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116 Possible Causes for Clitoromegaly, Testosterone Increased

  • Virilization

    OBJECTIVE: To describe a rare case of 45,X Turner's syndrome with elevated T and clitoromegaly caused by ovarian hilus cell hyperplasia. DESIGN: Case report.[ncbi.nlm.nih.gov] What abnormality causes a marked testosterone increase without much DHEA increase? What abnormality causes a marked DHEA increase without much testosterone change?[quizlet.com] We report a typical case that we found at cesarean section to be associated with a virilized infant who manifested clitoromegaly and labial fusion.[ncbi.nlm.nih.gov]

  • Testosterone

    We describe an 11.5-year-old girl with a 9-month history of voice deepening, mild hirsutism, minor acne, increased growth velocity, weight gain, and clitoromegaly.[ncbi.nlm.nih.gov] The increase in receptor density is also unlikely to be a consequence of the lipophilicity of testosterone.[doi.org] Sartori Sanchez Bachega and Andrea Dardis , The Presence of Clitoromegaly in the Nonclassical Form of 21-Hydroxylase Deficiency Could Be Partially Modulated by the CAG Polymorphic[doi.org]

  • Adrenogenital Syndrome

    Abstract For preservation of postoperative sensitivity of the glans clitoris, clitoroplasty for clitoromegaly due to adrenogenital syndrome is reported.[ncbi.nlm.nih.gov] Thus 17-hydroxyprogesterone, androstenedione and testosterone levels are increased.[myvmc.com] A 23-year-old Japanese woman had her male-like musculature, hirsutism, the absence of breast development and marked clitoromegaly.[ncbi.nlm.nih.gov]

  • Polycystic Ovary Syndrome

    […] must be carefully searched for, since they draw the clinician’s attention toward a severe disease: (a) rapidly growing hirsutism, with other signs of virilization such as clitoromegaly[web.archive.org] Moreover, a more significant decrease of total testosterone and increase of SHBG serum levels were noticed in Group A.[ncbi.nlm.nih.gov] Occasionally, clitoromegaly, increased muscle mass, deep voice (more usually, these are signs of more severe hyperandrogenism syndromes).[patient.info]

  • Ovarian Androblastoma

    […] and Symptoms (Pathophysiology) Symptoms can include infrequent or no menstrual periods, the development of facial hair, a hoarse voice, increased muscle mass, acne, and clitoromegaly[knowcancer.com] Hormonal studies reveal an increase in the amount of LH (characteristic of techopolystosis), a high level of testosterone with a slight increase in the excretion of 17-KS[en.medicine-guidebook.com] Additional signs include acne and hirsutism , voice deepening, clitoromegaly , temporal hair recession, and an increase in musculature. Serum testosterone level is high.[en.wikipedia.org]

  • Androgen Therapy

    Recent studies have shown that physiologic testosterone replacement in HIV-infected men with weight loss who have low testosterone levels can also increase muscle mass and[ncbi.nlm.nih.gov] Liver Damage Testosterone is metabolized in the liver and use of testosterone and other hormones has been shown to increase liver enzyme levels.[drugdangers.com] The predicted adult height before and 2 years after completion of treatment remained unchanged in the two testosterone groups.[ncbi.nlm.nih.gov]

  • 17-Hydroxycorticosteroid

    Conversion of pregnenolone to progesterone is impaired, blocking synthesis of both cortisol and aldosterone but increasing adrenal androgens .[dermnetnz.org] In females, these weak androgens produce partial virilisation . 3β-hydroxysteroid dehydrogenase deficiency reduces testosterone production in the male testis so that the genitals[dermnetnz.org] Males present with ambiguous external genitalia or appear to be female (male pseudohermaphroditism). 17-hydroxylase deficiency causes decreased production of cortisol and increased[dermnetnz.org]

  • Leydig Cell Tumor

    They are most often diagnosed in premenopausal women and may produce androgens, resulting in hirsuitism, voice deepening, frontal balding, terminal hair growth, and clitoromegaly[ncbi.nlm.nih.gov] Almost all of these boys present with isosexual precocious pseudopuberty associated with increased testosterone, low gonadotropin levels and a testis mass.[ncbi.nlm.nih.gov] These tumors usually present virilizing symptoms such as oligomenorrhea or amenorrhea, hirsutism, voice raucity, laryngeal protuberance and clitoromegaly.[ncbi.nlm.nih.gov]

  • Anabolic Steroid

    In addition, AAS abuse resulted in structural and functional sperm changes, a reduction in testicular volume, gynecomastia, as well as clitoromegaly, menstrual irregularities[ncbi.nlm.nih.gov] Chemical substitutions on the testosterone molecule cause increased potency and duration of action.[ncbi.nlm.nih.gov] Signs of Anabolic Steroid Abuse in Women Acne Hirsutism Deepening of the voice Male pattern balding Clitoromegaly Breast atrophy Irregular menstrual cycles Infertility Significant[acog.org]

  • Androgen Insensitivity Syndrome

    The subtle effects of AR mutations present in a patient with micropenis, peno-scrotal hypospadias, infertility, clitoromegaly and posterior labial fusion.[ncbi.nlm.nih.gov] Basal LH and testosterone values are highly variable and might not be increased during early infancy.[doi.org] […] androgen insensitivity syndrome (PAIS), several different phenotypes are evident with predominantly female phenotype to ambiguous genitalia (determined by the extent of clitoromegaly[link.springer.com]

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