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274 Possible Causes for Clubbed Finger, Splenomegaly

  • Portal Cirrhosis

    Liver cirrhosis: Liver cirrhosis with an inhomogeneous liver with irregular contour and ascites and splenomegaly Liver cirrhosis: Liver cirrhosis with an irregular liver contour[ultrasoundcases.info] The complete syndrome includes clubbing of the fingers and toes, cylindrical enlargement of legs and arms due to involvement of periosteal bone as well as of the skin, synovitis[annals.org] Finger clubbing. Dupuytren's contracture. Other signs include: Hepatomegaly and a nodular liver. Oedema. Gynaecomastia and male hair loss pattern.[patient.info]

  • Subacute Bacterial Endocarditis

    Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission.[ncbi.nlm.nih.gov] Abstract SBE manifests many skin findings including petechiae, splinter hemorrhages of the nails, Osler's and laneway lesions, clubbing of the fingers, and findings suggestive[ncbi.nlm.nih.gov] Findings compatible with both SBE and marantic endocarditis due to a B-cell lymphoproliferative disorder included an elevated ESR, and splenomegaly.[ncbi.nlm.nih.gov]

  • CINCA Syndrome

    Failure to thrive, mild splenomegaly, and refractory iron-deficiency anemia, without a detectable source of infection, led to no definitive diagnosis, and an extensive investigation[jrheum.org] clubbing.[en.wikipedia.org] Nausea, vomiting and abdominal pain with flares, or with elevated intracranial pressure (ICP). [6] Lymphatic: Splenomegaly.[autoinflammatory-search.org]

  • Mucopolysaccharidosis 2

    Individuals with this disorder may experience the following signs: abnormal retina, heart murmur and leaky heart valves, enlarged liver (hepatomegaly) enlarged spleen (splenomegaly[secure.ssa.gov] On examination, he was short statured, with a big head, protruding abdomen, coarse skin, swollen wrist joints, and clubbed fingers. There was mild mental retardation.[amhsr.org] […] degenerative joints causing joint stiffness Spinal cord defects Sleep disorder such as sleep apnea Decrease in mental cognition Enlarged liver (hepatomegaly) and enlarged spleen (splenomegaly[dovemed.com]

  • Mucopolysaccharidosis

    […] trunk (dwarfism), dysplasia (abnormal bone size and/or shape) and other skeletal irregularities, thickened skin, enlarged organs such as liver (hepatomegaly) or spleen (splenomegaly[en.wikipedia.org]

  • Primary Biliary Cirrhosis

    […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org] This may backup blood flow from other organs, causing splenomegaly , an enlarged spleen , and varices, swollen veins, especially in the esophagus and stomach that can predispose[medicinenet.com]

  • Chronic Obstructive Pulmonary Disease

    […] vaccination against hepatitis A and B and avoidance of alcohol and other hepatotoxic agents. 9 Progression of liver disease to cirrhosis may be heralded by the development of splenomegaly[dx.doi.org] Examples include: finger clubbing, wheezing, exercise intolerance, chest tightness, cough productive of sputum, and coughing up blood.[medicinenet.com] Clubbing of the fingers is rare and raises the suspicion of lung cancer or other lung disorders.[merckmanuals.com]

  • Liver Cirrhosis

    We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] […] become wider/thicker (clubbed fingers) hair loss swelling of the legs, ankles, feet (oedema) swelling of the abdomen (ascites) dark urine pale-coloured stools or very dark[britishlivertrust.org.uk] Cirrhosis signs, include jaundice, gynecomastia (up to one third of men), loss of axillary and pubic hair, ascites, and splenomegaly (due to portal hypertension), finger clubbing[symptoma.com]

  • Hepatopulmonary Syndrome

    Case Report A 17-year-old male presented with progressive splenomegaly since age 7 years, recurrent epistaxis and skin bleeds for the last 5 years, and worsening dyspnoea[acgcasereports.gi.org] She had been suffered from progressive liver failure with dyspnea, clubbing fingers, and cyanosis.[ncbi.nlm.nih.gov] Clinically the patient may have signs and symptoms of liver disease, including gastrointestinal bleeding, esophageal varices, ascites, palmar erythema, and splenomegaly.[medical-dictionary.thefreedictionary.com]

  • Macronodular Cirrhosis

    Splenomegaly. Portosystemic shunt (including oesophageal varices). Caput medusa.[brainscape.com] Splenomegaly Increased pressure in the portal vein is conducted to the splenic vein resulting in congestive enlargement of the spleen.[pathwaymedicine.org] Complications: Decompensation: development of jaundice, ascites, variceal hemorrhage or hepatic encephalopathy Portal hypertension: ascites ( spontaneous bacterial peritonitis), splenomegaly[pathologyoutlines.com]

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