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9 Possible Causes for Chronic Non-Infectious Lymphadenopathy

  • Autosomal Dominant Autoimmune Lymphoproliferative Syndrome Type 1

    He presented with multiple non-invasive infections of the skin, that were associated to chronic non-malignant non-infectious lymphadenopathy, failure to thrive, weakness,[ncbi.nlm.nih.gov] A definitive diagnosis is established in the presence of both of the required diagnostic criteria, i.e. chronic non-malignant, non-infectious lymphadenopathy and/or splenomegalyand[orpha.net] The patient presented with the classical symptoms of autoimmune lymphoproliferative syndrome: chronic non-malignant, non-infectious lymphadenopathy, splenomegaly, hepatomegaly[ncbi.nlm.nih.gov]

  • Autoimmune Lymphoproliferative Syndrome Type 3

    Clinical signs present in childhood include fatigue , pallor , bruising, hepatosplenomegaly and chronic , non-malignant, non-infectious lymphadenopathy .[tititudorancea.com] A definitive diagnosis is established in the presence of both of the required diagnostic criteria, i.e. chronic non-malignant, non-infectious lymphadenopathy and/or splenomegalyand[orpha.net]

  • Lymph Node Hyperplasia

    […] lymphomas and, occasionally, chronic lymphocytic leukemia.[aafp.org] EXPOSURES A complete exposure history is essential to determining the etiology of lymphadenopathy.[aafp.org] Exposure to animals and biting insects, chronic use of medications, infectious contacts, and a history of recurrent infections are essential in the evaluation of persistent[aafp.org]

  • Evan's Syndrome

    Diagnostic criteria [ 7 ] Required criteria Chronic ( 6 months), non-malignant, non-infectious lymphadenopathy and/or splenomegaly Elevated CD3 TCRαβ CD4 CD8 DNT cells ( 1.5%[patient.info]

  • Autoimmune Lymphoproliferative Syndrome Type 2A
  • Lymphoproliferative Disorder

    Diagnostic criteria [ 7 ] Required criteria Chronic ( 6 months), non-malignant, non-infectious lymphadenopathy and/or splenomegaly Elevated CD3 TCRαβ CD4 CD8 DNT cells ( 1.5%[patient.info]

  • Hilar Lymphadenopathy

    Tumoral lymphadenopathy includes primary like hodgkin’s and non-hodgkin lymphoma, secondary including metastasis.[medhelp.org] Reactive causes are infection acute bacterial or viral, chronic like tuberculous lymphadentis. Infectious mononucleosis,, toxoplasmosis, etc.[medhelp.org] Like your report mentions these enlarged lymph nodes can be a common symptom of infectious and malignant disease.[medhelp.org]

  • Lymphoproliferative Syndrome 1

    Diagnostic criteria [ 7 ] Required criteria Chronic ( 6 months), non-malignant, non-infectious lymphadenopathy and/or splenomegaly Elevated CD3 TCRαβ CD4 CD8 DNT cells ( 1.5%[patient.info] , non-infectious lymphadenopathy and/or splenomegaly Elevated CD3 TCRαβ CD4 CD8 DNT cells ( 1.5% of total lymphocytes or 2.5% of CD3 lymphocytes) in the setting of normal[casereports.bmj.com] Box 1 Autoimmune lymphoproliferative syndrome (ALPS) diagnostic criteria based on the first international workshop of ALPS 2009 5 Required criteria Chronic ( 6 months), non-malignant[casereports.bmj.com]

  • Cat Scratch Fever

    The differential diagnosis of cat scratch lympadenopathy includes other causes of subacute or chronic lymphadenopathy.[clinicaladvisor.com] Non-infectious diseases that may present with similar manifestations include malignancies and autoimmune diseases.[clinicaladvisor.com] Primarily, this means other granulomatous infections such as Mycobacterium tuberculosis as well as non-tuberculous mycobacteria, fungi, nocardia, and actinomyces.[clinicaladvisor.com]

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