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25 Possible Causes for Clonus, Thenar Muscle Atrophy

  • Cervical Spondylosis

    Objective neurological deficit (upper motor neurone signs in the legs (eg, up-going plantars, hyperreflexia, clonus, spasticity); lower motor neurone signs in the arms (eg[patient.info] […] groups, especially in the extremities poor or pathologic tandem gait atrophy of the hand’s thenar prominence (the fleshy fat pad just superior to the thumb on the ventral[americannursetoday.com] On physical examination, you may find some or many of the following: clonus or spasticity of the lower extremities sensory changes (light touch, pinprick sensation, or temperature[americannursetoday.com]

  • Cervical Myelopathy

    Motor weakness in the extremities Gait difficulties ("spastic gait," hesitant and jerky) Myelopathic or "upper motor neuron" findings such as spasticity, hyperreflexia, clonus[emoryhealthcare.org] […] groups, especially in the extremities poor or pathologic tandem gait atrophy of the hand’s thenar prominence (the fleshy fat pad just superior to the thumb on the ventral[americannursetoday.com] Increased tension in the leg muscles (Hyperreflexia) Accentuated reflexes of the knee and ankle Forced extension of the ankle may cause the foot to beat up and down rapidly (clonus[dr-bertagnoli.com]

  • Cervical Spinal Cord Tumor

    Coming down the stairs or stepping off a curb will reveal ankle clonus felt as “vibrations” by patient.[clinicaladvisor.com] In patients with severe spasticity, ankle clonus is prominent. High cervical cord lesions may produce quadriparesis with diaphragmatic weakness.[clinicaladvisor.com] […] which in the cervical cord will produce more arm over leg weakness, with dissociated sensory loss.Carefully elicited sensory level on the trunk, severe spasticity, ankle clonus[clinicaladvisor.com]

  • Myelopathy

    Physical examination revealed significant increase in deep tendon reflexes in the lower extremities and clonus. Hoffman's sign was positive in the left upper extremity.[ncbi.nlm.nih.gov] […] groups, especially in the extremities poor or pathologic tandem gait atrophy of the hand’s thenar prominence (the fleshy fat pad just superior to the thumb on the ventral[americannursetoday.com] […] with radicular symptoms - 16% had pure myelopathic symptoms - 23% had a combination of myelopathic and radiculopathy - upper motor neuron findings such as hyper-reflexia, clonus[wheelessonline.com]

  • Cervical Herniated Disc

    Upper motor neurone signs in the lower limbs (Babinski's sign - up-going plantar reflex, hyperreflexia, clonus, spasticity).[patient.info]

  • Autosomal Dominant Spastic Paraplegia Type 17

    Recessive Human phenotypes related to Spastic Paraplegia 24, Autosomal Recessive: 60 33 (show all 8) # Description HPO Frequency Orphanet Frequency HPO Source Accession 1 clonus[malacards.org] (74/209)/19% (28/151) Increased reflexes in the lower limbs 91% (195/214) Increased reflexes in the upper limbs 27% (54/204) Extensor plantar reflex 81% (174/216) Ankle clonus[academic.oup.com] […] tendon reflexes in the upper limbs 40/47 (85%) Increased tendon reflexes in the lower limbs 47/47 (100%) Presence of extensor plantar reflex 29/45 (64%) Presence of ankle clonus[bmcneurol.biomedcentral.com]

  • Upper Motor Neuron Disease

    ; UMNL neurological lesion involving any part of an upper motor neurone, e.g. stroke, cerebral palsy; characterized by clonus, exaggerated tendon reflexes, extensor plantar[medical-dictionary.thefreedictionary.com] […] group of muscles, including the abductor pollicis brevis (APB) and first dorsal interosseous (FDI), when compared to the abductor digit minimi (ADM) [Figure 1]. 14,22 This[acnr.co.uk] […] spasticity Initial resistance to motion is strongest Once initial resistance gives-way, resistance to motion is less for remaining range of motion Hyperreflexia with or without Clonus[fpnotebook.com]

  • Cervical Osteoarthritis

    Objective neurological deficit (upper motor neurone signs in the legs (eg, up-going plantars, hyperreflexia, clonus, spasticity); lower motor neurone signs in the arms (eg[patient.info] […] groups, especially in the extremities poor or pathologic tandem gait atrophy of the hand’s thenar prominence (the fleshy fat pad just superior to the thumb on the ventral[americannursetoday.com] On physical examination, you may find some or many of the following: clonus or spasticity of the lower extremities sensory changes (light touch, pinprick sensation, or temperature[americannursetoday.com]

  • Spastic Paraplegia Type 38, Autosomal Dominant

    Recessive Human phenotypes related to Spastic Paraplegia 24, Autosomal Recessive: 60 33 (show all 8) # Description HPO Frequency Orphanet Frequency HPO Source Accession 1 clonus[malacards.org] Ankle clonus, and extensor plantar responses are uniformly present. 41. Hoffman sign may be observed. 42.[slideshare.net] […] difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia 24, Autosomal Recessive: clonus, difficulty standing[malacards.org]

  • Progressive Muscular Atrophy

    […] loss causes initially increased electrical excitability leading to fasciculations, and later muscle weakness and atrophy; upper motor neuron involvement causes spasticity, clonus[neuropathology-web.org] […] group of muscles, including the abductor pollicis brevis (APB) and first dorsal interosseous (FDI), when compared to the abductor digit minimi (ADM) [Figure 1]. 14,22 This[acnr.co.uk] […] ultimately resulting in terminal respiratory failure, 19 although rarely may be the presenting symptom. 20,21 The “split hand” sign refers to preferential wasting of the thenar[acnr.co.uk]

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