec.pt]

    Missing: Genu Valgum
  • Mucopolysaccharidosis 4A

    MPS-IVA commonly manifests in form of kyphosis or gibbus, scoliosis, pectus carinatum, genu valgum, gait disturbances and frequent falls, but the clinical presentation varies[symptoma.com] […] dL (Chronic kidney disease or CKD3)].[rarediseasesnetwork.org] Skeletal deformities (platyspondyly, kyphosis, scoliosis, pectus carinatum , genu valgum , long bone deformities) become more pronounced as the child grows.[orpha.net]

    Missing: Some Patients May Be Clinically Asymptomatic
  • Familial Hypophosphatemia

    Chronic and more severe forms of hypophosphatemia present with bone pain, osteomalacia and pseudofractures, rachitis-like characteristics (genu valgum, frontal bossing, widening[symptoma.com] […] like osteoporosis and chronic kidney disease, among others [A176041, A176044, F4051].[drugbank.ca] In infants and children, the signs and symptoms include: Abnormal "waddling" walk due to knock-knees (genu valgum) or bowed legs (genu varum) Thick wrists Ribs of the chest[dovemed.com]

    Missing: Some Patients May Be Clinically Asymptomatic

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