Clinodactyly: Causes & Reasons

Possible Causes for Clinodactyly

Occasional features include short thumbs, fifth finger clinodactyly, malformed cervical vertebrae and mild mental retardation. [ncbi.nlm.nih.gov]

Patient was asymptomatic up to 30 months of age and presented bilateral hallux valgus deformities and clinodactyly. [jped.com.br]

[…] lesions and avoid additional diagnostic procedures, including biopsy.2 Download figure Open in new tab Download powerpoint Figure Radiologic findings Skeletal X-rays show clinodactyly [n.neurology.org]

Andersen-Tawil Syndrome

Figure (A) Fifth digit clinodactyly and (B) syndactyly of the toes 2 and 3, highly suggestive of Andersen-Tawil syndrome. [scielo.br]

[…] of the 5th finger Permanent curving of the pinkie finger 0004209 Clinodactyly of the 5th toe 0001864 Delayed eruption of permanent teeth Delayed eruption of adult teeth 0000696 [rarediseases.info.nih.gov]

Neuro-Psiquiatr. vol.72 no.11 São Paulo Nov. 2014 http://dx.doi.org/10.1590/0004-282X20140168 Images in Neurology Clinodactyly and syndactyly – diagnostic clues for Andersen-Tawil [scielo.br]

Tel Hashomer Camptodactyly Syndrome

He also had proximal cutaneous syndactyly of all fingers, clinodactyly of the fifth fingers, brachydactylous thumbs, and tapering of fingers. [vdocuments.site]

Winging scapulae, scoliosis, syndactyly and clinodactyly are commonly observed. [malacards.org]

Winging scapulae, scoliosis, syndactyly and clinodactyly are commonly observed. The affected patients usually have normal mental development. [orpha.net]

Russell-Silver Syndrome

Fifth finger clinodactyly is a common finding and can be detected by US ( Figs. 54.4 and 54.5 ). [radiologykey.com]

Fifth finger clinodactyly and syndactyly of toes are observed. [accessanesthesiology.mhmedical.com]

[…] short stature of prenatal onset, triangular facies, asymmetry, variations in the pattern of sexual development, and other abnormalities, such as cafe-au-lait pigmentation, clinodactyly [ncbi.nlm.nih.gov]

Aarskog-Scott Syndrome

Findings on the extremities include joint hyperextensibility, short and broad hands, interdigital webbing, a short fifth finger, clinodactyly and broad feet with bulbous toes [ncbi.nlm.nih.gov]

[…] nares Nasal tip, upturned Upturned nose Upturned nasal tip Upturned nostrils [ more ] 0000463 Broad forehead Increased width of the forehead Wide forehead [ more ] 0000337 Clinodactyly [rarediseases.info.nih.gov]

[…] hypertelorism, short nose with anteverted nares, maxillary hypoplasia, a crease below the lower lip, mild interdigital webbing with short and broad hands, short fifth finger with clinodactyly [ncbi.nlm.nih.gov]

Kleiner Holmes Syndrome

[…] of the skeletal system and Clinodactyly that can help you solving undiagnosed cases. [mendelian.co]

The propositus had clinodactyly of both fifth fingers. Radiographs showed that the first metatarsals and phalanges of both great toes were broad, short, and misshapen. [omim.org]

Diseases related with Abnormality of the skeletal system and Clinodactyly In the following list you will find some of the most common rare diseases related to Abnormality [mendelian.co]

Mesoaxial Synostotic Syndactyly with Phalangeal Reduction

[…] characterized by mesoaxial osseous synostosis at a metacarpal level, reduction of one or more phalanges, hypoplasia of distal phalanges of preaxial and postaxial digits, clinodactyly [uniprot.org]

The limb findings include mesoaxial reduction of the fingers, synostoses of the third and fourth metacarpals with associated single phalanges, fifth finger clinodactyly, and [ncbi.nlm.nih.gov]

[…] syndactyly of the 3rd and 4th fingers with synostoses of the corresponding metacarpals and associated single phalanges, syndactyly of the 2nd and 3rd toes and 5th finger clinodactyly [rarediseases.info.nih.gov]

Polydactyly of a Biphalangeal Thumb

Observe also mesopha- duplication of the distal phalanx of the thumb, bifid proximal langism with clinodactyly of the 5th finger. [rrnursingschool.biz]

[…] hypotonia, brachycephaly, upslanting palpebral ï¬ssures, ï¬at nasal bridge, low-set ears, a single transverse palmar crease in the right hand, bilateral ï¬fth ï¬nger clinodactyly [deepdyve.com]

