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130 Possible Causes for Chronic Lactic Acidosis, Dark Urine

  • Glycogen Storage Disease Type 2

    lactic acidosis, focal segmental glomerulosclerosis, hepatic adenomas, iron deficiency Diagnosis Deficient G6Pase activity in fresh and frozen liver tissue Case reports 28[pathologyoutlines.com] […] absence of glucose-6-phosphatase, required for gluconeogenesis and glycogenolysis Symptoms: hypoglycemia and marked hepatomegaly in first year of life; later short stature, chronic[pathologyoutlines.com]

  • Blepharoptosis - Myopia - Ectopia Lentis Syndrome

    lactic acidosis Generalized limb muscle atrophy Limitation of joint mobility Large fontanelles Clubbing of fingers Disproportionate tall stature Osteolytic defects of the[mendelian.co] Clinically indistinguishable from Brushfield spots of Down syndrome Name the condition: Acid accumulation in cartilage & tendons Associations: arthropathy, dark urine Ocular[quizlet.com] Congenital onset Eczema Patent ductus arteriosus Increased proportion of HLA DR T cells Pectus excavatum Abnormality of cardiovascular system morphology Flexion contracture Chronic[mendelian.co]

  • Stavudine

    We describe the development of chronic type "B" lactic acidosis in 3 patients receiving stavudine as a single agent and in 2 patients receiving combination therapy with stavudine[ncbi.nlm.nih.gov] Call your doctor at once if you have: stomach pain or swelling, fever, nausea , vomiting , easy bruising or bleeding, loss of appetite, dark urine, or jaundice (yellowing[drugs.com] The median time to the development of lactic acidosis was a little later in our study when compared to another study from South Africa (10.8 months versus 7.5 months) [ 14[bmcinfectdis.biomedcentral.com]

  • Didanosine

    We describe a 49-year-old man with human immunodeficiency virus infection and stable chronic renal insufficiency who developed acute oliguric renal failure and severe lactic[ncbi.nlm.nih.gov] Call your doctor at once if you have: severe pain in your upper stomach (may spread to your back), nausea and vomiting, fast heart rate, itching, loss of appetite, dark urine[emedicinehealth.com] urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).[drugs.com]

  • Glycogen Storage Disease Type 1

    lactic acidosis, focal segmental glomerulosclerosis, hepatic adenomas, iron deficiency Diagnosis Deficient G6Pase activity in fresh and frozen liver tissue Case reports 28[pathologyoutlines.com] More commonly, infants with GSD I tolerate without obvious symptoms a chronic, mild hypoglycemia, and compensated lactic acidosis between feedings.[en.wikipedia.org] Chronic metabolic lactic acidosis and changes in the proximal renal tubule cells can cause osteopenia and rickets with severe skeletal deformities or fractures.[patient.info]

  • Hepatitis B

    Although TDF demonstrates successful viral suppression, the possibility of renal failure and lactic acidosis has been proposed with TDF administration, especially in human[ncbi.nlm.nih.gov] Hepatitis B Electron micrograph of hepatitis B virus Specialty Infectious disease , gastroenterology Symptoms None, yellowish skin , tiredness , dark urine, abdominal pain[en.wikipedia.org] Some people have these symptoms: Yellow skin or eyes No appetite (they don't want to eat) Feeling extremely tired Brown or dark urine (pee) Light or gray stools Pain in the[teensource.org]

  • Myopathy

    Gopinath R, Hutcheon M, Cheema-Dhadli S, Halperin M (1992) Chronic lactic acidosis in a patient with acquired immunodeficiency syndrome and mitochondrial myopathy: biochemical[hiv.imedpub.com] urine muscle weakness kidney damage People who are physically active are more likely to have myopathy than people who are sedentary.[healthline.com] Individuals with myopathy also pass dark colored urine, mainly after carrying out intense exercise.[symptoma.com]

  • Disorder of Carbohydrate Metabolism

    lactic acidosis, poor growth Osteoporotic bones, delayed bone age 30 (No Transcript) 31 Glycogen Storage Diseases Nutrition Therapy for Glycogen Storage Diseases Nutrition[powershow.com] After an interval of several hours to 2–3 days, the patient develops jaundice and often dark urine, due to hemoglobinuria.[namrata.co] Other physical symptoms may include chest or stomach pain, muscle cramps, weakness, or urine that is dark purple or reddish in color.[encyclopedia.com]

  • Acetaminophen

    The case we present manifested an anion gap (AG) metabolic acidosis due to a chronic intoxication: acetaminophen (APAP) overuse over a period of weeks.[ncbi.nlm.nih.gov] Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or[uwhealth.org] A take-home message of both papers is that for patients with high anion gap metabolic acidosis without evidence of lactic acidosis or ketoacidosis, paracetamol should be considered[acutecaretesting.org]

  • Acidosis

    Causes of Metabolic Acidosis Cause Examples High anion gap Ketoacidosis Diabetes Alcohol (chronic abuse) Undernutrition Fasting Lactic acidosis (due to physiologic processes[merckmanuals.com] Signs doctors should look for include: Fatigue Anorexia Upper abdominal discomfort Dark urine Yellowing of the skin or eyes (jaundice) Chronic Kidney Disease Researchers from[drugwatch.com] Metformin, however, is thought to increase the risk of lactic acidosis, and has been considered to be contraindicated in many chronic hypoxemic conditions that may be associated[cochrane.org]

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