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12 Possible Causes for Clonus of Ankle or Knee, Lower Limb Vibratory Sense Decreased, Spasticity - Hyperreflexia

  • Autosomal Dominant Spastic Paraplegia Type 10

    ) is a rare type of hereditary spastic paraplegia that can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia and extensor plantar[orpha.net] limbs Decreased lower limb vibratory sense Decreased vibratory sense in lower limbs Decreased vibratory sense in the lower extremities Decreased vibratory sense in the lower[rarediseases.info.nih.gov] Reflexes were very brisk with spread at the biceps and knees; there was sustained clonus at the ankles. Gait was very spastic, and he scissored while walking.[onlinelibrary.wiley.com]

  • Autosomal Dominant Spastic Paraplegia Type 17

    Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia[malacards.org] There was a flexion deformity of the right hip and knee and shortening of the achilles tendon. The left hip, knee, and ankle were fixed in extension.[jnnp.bmj.com] limbs Decreased lower limb vibratory sense Decreased vibratory sense in lower limbs Decreased vibratory sense in the lower extremities Decreased vibratory sense in the lower[rarediseases.info.nih.gov]

  • Autosomal Dominant Spastic Paraplegia Type 19

    […] paraplegia 8 is a neurologic disorder characterized by severe lower limb spasticity and weakness.[cags.org.ae] […] extention 3.5 3 2 2 4.5 Ankle flexion 4 3 1.5 2.5 5 Ankle extention 3.5 3.5 1.5 2 5 Toes 3 3 1 1.5 3 Muscle wasting - - Hyperactive reflexes: Knee Ankle Clonus - Babinski[bmcneurol.biomedcentral.com] Diagnosis of SPG is established by the following clinical features 1, 2 : Typical clinical symptoms of spastic gait impairment and neurologic findings of spastic weakness,[centogene.com]

  • Autosomal Dominant Spastic Paraplegia Type 12

    OMIM : 58 Spastic paraplegia-12 is an autosomal dominant neurodegenerative disorder characterized by lower limb spasticity and hyperreflexia, resulting in walking difficulties[malacards.org] Neurologic examination revealed hyperreflexia and spasticity in the lower extremities, weakness of hip flexion and ankle dorsiflexion, extensor plantar response, diminished[neurology.org] Diagnosis of SPG is established by the following clinical features 1, 2 : Typical clinical symptoms of spastic gait impairment and neurologic findings of spastic weakness,[centogene.com]

  • Autosomal Dominant Spastic Paraplegia Type 4

    Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia[ncbi.nlm.nih.gov] sense in lower limbs Decreased vibratory sense in the lower extremities Decreased vibratory sense in the lower limbs Diminished vibratory sensation in the legs [ more ] 0002166[rarediseases.info.nih.gov] There was a flexion deformity of the right hip and knee and shortening of the achilles tendon. The left hip, knee, and ankle were fixed in extension.[jnnp.bmj.com]

  • Autosomal Recessive Spastic Paraplegia Type 7

    , hyperreflexia, lower-limb weakness and decreased vibration sensation 37 yrs, 22 – 60 yrs AD Uncomplicated KIAA0196 (SPG8) DNA Sequencing 25 – 42 yrs AR Uncomplicated/ Paraplegin[1pdf.net] Clinical features of the disease include lower limb spasticity and weakness, spastic ataxic gait, hyperreflexia, extensor plantar responses, pyramidal signs, decreased vibratory[link.springer.com] Neither ankle nor knee clonus was observed. He had no involuntary movements, rigidity or bradykinesia. Truncal and limb ataxia appeared exacerbated.[nature.com]

  • Autosomal Dominant Spastic Paraplegia Type 36

    Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia[malacards.org] […] extention 3.5 3 2 2 4.5 Ankle flexion 4 3 1.5 2.5 5 Ankle extention 3.5 3.5 1.5 2 5 Toes 3 3 1 1.5 3 Muscle wasting - - Hyperactive reflexes: Knee Ankle Clonus - Babinski[bmcneurol.biomedcentral.com] The essential clinical findings are slowly progressive and often include severe spasticity, hyperreflexia, and weakness in a pyramidal distribution, noticeably in both lower[emedicine.medscape.com]

  • Spinal Cord Compression

    Physical Findings on physical examination correspond to the location of the tumor, degree of cord impingement, and duration, and may include the following: Spasticity; hyperreflexia[emedicine.medscape.com] Some of these signs include very brisk reflexes when tapping the correct spot below the knee cap, a bouncing reflex when the ankle is stretched called clonus, and unsteadiness[backpain-guide.com] Upper motor neurone signs in the lower limbs (Babinski's sign: up-going plantar reflex, hyperreflexia, clonus, spasticity).[patient.info]

  • Autosomal Dominant Spastic Paraplegia Type 38

    Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia[malacards.org] […] extention 3.5 3 2 2 4.5 Ankle flexion 4 3 1.5 2.5 5 Ankle extention 3.5 3.5 1.5 2 5 Toes 3 3 1 1.5 3 Muscle wasting - - Hyperactive reflexes: Knee Ankle Clonus - Babinski[bmcneurol.biomedcentral.com] Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterised by progressive spasticity and hyperreflexia[ncbi.nlm.nih.gov]

  • Autosomal Dominant Spastic Paraplegia Type 31

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[malacards.org] limb weakness and spasticity, sphincter dysfunction, decreased vibratory sense at the ankles and with additional manifestations including optical neuropathy, nystagmus, strabismus[mendelian.co] Upon examination, he was found to have spastic paraparesis, hyperreflexia, clonus of both ankle and knee jerks, and upgoing plantar reflexes, with normal nerve conduction[cags.org.ae]

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