The appearance can differ widely; the thumb can be a longer thumb, it can be deviated in the radio-ulnar plane ( clinodactyly ), thumb strength can be diminished. [en.wikipedia.org]

Banki Syndrome

Resource Review It Rate It Bookmark It Added: Sat Aug 08 2009 Clinodactyly Wikipedia Location: http://en.wikipedia.org/wiki/Clinodactyly Clinodactyly is a medical term describing [orthopaedicweblinks.com]

[…] to:navigation, search Banki syndrome is a synostosis syndrome, reported in a single Hungarian family in which members of 3 generations showed lunotriquetral synostosis, clinodactyly [bugsigdb.org]

As such no treatment is required for clinodactyly. [m.athena.targetwoman.com]

Short Stature due to Endocrine Disorder

[…] include variable degrees of intellectual deficit, microcephaly and dysmorphism (broad nasal bridge and tip, smooth philtrum, thin upper and everted lower lips, short fingers, clinodactyly [orpha.net]

[…] nasal tip Increased breadth of tip of nose Increased width of nasal tip Increased width of tip of nose Nasal tip, broad Nasal tip, wide Wide tip of nose [ more ] 0000455 Clinodactyly [rarediseases.info.nih.gov]

[…] is not available through HPO Abnormality of metabolism/homeostasis Laboratory abnormality Metabolism abnormality [ more ] 0001939 Autosomal recessive inheritance 0000007 Clinodactyly [rarediseases.info.nih.gov]

Brachydactyly

Wertelecki, M.D.) see finger malformations namely short tips and nails (brachydactyly), clinodactyly (deviation) of the third finger. [ceo.medword.net]

He had short little, index, and middle fingers, long ring fingers, and clinodactyly of the little finger. He also had symmetrical brachydactyly of both feet. [ncbi.nlm.nih.gov]

Figure 7 Hands of 103, one of the indeterminate group, showing small hands but no disproportion or clinodactyly. [jmg.bmj.com]

Oculodentodigital Dysplasia

Both hands showed camptodactyly, clinodactyly and brachydactyly of 5th finger. [ncbi.nlm.nih.gov]

The proband suffered with extensive enamel hypoplasia, polysyndactyly and clinodactyly of the 3rd-5th fingers, microphthalmia, and unique facial characteristics of ODDD. [ncbi.nlm.nih.gov]

The syndrome is characterized by abnormal facial features, central nervous system involvement, syndactyly and clinodactyly of fourth and fifth fingers, dry and lusterless [ncbi.nlm.nih.gov]

Gorlin-Psaume Syndrome

[…] lobulated or bifid tongue, cleft or pseudocleft palate, tongue tumours, missing or malpositioned teeth, hypoplastic nasal alar cartilage, depressed nasal bridge, brachydactyly, clinodactyly [kmle.co.kr]

[…] orpostaxiaipolydactyly;brachydactyly;clinodactyly;syndactyiyPreaxialpoiydactylyCerebellaranomalies;Dandy-WalkeranomalyAutosomalrecessiveOFDS 7(Whelansyndrome)Highly arched [docslide.us]

[…] malformations of- *Face (facial asymmetry, hypoplastic mandible, hypertelorism) *Oral cavity (cleft lip and palate, lobulated tongue, abnormal dentition) *Digits (brachydactyly, clinodactyly [eurorad.org]

Brachydactyly of Fingers

CLINODACTYLY Image 19 Clinodactyly of the 5th finger of the hand. Image 20 Photo 1 and 2: Hand with radial deviation of the 5° finger and cubital deviation of the 4°. [en.atlaseclamc.org]

The finger deviation is a type of clinodactyly as I have previously discussed. http://congenitalhand.wustl.edu/search? [congenitalhand.wustl.edu]

Camptodactyly/Clinodactyly (bent digits) – Treatment Camptodactyly and clinodactyly are two congenital conditions causing bent fingers that are not passively correctible. [baysideplasticsurgery.com.au]

Hand-Foot-Genital Syndrome

Haploinsufficiency for HOXA13 in humans causes Hand-foot-genital syndrome (HFGS), which is characterized by symmetric preaxial deficiency of the hands and feet, second and fifth finger clinodactyly [oxfordmedicine.com]

We report a child born with bilateral postaxial syndactyly of the feet and bilateral fifth finger clinodactyly. [ncbi.nlm.nih.gov]

3M Syndrome

Clinodactyly is a frequent finding in SRS and persists in the older age group. [omicsonline.org]

