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56 Possible Causes for Clay-Colored Stool, Enlargement of the Spleen, Malabsorption Syndrome

  • Primary Biliary Cirrhosis

    […] shrinking of the testicles, and breast swelling Easy bruising and abnormal bleeding, most often from swollen veins in the digestive tract Confusion or problems thinking Pale or clay-colored[nlm.nih.gov] Complications from Primary Biliary Cirrhosis can include hypersplenism (enlargement of the spleen), hepatic encephalopathy (confusion or coma resulting from liver failure)[disability-benefits-help.org] Therefore CD is always considered as a differential diagnosis for malabsorption syndrome and iron-deficiency anemia, but it is often overlooked as a differential diagnosis[doi.org]

  • Primary Sclerosing Cholangitis

    Symptoms may include: Pain in the right upper quarter of the abdomen Fever Chills Jaundice (yellowing of the skin and eyes) Clay-colored stools Dark urine Low blood pressure[hopkinsmedicine.org] These include: an enlarged liver or spleen, anaemia , cirrhosis , female sex and older age. Increasing bilirubin also correlates with disease progression.[myvmc.com] As the disease progresses, there can be fat-soluble vitamin malabsorption caused by a decrease in the biliary secretion of bile acids.[clevelandclinicmeded.com]

  • Cholestasis

    Malabsorption Syndromes also often arise as a consequence of cholestasis as GI Lipid Absorption requires bile acids.[pathwaymedicine.org] Jaundice and Intrahepatic cholestasis of pregnancy (ICP) The increased build-up of bilirubin leads to jaundice, dark colored urine and pale white clay colored stool.[news-medical.net] […] of the liver and spleen that is not normal Fatigue (tired all of the time) Poor feeding, upset belly, and throwing up Problems that may arise include: Problems absorbing[cincinnatichildrens.org]

  • Progressive Familial Intrahepatic Cholestasis

    The elder sibling also demonstrated symptoms including acholic stools and failure to thrive.[wjgnet.com] […] liver and spleen (hepatosplenomegaly).[ghr.nlm.nih.gov] It can be performed without inducing clinical signs of fat malabsorption although individualized supplementation of fat-soluble vitamins with careful monitoring is warranted[ncbi.nlm.nih.gov]

  • 3Beta-Hydroxy-Delta5-C27-Steroid Oxidoreductase Deficiency

    Affected individuals may also exhibit diarrhea, excess fats in the stools (steatorrhea), and pale or clay-colored stools due to the suppression of bile flow (acholic stools[rarediseases.org] Other than that, the spleen and liver are enlarged, fat is accumulated in the stool and vitamin deficiencies cause various other symptoms.[symptoma.com] […] include progressive familial intrahepatic cholestasis, diseases that present with neonatal cholestasis, which includes alpha-1-antitrypsin deficiency of ZZ phenotype, Alagille syndrome[malacards.org]

  • Cystic Fibrosis

    […] that are pale or clay-colored , foul smelling, have mucus, or that float Weight loss Symptoms related to the lungs and sinuses may include: Coughing or increased mucus in[nlm.nih.gov] This is because by the time liver disease is evident in a person with an enlarged liver or spleen, there is often already raised pressure in the large vein running through[doi.org] Both diseases may present the intestinal malabsorption syndrome and similar clinical manifestations that contribute to difficulties with clinical distinction.[ncbi.nlm.nih.gov]

  • Whipple Disease

    Other symptoms associated with Whipple’s disease include: Fever Anemia Fatigue Chest pain Pericarditis Heart failure Chronic cough Lung disorders Enlarged spleen Difficulty[hxbenefit.com] Differential diagnosis The differential diagnosis includes seronegative polyarthritis, ankylosing spondylitis, culture-negative endocarditis, vasculitis, malabsorption syndrome[orpha.net] Summary Background Whipple's disease (WD) is rarely the cause of a malabsorption syndrome.[ncbi.nlm.nih.gov]

  • Pancreatic Adenocarcinoma

    Symptoms of pancreatic cancer include: Diarrhea Dark urine and clay-colored stools Fatigue and weakness Sudden increase in blood sugar level (diabetes) Jaundice (a yellow[nlm.nih.gov] […] in enlargement of the spleen (splenomegaly).[merckmanuals.com] Common presenting symptoms include epigastric pain that radiates to the back, unexplained weight loss, painless jaundice, light clay-colored stools, dark urine, pruritus,[nature.com]

  • Malabsorption Syndrome

    […] and in scars  Chest pain  Enlarged spleen 87.[slideshare.net] Malabsorption syndromes commonly result from a pathological interference of the normal digestive process. There have been major advances in the last 4 years.[ncbi.nlm.nih.gov] CONCLUSIONS: Primary systemic amyloidosis should be considered in the differential diagnosis of malabsorption syndrome.[ncbi.nlm.nih.gov]

  • Pancreatectomy

    Step 6: Dissection of distal pancreas and spleen in an avascular plane from retroperitoneum .[sages.org] The pancreatic tail (with or without the spleen) is put into a leak-proof retrieval bag and extracted using a Pfannenstiel incision or an enlarged trocar incision.[trialsjournal.biomedcentral.com] Step 7: Bagging the specimen and retrieval by enlarging the umbilical port site. Operative video is presented.[sages.org]

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