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292 Possible Causes for Clonus, Hyperreflexia, Muscle Twitch

  • Spinal Cord Injury

    Upper motor neurone signs in the lower limbs (Babinski's sign: up-going plantar reflex, hyperreflexia, clonus, spasticity).[patient.info] Spasticity is characterized as hyperreflexia and hypertonicity as a result of damage to the supraspinal tracts in the aftermath of SCI.[ncbi.nlm.nih.gov] This eventually leads to muscle weakening, twitching, and an inability to move the arms, legs, and body. The condition slowly gets worse.[neuralstem.com]

  • Myelopathy

    […] with radicular symptoms - 16% had pure myelopathic symptoms - 23% had a combination of myelopathic and radiculopathy - upper motor neuron findings such as hyper-reflexia, clonus[wheelessonline.com] Clinical hyperreflexia was tested at the MCP joint, using a six-axis load cell.[ncbi.nlm.nih.gov] Motor weakness in the extremities Gait difficulties ("spastic gait," hesitant and jerky) Myelopathic or "upper motor neuron" findings such as spasticity, hyperreflexia, clonus[emoryhealthcare.org]

  • Lithium Toxicity

    […] correlate with the serum lithium level are : 1.5 to 2.5 mEq/L – mild lethargy, mild tremor, and slurred speech 2.5 to 3.5 mEq/L – increasing lethargy, increasing tremors, and clonus[pharmacyjoe.com] There may be tremors in the hand, muscle twitches, slurring of speech, eye movements that are uncontrollable, alterations in the level of consciousness and even coma.[medicalfoxx.com] […] toxicity • Generalized weakness • Fine resting tremor • Mild confusion Moderate-to-severe toxicity • Severe tremor • Muscle fasciculations • Choreoathetosis • Hyperreflexia • Clonus[slideshare.net]

  • Strychnine Poisoning

    The ten main symptoms of strychnine poisoning: Initial symptoms are tightness and twitching of the muscles, agitation and hyperreflexia. Stiffness of the body. Lockjaw.[chm.bris.ac.uk] The skin perception becomes aggravated, a crawling sensation appears, small muscle twitches, numbness, the slightest sound, light - irritate.[en.intoxication-stop.com] Needless to say, a “thumbnail-sized” portion is worrying… Muscle spasms and rigidity generally resolve within 24 hours, although ongoing hyperreflexia and increased tone may[lifeinthefastlane.com]

  • Spinal Cord Infarction

    His motor and sensory exams and reflexes are normal although he does exhibit mild finger clonus. The patient was referred for an MRI of the cervical spine.[radsource.us] Hyperreflexia may follow initial symptoms, and a positive Babinski reflex may be elicited.[symptoma.com] A 48-year-old man with syncope and diffuse muscle twitches. Neurohospitalist. 2012 Jul; 2(3):107-11. PMID: 23983873; PMCID: PMC3726089.[connects.catalyst.harvard.edu]

  • Spinal Cord Lesion

    (spinal cord concussion): - usually invovles 24-72 hour period of paralysis, hypotonia, & areflexia, and at its conclusion there may be hyperreflexia, hypertonicity, and clonus[wheelessonline.com] Autonomic hyperreflexia is a serious peripartum complication associated with spinal cord lesions.[ncbi.nlm.nih.gov] […] reflexly to cause the normally visible muscle twitch.[encyclopedia.com]

  • Subacute Transverse Myelitis

    There was no clonus. Deep tendon reflexes were traced in the upper extremities, 2 at the knees, 2 at the ankles. Toe signs were silent. There was no spine tenderness.[egms.de] An areflexic cystometrogram tended to change to a low compliance bladder, followed by detrusor hyperreflexia or a normal cystometrogram.[nature.com] No ankle clonus was observed. Babinski’s sign was the plantar response. The anal sphincter tone was intact.[karger.com]

  • Tetanus

    Tetanus is a life-threatening neurological syndrome characterised by tonic muscle spasms and hyperreflexia, caused by the exotoxin of Clostridium tetani , a gram-positive[bestpractice.bmj.com] ‘As we normally use our muscles, the individual fibers go into tetanus for brief periods rather than simply undergoing single twitches.’[en.oxforddictionaries.com] ‘At 50 shocks per second, the muscle goes into the smooth, sustained contraction of tetanus.’[en.oxforddictionaries.com]

  • Multifocal Motor Neuropathy

    No clonus, extensor plantar response, or pseudobulbar palsy is present. Pathologic reflexes (eg, Babinski, Hoffman) are not present.[emedicine.medscape.com] Atrophy may be present, but hyperreflexia and spasticity are not seen.[ncbi.nlm.nih.gov] Usually, the arms and hands are affected first and symptoms include muscle weakness, cramps and uncontrollable twitching.[medic8.com]

  • Acute Transverse Myelitis

    Flaccid weakness gradually changes to pyramidal tract signs, with hyperreflexia, clonus, and extensor responses.[pediatricneurologybriefs.com] Neurological Examination: spastic paraplegia, Babinski sign bilateral patellar, hyperreflexia and aquiliana, sensorial level T4.[omicsonline.org] Sx: leg weakness, sphincter dysfunction, abnormal DTRs [acutely may be absent, but hyperreflexia the rule].[hopkinsguides.com]

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