Affected individuals may also have additional abnormalities including permanent fixation of certain fingers in a bent position (clinodactyly), unusually short fifth fingers [healthetreatment.com]

They all showed numerous dysmorphisms, such as triangular face with prominent forehead, large eyes, depressed nasal bridge, thin upper lip, short neck, and bilateral clinodactyly [cags.org.ae]

Autosomal-Recessive Robinow Syndrome

Mesomelia (HP:0003027), Brachydactyly syndrome (HP:0001156), Clinodactyly (HP:0030084) Broad first toe (HP:0001837). [databases.lovd.nl]

Aplasia/Hypoplasia involving the metacarpal bones ; Autosomal recessive inheritance ; Bifid distal phalanx of toe ; Bifid tongue ; Brachydactyly ; Broad thumb ; Broad toe ; Clinodactyly [mousephenotype.org]

[…] facial features (hypertelorism, midface hypoplasia, large nasal bridge, short upturned nose, and anteverted nares), mesomelic limb shortening, as well as brachydactyly, clinodactyly [orpha.net]

Dubowitz Syndrome

Further findings include hyperactivity, eczema, cryptorchidism in the affected males, and brachy-clinodactyly of the fifth fingers. [ncbi.nlm.nih.gov]

Skeletal abnormalities in DS include sacral dimple, and clinodactyly (5th fingers), with cutaneous syndactyly of toes or fingers. [orpha.net]

Majewski Medicine European Journal of Pediatrics 2004 Findings include hyperactivity, eczema, cryptorchidism in the affected males, and brachy-clinodactyly of the fifth fingers [semanticscholar.org]

Robinow Syndrome

Clinodactyly of fifth finger Cone-shaped epiphysis Congenital fused vertebrae Congenital heart disease Congenital macrocephaly Congenital narrow spinal canal Congenital renal [gamuts.net]

It is characterized by mesomelic brachymelia, hemivertebrae, dysmorphic facies, genital hypoplasia, micropenis, clinodactyly, camptodactly, hypoplastic nails and moderate [ncbi.nlm.nih.gov]

[…] syndrome were hypertelorism, nasal features (large nasal bridge, short upturned nose, and anteverted nares), midface hypoplasia, mesomelic limb shortening, brachydactyly, clinodactyly [ncbi.nlm.nih.gov]

Humero-Radial Synostosis

[…] with delta phalanx Clinodactyly, with no delta phalanx Congenital abnormal fusion of carpal bone Congenital abnormal fusion of humerus Congenital abnormal fusion of metacarpal [emedcodes.com]

[…] of right finger Madelung's deformity Madelungs deformity Radioulnar synostosis Right camptodactyly Right clinodactyly Right congenital clinodactyly Right radioulnar synostosis [icd10data.com]

Radial clinodactyly of thumb. 5. [de.slideshare.net]

XXXXY Syndrome

A two month-old boy with intrauterine growth restriction (IUGR) and low birth weight, facial dysmorphism, clinodactyly in feet, microphallus, and right undescendent testis [ncbi.nlm.nih.gov]

Case: A two month-old boy with intrauterine growth restriction (IUGR) and low birth weight, facial dysmorphism, clinodactyly in feet, microphallus, and right undescendent [journals.ssu.ac.ir]

In addition, almost all patients had muscular hypotonia, radioulnar synostosis, white matter anomalies, fifth-finger clinodactyly, recurrent respiratory infections in early [ncbi.nlm.nih.gov]

Pseudoaminopterin Syndrome

[…] hypertelorism, palpebral fissure anomalies, micrognathia cleft lip and/or high arched palate and small and low set/rotated ears.Limb anomalies include brachydactyly, syndactyly and clinodactyly [ncbi.nlm.nih.gov]

[…] of both 4th and 5th fingers; hypoplasia of the 4th metacarpal and clinodactyly of the 4th and 5th toes; overlap of the second over the third toe; bilateral hip luxation; [ncbi.nlm.nih.gov]

Macrocephalus Microcephaly Micrognathia Narrow forehead Narrow palpebral fissure Oligodontia Underdeveloped supraorbital ridges Abnormality of limbs Arachnodactyly Brachydactyly Clinodactyly [ncbi.nlm.nih.gov]

Distal Symphalangism

Etiology and Epidemiology Clinodactyly Clinodactyly by definition is >10 degrees of digital deviation in the radioulnar plane. [musculoskeletalkey.com]

[…] of the 5th finger Syndactyly Clinodactyly SOURCES: GARD SCTID MONDO MESH UMLS OMIM ORPHANET More info about SYNDACTYLY, MESOAXIAL SYNOSTOTIC, WITH PHALANGEAL REDUCTION; MSSD [mendelian.co]

