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381 Possible Causes for Chronic Lactic Acidosis

  • Acute Alcohol Intoxication

    However, the increase in lactic acid production is small, and severe lactic acidosis in the absence of sepsis or hypotension is rare ( 39, 112, 114, 115 ).[] Clinical Findings Because this disorder is most frequent in chronic alcoholic patients with acute and chronic liver and pancreatic disorders, it may be difficult to distinguish[]

  • Acidosis

    Causes of Metabolic Acidosis Cause Examples High anion gap Ketoacidosis Diabetes Alcohol (chronic abuse) Undernutrition Fasting Lactic acidosis (due to physiologic processes[] Metformin, however, is thought to increase the risk of lactic acidosis, and has been considered to be contraindicated in many chronic hypoxemic conditions that may be associated[] […] with lactic acidosis, such as cardiovascular , renal, hepatic and pulmonary disease, and advancing age.[]

  • Lactic Acidosis

    Here, we present a patient who developed a type B lactic acidosis presumably due to a concurrent chronic myelomonocytic leukaemia.[] Clinical Course of Patient 2, in Whom Hepatic Failure and Severe Lactic Acidosis Developed after Treatment with Fialuridine for Chronic Hepatitis B.[] This causes cell death and is the basic premise of all chronic disease. Nutritional Deficiency Lactic Acidosis Quiz Part 1: Body, Muscles, Arms, Legs 1.[]

  • Hyperuricemia

    […] renal failure Metabolic/endocrine Dehydration, lactic acidosis, ketosis, hypothyroidism Miscellaneous Obesity, toxemia of pregnancy Food with high purine content Organ meats[] lactic acidosis Increased uric acid production High cell turnover ; ( e.g., tumor lysis syndrome, hemolytic anemia, psoriasis, myeloproliferative neoplasms, chemotherapy,[] […] renal failure (any etiology) Metabolic/endocrine Dehydration, lactic acidosis, ketosis, hypothyroidism, hyperparathyroidism Miscellaneous Obesity, sarcoidosis, toxemia of[]

  • Renal Impairment

    We present cases of an elderly woman, a younger woman and a man who developed serious metformin-induced lactic acidosis in the absence of chronic renal impairment.[] […] secondary to metformin accumulation. 1 Other risk factors for lactic acidosis include contrast dye exposure within 48 hours, chronic or excessive alcohol intake, dehydration[] acidosis, including diabetic ketoacidosis Serious hypersensitivity reaction to INVOKANA or metformin WARNINGS and PRECAUTIONS Lactic Acidosis: Postmarketing cases of metformin-associated[]

  • Chronic Alcoholism

    Lactic acidosis Electrolytes. L-Lactate.[] Protein electrophoresis or immunoglobulin quantitation may assist in establishing chronicity. Liver biopsy, if indicated.[]

  • Ileus

    , including lactic acidosis, advanced chronic renal failure, and ingestion of such drugs as salicylate, methanol, ethylene glycol, and paraldehyde.[] Measuring blood lactate concentration easily establishes the diagnosis of lactic acidosis ( 5 mmol/l) because DKA patients seldom demonstrate this level of serum lactate ([] Thus, patients with starvation ketosis rarely present with a serum bicarbonate concentration DKA must also be distinguished from other causes of high anion gap metabolic acidosis[]

  • Gout

    […] renal failure of various etiologies Metabolic/endocrinological Dehydration (often associated with surgery), lactic acidosis, ketosis, hypothyroidism Other Obesity Combined[] […] lysis syndrome Causes of reduced renal urate excretion Drugs Cyclosporine, thiazides, loop diuretics, aspirin (500–1000 mg/d) Renal Hypertension, polycystic kidney disease, chronic[]

  • Gouty Arthritis

    acidosis, alcoholism) Hyperketoacidemia (dg, diabetic ketoacidosis, starvation) Diabetes insipidus (vasopressin-resistant) Bartters syndrome. .. .. .. .. ... 2010[] […] renal failure of various etiologies Metabolic/endocrinological Dehydration (often associated with surgery), lactic acidosis, ketosis, hypothyroidism Other Obesity Combined[] […] idiopathic) Secondary hyperuricemia Increased purine catabolism and turnover Myeloproliferative disorders Lymphoproliferative disorders Carcinoma & sarcoma (disseminated) Chronic[]

  • Hyperkalemia

    Sickle cell) o Adrenal mineralocorticoid deficiency Transcellular shift o Acidosis Eg.[] Causes: Hyperkalaemia as an artefact of collection process or technique Decreased excretion (frequent cause of hyperkalaemia) o Renal diseases: Acute/chronic renal failure[] Diabetic acidocetosis, lactic acidosis Increased production (Most often if in association with renal dysfunction) o Extensive trauma, Rhabdomyolysis (Crush injury, convulsion[]

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