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568 Possible Causes for Chronic Myeloid Leukemia, Splenomegaly

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Clinical features are similar to those of the juvenile type of chronic myeloid leukemia. A child with this disease is described.[ncbi.nlm.nih.gov] Studies on NF1 patients with Mo 7-MPD and juvenile chronic myeloid leukemia (JCML) have suggested the role of the NF1 gene in the leukemogenesis.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Interferon has been widely used in the management of patients with hematological malignancies such as polycythemia vera, myelofibrosis, chronic myeloid leukemia and viral[ncbi.nlm.nih.gov] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Those complaints are generally associated with anemia and splenomegaly.[symptoma.com] Abstract ABL1-tyrosine kinase inhibitors (TKIs) have led to dramatic changes in treatment strategies for chronic myeloid leukemia in the chronic phase (CML-CP).[ncbi.nlm.nih.gov] We present a patient with chronic-phase chronic myeloid leukemia who had acute compartment syndrome caused by severe soft tissue bleeding in her right forearm.[ncbi.nlm.nih.gov]

  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] Dasatinib (D) versus high dose imatinib (IM) in patients (pts) with chronic phase chronic myeloid leukemia (CP-CML) resistant to imatinib.[web.archive.org] […] leukemia (T-PLL) is the most common type of mature T-cell leukemia and is characterized by a rapidly rising peripheral blood lymphocyte count, bone marrow involvement, and splenomegaly[web.archive.org]

  • Polycythemia Vera

    […] symptoms in the phase 3 RESPONSE study of patients with polycythemia vera with splenomegaly who experienced an inadequate response to or adverse effects from hydroxyurea.[ncbi.nlm.nih.gov] […] murine leukemia viral oncogene homolog 1-positive chronic myeloid leukemia and polycythemia vera.[ncbi.nlm.nih.gov] […] efficacy and safety of ruxolitinib with the best available therapy (BAT) in hydroxyurea-resistant/hydroxyurea-intolerant polycythemia vera (PV) patients without palpable splenomegaly[ncbi.nlm.nih.gov]

  • Chronic Myelomonocytic Leukemia

    Splenomegaly is frequently seen and may be massive.[ncbi.nlm.nih.gov] , Myeloid, Chronic, Atypical, BCR-ABL Negative/complications* Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative/genetics Leukemia, Myeloid, Chronic, Atypical, BCR-ABL[ncbi.nlm.nih.gov] These patients are vulnerable to hepatic toxicity and graft failure after HSCT because of their increased likelihood of portal hypertension, massive splenomegaly, and extensive[ncbi.nlm.nih.gov]

  • Essential Thrombocythemia

    […] essential thrombocythemia (ET) are myeloproliferative neoplasms respectively characterized by erythrocytosis and thrombocytosis; other disease features include leukocytosis, splenomegaly[ncbi.nlm.nih.gov] While the peripheral blood and bone marrow findings initially suggested essential thrombocythemia, BCR-ABL1 translocation was detected and chronic myeloid leukemia, chronic[ncbi.nlm.nih.gov] This group of disorders include essential thrombocythemia (ET), polycythemia vera (PV), chronic myeloid leukemia, and primary myelofibrosis (PMF), with the respective features[ncbi.nlm.nih.gov]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Splenomegaly of more than 10 cm, basophilia and leukocytosis were associated with a shorter median survival but was not statistically significant.[ncbi.nlm.nih.gov] myeloid leukemia.[ncbi.nlm.nih.gov] The accelerated phase and blast crisis present with fever, splenomegaly, ecchymoses, bleeding, and bone pain.[symptoma.com]

  • Chronic Myeloid Leukemia

    Three of 4 TKI-treated patients did not reach complete hematologic response due to the persistence of thrombocytosis and/or splenomegaly.[ncbi.nlm.nih.gov] What is chronic myeloid leukemia? Chronic myeloid leukemia is a slowly progressing form of blood cancer.[symptoma.com] One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov]

  • Blast Phase

    In this study, we present a JAK2V617F positive MPN patient who experienced fatigue and splenomegaly, transforming into JAK2V617F negative AML.[ncbi.nlm.nih.gov] leukemia, but also in progression of chronic myeloid leukemia.[ncbi.nlm.nih.gov] CASE 4: A 50-yr-old woman was transferred to our hospital with abdominal discomfort and splenomegaly with likely MPAL.[synapse.koreamed.org]

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