[…] part of a spectrum of disorders that cause joint fusion, with multiple synostoses syndrome being at the most severe end of this spectrum 4 Brachydactyly, camptodactyly, clinodactyly [handsurgeryresource.com]

Drayer Syndrome

[…] syndrome characterized by pre- and postnatal growth restriction, developmental delay, variable degrees of intellectual disability, hand and foot anomalies (e.g. brachy-/clinodactyly [orpha.net]

Weigh: 4750g,-3.46SDS;Heigh:53 cm,-5.56SDS;OFC:38.5 cm,<Pc3.At birthW:2500g,-1.8SDS;H:41cm,-5.3SDS.Al physical exam:triangular facies,low-set ears,small hands, clinodactyly [conicet.gov.ar]

OSLAM Syndrome

Clinodactyly The picture above illustrates a severe case of this condition. [en.wikipedia.org]

Orpha Number: 2760 Definition OSLAM syndrome is characterised by the association of osteosarcoma, limb anomalies (clinodactyly with brachymesophalangy, bilateral radioulnar [malacards.org]

[…] portal for information on rare diseases and orphan drugs.Orpha Number: 2760DefinitionOSLAM syndrome is characterised by the association of osteosarcoma, limb anomalies (clinodactyly [malacards.org]

Klinefelter Syndrome with Male Phenotype with more than Two X Chromosomes

Our patient also had clinodactyly of the third finger and showed finger clubbing in all fingers and toes (Fig. 2). [jmedicalcasereports.biomedcentral.com]

[…] certain bones in the forearm (radioulnar synostosis), an unusually large range of joint movement (hyperextensibility), elbow abnormalities, curved pinky fingers (fifth finger clinodactyly [malacards.org]

Postaxial Oligodactyly, Tetramelic

[…] of the 5th finger Syndactyly Clinodactyly SOURCES: GARD SCTID MONDO MESH UMLS OMIM ORPHANET More info about SYNDACTYLY, MESOAXIAL SYNOSTOTIC, WITH PHALANGEAL REDUCTION; MSSD [mendelian.co]

[…] radial head, one-bone forearm operation, thumb/first web space reconstruction, forearm lengthening, and other procedures such as correction of concurrent syndactyly and clinodactyly [link.springer.com]

[…] hearing impairment Cerebellar hypoplasia Aggressive behavior Growth delay Muscular hypotonia Strabismus Inguinal hernia X-linked recessive inheritance Patent ductus arteriosus Clinodactyly [mendelian.co]

Mohr Syndrome

Both hands have clinodactyly and preaxial polydactyly as there are 7 fingers (duplicate thumb). There is also syndactyly between thumbs (bifid thumb) in each hand. [aclr.com.es]

[mor] Etymology: Otto Lous Mohr, Norwegian geneticist, 1886-1967 an autosomal recessive disorder characterized by brachydactyly, clinodactyly, polydactyly, syndactyly, and [medical-dictionary.thefreedictionary.com]

Furthermore, the digital abnormalities include pre- and post-axial polydactyly of the hands and feet, partial bilateral duplication of the hallux, syndactyly, clinodactyly [symptoma.com]

Craniofrontonasal Dysplasia

[…] lip and/or palate, high arched palate), skeletal anomalies (clavicle pseudoarthrosis, coronal craniosynostosis, various digital and limb anomalies including syndactyly, clinodactyly [orpha.net]

[…] defect of the nose Abnormality of the clavicle Abnormality of the palate Abnormality of the shoulder Abnormality of the teeth Brachydactyly syndrome Camptodactyly of finger Clinodactyly [familydiagnosis.com]

Clinodactyly of both the fifth toe was obvious [Figure 1c]. Fingers of the hands were long with relatively broad thumb. [mjdrdypu.org]

Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

0002750 5 joint hyperflexibility 60 33 hallmark (90%) Very frequent (99-80%) HP:0005692 6 mitral valve prolapse 60 33 hallmark (90%) Very frequent (99-80%) HP:0001634 7 clinodactyly [malacards.org]

Short nose Short finger Short distal phalanx of finger Sparse eyelashes Triangular face Hypoplasia of teeth Failure to thrive Narrow naris Overgrowth Dental malocclusion Clinodactyly [mendelian.co]

Bony abnormalities include pectus excavatum, an inward bend of the small finger (clinodactyly), and an inward point of the great toe. [ibis-birthdefects.org]