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445 Possible Causes for Clubbed Finger, Splenomegaly

  • Mucopolysaccharidosis 2

    Individuals with this disorder may experience the following signs: abnormal retina, heart murmur and leaky heart valves, enlarged liver (hepatomegaly) enlarged spleen (splenomegaly[secure.ssa.gov] On examination, he was short statured, with a big head, protruding abdomen, coarse skin, swollen wrist joints, and clubbed fingers. There was mild mental retardation.[amhsr.org] […] degenerative joints causing joint stiffness Spinal cord defects Sleep disorder such as sleep apnea Decrease in mental cognition Enlarged liver (hepatomegaly) and enlarged spleen (splenomegaly[dovemed.com]

  • Portal Cirrhosis

    Liver cirrhosis: Liver cirrhosis with an inhomogeneous liver with irregular contour and ascites and splenomegaly Liver cirrhosis: Liver cirrhosis with an irregular liver contour[ultrasoundcases.info] The complete syndrome includes clubbing of the fingers and toes, cylindrical enlargement of legs and arms due to involvement of periosteal bone as well as of the skin, synovitis[annals.org] Finger clubbing. Dupuytren's contracture. Other signs include: Hepatomegaly and a nodular liver. Oedema. Gynaecomastia and male hair loss pattern.[patient.info]

  • Congenital Hepatic Fibrosis

    We describe the first case of CHF presenting in an otherwise healthy child, with thrombocytopenia and splenomegaly as the only manifestations of the disease.[ncbi.nlm.nih.gov] […] of the fingers 7 years postoperatively.[ncbi.nlm.nih.gov] This retrospective study shows that certain findings (ie, liver morphologic and associated ductal plate abnormalities, varices, splenomegaly, and renal abnormalities) are[ncbi.nlm.nih.gov]

  • CINCA Syndrome

    Failure to thrive, mild splenomegaly, and refractory iron-deficiency anemia, without a detectable source of infection, led to no definitive diagnosis, and an extensive investigation[jrheum.org] At the patient’s initial visit, a clinical examination confirmed the presence of a rash on her body with a saddle nose and clubbed fingers.[joii-journal.springeropen.com] The patient was apnoeic, pale and showed significant hepato-splenomegaly.[ped-rheum.biomedcentral.com]

  • Alcoholic Liver Disease

    Splenomegaly : Portal hypertension causes the spleen to enlarge (a condition called splenomegaly).[msdmanuals.com] fingers) blotchy red palms significant weight loss weakness and muscle wasting confusion and memory problems, trouble sleeping (insomnia) and changes in your personality[nhs.uk] […] steatosis (fatty liver) From the collection of Dr McClain; used with permission History & Exam Key Factors abdominal pain hepatomegaly hematemesis and melena venous collaterals splenomegaly[online.epocrates.com]

  • Subacute Bacterial Endocarditis

    Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission.[ncbi.nlm.nih.gov] SBE manifests many skin findings including petechiae, splinter hemorrhages of the nails, Osler's and laneway lesions, clubbing of the fingers, and findings suggestive of angiitis[ncbi.nlm.nih.gov] Findings compatible with both SBE and marantic endocarditis due to a B-cell lymphoproliferative disorder included an elevated ESR, and splenomegaly.[ncbi.nlm.nih.gov]

  • Primary Biliary Cirrhosis

    […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org] The multivariate analysis identified two independent predictive factors: low albumin level and splenomegaly ( Table 3 ).[nejm.org] Clinically overt liver disease was defined by the presence of at least one of the following signs or symptoms: jaundice, fatigue, pruritus, hepatomegaly, and splenomegaly.[nejm.org]

  • Mucopolysaccharidosis

    […] trunk ( dwarfism ), dysplasia (abnormal bone size and/or shape) and other skeletal irregularities, thickened skin, enlarged organs such as liver ( hepatomegaly ) or spleen ( splenomegaly[en.wikipedia.org] Heart Inspection Neck vein- distended/ not distended Clubbing of fingers-yes/no Cyanosis, central, peripheral Edema Palpation Apical pulse Capillary Refill Auscultation Heart[slideshare.net] […] slowly to 20-30mg/kg/day in divided doses 40. 40 Adverse effect drowsiness, diplopia, vertigo, araxia, blurred vision, GI upset, skin reaction, lymphadenopathy, eosinophilia, splenomegaly[slideshare.net]

  • Hepatopulmonary Syndrome

    Case Report A 17-year-old male presented with progressive splenomegaly since age 7 years, recurrent epistaxis and skin bleeds for the last 5 years, and worsening dyspnoea[acgcasereports.gi.org] She had been suffered from progressive liver failure with dyspnea, clubbing fingers, and cyanosis.[ncbi.nlm.nih.gov] For addressing the issue of splenomegaly, imaging work up was carried out.[casereports.in]

  • Ulcerative Colitis

    Computed tomography (CT) revealed systemic lymphadenopathy, splenomegaly, and thickening of the sigmoid colon and rectum walls. 18F-fluorodeoxy-glucose positron emission tomography[ncbi.nlm.nih.gov]

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