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306 Possible Causes for Circumoral Pallor, Impaired Exercise Tolerance, Pediatric Disorder, Reticulocyte Count Decreased

  • Iron Deficiency Anemia

    Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu] Blood Disorders Center, an integrated pediatric hematology and oncology partnership between Dana-Farber Cancer Institute and Boston Children's Hospital.[childrenshospital.org] Author information 1 Division of Hematology/Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.[ncbi.nlm.nih.gov] The pediatric hematology program at St. Louis Children’s Hospital provides care for all blood disorders, whether noncancerous (benign) or cancerous (malignant).[stlouischildrens.org]

    Missing: Circumoral Pallor
  • Acute Myelocytic Leukemia

    Webb, Acute Myeloid Leukemia and Myelodysplastic Disorders, Pediatric Hematology and Oncology, (95-108), (2010).[doi.org] [PUBMED Abstract] Hasle H: Myelodysplastic and myeloproliferative disorders in children. Curr Opin Pediatr 19 (1): 1-8, 2007.[cancer.gov] Notably, 10.5% of patients with pediatric MDS and GATA2 mutation carried these noncoding variants (Fig. 2 ).[doi.org] [PUBMED Abstract] Occhipinti E, Correa H, Yu L, et al.: Comparison of two new classifications for pediatric myelodysplastic and myeloproliferative disorders.[cancer.gov]

    Missing: Circumoral Pallor
  • Erythema Infectiosum

    , a decrease in the reticulocyte count to less than 1% (usually to 0%) may precipitate TAC.[emedicine.com] Continue reading the main story But the disorders that go by numbers are few and belong to pediatrics. There are as many as six, all with somewhat similar rashes.[nytimes.com] pallor; spares nasolabial folds S/P 1-4d maculopapular rash on extremities, extensor surfaces, trunk (palms/soles us. spared) Gradually fades into lace-like reticular pattern[fprmed.com] The best-known rash of fifth disease is on the face, which becomes intensely red, especially on the cheeks, with a pale ring around the mouth ("circumoral pallor").[drreddy.com]

    Missing: Impaired Exercise Tolerance
  • Anemia

    A normal reticulocyte count confirms that the infant's bone marrow is functional.[aafp.org] One of the most common pediatric disorders, anemia has many potential causes. Anemia is often a symptom of a disease rather than a disease itself.[childrenshospital.org] PATHOGENIC CLASSIFICATION The reticulocyte count is useful to distinguish anemia in which there is an appropriate bone marrow response from that in which there is a decrease[dx.doi.org] In addition to an experienced, compassionate nurse coordinator (who provides your child and family support, education and care coordination), Nemours’ pediatric blood disorder[nemours.org]

    Missing: Circumoral Pallor
  • Aplastic Anemia

    For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow.[labtestsonline.org] Differential diagnosis includes constitutional bone marrow failure syndromes and myelodysplastic disorders.[ncbi.nlm.nih.gov] Food and Drug Administration today approved Promacta (eltrombopag) to treat low blood platelet count in pediatric patients – ages one year and older – with a rare blood disorder[news-medical.net] The doctors who guide your child’s care are board certified in pediatric hematology.[seattlechildrens.org]

    Missing: Circumoral Pallor
  • Myelodysplasia

    Sometimes, pediatric MDS can be associated with other rare conditions, such as inherited bone marrow failure disorders and other rare congenital disorders.[danafarberbostonchildrens.org] Visit your pediatric oncology team for management and treatment of a variety of conditions including: Childhood cancers Blood cancers Bleeding and clotting disorders Long-term[sanfordhealth.org] , multidisciplinary teams at diagnosing and treating pediatric MDS.[childrenshospital.org] Over the last three years we have collected information on over 150 patients with MDS and BMF disorders.[danafarberbostonchildrens.org]

    Missing: Circumoral Pallor
  • Severe Aplastic Anemia

    Monomorphic plasmacytoma-type posttransplant lymphoproliferative disorder (PTLD) has not been reported after pediatric hematopoietic stem cell transplantation.[ncbi.nlm.nih.gov] In SAA patients, complete blood count and reticulocyte count usually reveal pancytopenia and decreased levels of reticulocytes; lymphopenia is rare.[symptoma.com] Aplastic Anemia Treatment at Dana-Farber/Boston Children's Children and young adults with aplastic anemia are treated at Dana-Farber/Boston Children's Cancer and Blood Disorders[childrenshospital.org] Jude Children's Research Hospital, and Department of Pediatrics, College of Medicine, University of Tennessee, Memphis, TN, USA Abstract Introduction Material and Methods[scielo.br]

    Missing: Circumoral Pallor
  • Hypoglycemia

    Abstract CHARGE syndrome is a rare autosomal dominant disorder involving multiple organs.[ncbi.nlm.nih.gov] Pediatrics 1990;85:834-837. Cornblath M, Schwartz R. Disorders of Carbohydrate Metabolism in Infancy. 3rd ed. Philadelphia: W.B. Saunders, 1991, pp. 87-124, 225-246.[uichildrens.org] Forsyth, “Unifying the definitions of sudden unexpected death in epilepsy”: A pediatric perspective, Epilepsia, 53, 6, (1109-1110), (2012).[doi.org] […] and Development, Tokyo, Japan. 3 Division of Pediatric Endocrinology and Metabolism, Children's Medical Center, Osaka City General Hospital, Osaka, Japan. 4 Department of Pediatrics[ncbi.nlm.nih.gov]

    Missing: Circumoral Pallor Reticulocyte Count Decreased
  • Scarlet Fever

    Pediatr Clin North Am 56:1421–1440 CrossRef PubMed Google Scholar Baddour LM, Bisno AL (1982) Recurrent cellulitis after saphenous venectomy for coronary bypass surgery.[doi.org] In addition to this flushed appearance, there is usually a pale area around their mouth (circumoral pallor).[atsu.edu] Signs Forehead and cheeks appear flushed Circumoral pallor Pharyngitis Tonsil s are hyperemic and edematous, with exudate Throat is inflamed and covered by a membrane Palatal[fpnotebook.com] pallor.[symptoma.com]

    Missing: Impaired Exercise Tolerance Reticulocyte Count Decreased
  • Klinefelter Syndrome

    disorders, resulting in a rise in the diagnosis and early referral to the pediatric endocrinologist.[ncbi.nlm.nih.gov] Androgen deficiency disorders. In: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Adult and Pediatric. 7th ed.[nlm.nih.gov] The pediatrician's role in the diagnosis and management of autistic spectrum disorder in children. Pediatrics, 107 (5), 1221-1226.[nichd.nih.gov] Consensus statement on management of intersex disorders. Pediatrics. 2006; 118 (2):e488–e500. [ PubMed ] [ Google Scholar ] 5. Hughes IA, Houk C, Ahmed SF, Lee PA.[ncbi.nlm.nih.gov]

    Missing: Circumoral Pallor Impaired Exercise Tolerance

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